H20-MSCA-Marie Sklodowska-Curie actions
Succinate-induced leukemic stem cell formation via epigenetic remodeling of hematopoietic stem cell
In life, no matter how small, changes can have huge impact on its quality. For hematopoietic stem cells (HSC), similar can happen. Through minor shifts, from normal to pre-leukemic and finally leukemic phenotype, generation of leukemic stem cells (LSC) results in overt malignancy, such is acute m...