0 projects

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KOSK-II-Katalyse og org.synt.kjemi II

Synthesis Directed towards Development of Potential Antituberculosis Drugs with Novel Mechanism of Action

Tuberculosis (TB) is the major cause of death from a single infectious agent among adults in developing countries. Human immunodeficiency virus (HIV) infections have further increased TB morbidity and mortality. It has been estimated that ca. 30 million p eople will die from tuberculosiswithin th...

Awarded: NOK 3.7 mill.

Project Period: 2007-2011

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Catalytic dehydrogenation of NGL components. Application of in situ spectroscopic techniques for studying dehydrogenation catalysts.

Catalytic dehydrogenation of NGL is a vital process for the production of olefins. Typically, Cr-oxide or Pt-based catalysts are used for commercial processes. The project focuses on the application of operando and in situ spectroscopic studies of Cr-oxid e based catalysts during dehydrogenation ...

Awarded: NOK 0.83 mill.

Project Period: 2007-2009

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Carbocation mediated hydrocarbon reactions over acidic zeotype catalysts

Acid catalysis over zeotype materials is one of the most important and fundamental topics in catalysis. Basic natural gas conversion processes like MTO (methanol to olefins), dimerisation, and C4 isomerisation can be performed using acid catalysis by zeol ites and/or microporous SAPOs. In additio...

Awarded: NOK 3.1 mill.

Project Period: 2007-2010

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Organisk Kjemisk Vintermøte 2007

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Awarded: NOK 40,885

Project Period: 2007-2007

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Theory-assisted design of functional group-tolerant catalysts for olefin conversion

The goal of the project is to design new transition-metal complexes with a reactivity that is highly selective for the alkene double bond function. The selectivity will be exploited in the development of functional group tolerant catalysts for an importan t class of olefin refinement process: Ole...

Awarded: NOK 3.9 mill.

Project Period: 2007-2011

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

Catalysis with Pd Complexes that have Chelating N-Heterocyclic Carbene Ligands

The Tilset research group has recently developed the first members of a new class of chelating ligands, iminocarbenes, that form well-defined homogeneous Pd complexes with hemilabile, 5- and 6-membered, chelate structures. The use of these Pd complexes in the catalytic transformation of organic ...

Awarded: NOK 2.2 mill.

Project Period: 2007-2010

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Design and synthesis of novel aspartic protease inhibitors.

This project will focus on the development of much needed novel inhibitors of the aspartic proteases related to HIV/AIDS and Alzheimers disease. In order to pursue these goals, the project seeks to establish a strong research group in medicinal chemistry at the Centre for Pharmacy at the Universi...

Awarded: NOK 2.3 mill.

Project Period: 2008-2012

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

Det 23. Organisk-Kjemisk Vintermøte 2008

The Organic Winter Meeting is the national meeting in organic chemistry in Norway. It is a conference under the umbrella of the Norwegian Chemical Society, which has given me the task to organize the meeting. Since its infancy the tradition has been to invite 3-4 eminent chemists, covering vari...

Awarded: NOK 49,999

Project Period: 2008-2008

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

Quantum chemical modelling of metal-support interactions in metal-based catalysts

Production of synthesis gas (carbon monoxide and hydrogen) is a process of major importance for chemical upgrading of natural gas. In this process, a catalyst consisting of metal clusters supported on an oxide surface is used. The project's main challenge will be to elucidate the role of strong ...

Awarded: NOK 1.7 mill.

Project Period: 2008-2011

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Norsk Katalysesymposium 23.-24. oktober 2007

Katalysesymposiet er Faggruppa for katalyse (Norsk kjemisk selskap) sitt viktigste arrangement. Faggruppas medlemmer er spredt over hele Norge, og samles bare til årsmøtet og katalysesymposiet som dermed får en viktig nasjonal faglig funksjon. Symposiet f ungerer tradisjonelt også som årsmøte for...

Awarded: NOK 29,999

Project Period: 2007-2007

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Fundamental understanding of catalyst nanoparticles by atomic scale chemical imaging

Fundamental study down to the atomic level is crucial for improving our understanding of catalysts and enhancing our ability for their rational design. The present project deals with exploring advanced TEM techniques such as aberration corrected microscop y and environmental TEM for imaging of co...

Awarded: NOK 2.8 mill.

Project Period: 2011-2013

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Structure-Activity Relationship and Binding Mode for Cyclopentapeptide Antagonists of CXCR4, a Therapeutic Target in HIV/AIDS and Oncology

The main physiological role of the human G-protein coupled chemokine receptor CXCR4 and its natural ligand SDF-1a is homing of leukocytes and embryonic development. However, CXCR4 has also been shown to be involved in the pathology of several serious dise ases, most notably AIDS (HIV entry point ...

Awarded: NOK 2.9 mill.

Project Period: 2009-2013

Location: Troms - Romsa - Tromssa

KOSK-II-Katalyse og org.synt.kjemi II

Synthesis, molecular modelling and biological evaluation of protectin D1 and analogs

Inntak av omega-3-fettsyrer som eicosapentaensyre (EPA) og docosaheksaensyre (DHA) har i flere studier vist å gi positive helseeffekter. Disse omega-3-fettsyrene finnes i tran og fet fisk. De eksakte molekylære årsakene til disse positive helseeffektene e r ennå ikke klarlagt. Ny forskning utfø...

Awarded: NOK 2.8 mill.

Project Period: 2010-2014

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Rare-Earth Metal-Promoted C-H Bond Activation

The production of valuable chemicals via selective functionalization of saturated and unsaturated hydrocarbons is a major challenge in the field of contemporary organometallic chemistry. A particularly attractive substrate is methane which has previously been successfully C-H bond activated by ...

Awarded: NOK 1.7 mill.

Project Period: 2008-2010

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

C-H Activation reactions at neutral cyclometalated Pt complexes

The Tilset group has made important contributions towards selective C-H activation and functionalization at platinum complexes in solution and, recently, in development of novel Pt-containing metal-organic frameworks that may be of interest for catalytic applications. One drawback (this applies t...

Awarded: NOK 1.7 mill.

Project Period: 2008-2010

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Design and optimisation in organic synthesis:Optimisation of telscope reactions and methodologies base on orthogonal experiments

Telescope reactions: Assume that a three-step reaction is to be optimised: Lay out a statistical design to map the first step. Run the experiments an determine the responses. The response matrix Y=[y1 y2 ....ur] summarises the results. A principal compone nt model will determine the number of ind...

Awarded: NOK 2.8 mill.

Project Period: 2009-2013

Location: Troms - Romsa - Tromssa

KOSK-II-Katalyse og org.synt.kjemi II

Engineering of Pt nanoparticles in Propane Dehydrogenation

Nanocrystals with well controlled size, shape and surface composition provides excellent opportunities not only in fundamental study of heterogeneous catalysis but also for improving existing catalysts or design new catalysts for chemical processes. Porpa ne dehydrogenation is a conventional chem...

Awarded: NOK 2.4 mill.

Project Period: 2009-2012

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

IUPAC 18th International Conference on Organic Synthesis

As outlined in the application for IUPAC Sponsorship (see attached Project description) the conference programme will give a broad and thorough overview of the current trends in organic synthesis. To secure the quality of the programme an outstanding Inte rnational Advisory Board has been appoint...

Awarded: NOK 0.35 mill.

Project Period: 2010-2010

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

MICROPEP II - Design and synthesis of antimicrobial peptides targeted against pathogenic fungi.

Radiation treatment of head and neck cancer must be suspended due to Candida infection in the mouth and throat. This is just an example showing the need for new treatment of fungal infections. The present project addresses these issues by proposing to ide ntify pharmacophores for antimicrobial ac...

Awarded: NOK 4.0 mill.

Project Period: 2007-2011

Location: Troms - Romsa - Tromssa

KOSK-II-Katalyse og org.synt.kjemi II

Design and optimisation in organic synthesis: Methodologies for the optimisation of multi-step one-pot batch processes

Assume tha a three step one-pot reaction is tt be optimised: Lay out a design to map the first step. Depending on how detailed information is desired, this can be a fractional factorial, factoral, D-optimal, or a response surface design for quardratic m odels. Run the experiments and detrmine t...

Awarded: NOK 1.8 mill.

Project Period: 2007-2009

Location: Troms - Romsa - Tromssa

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