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CL1-Health

Better rEal-world healTh-daTa distributEd analytics Research platform

In recent years, data-driven medicine has gained increasing importance in terms of diagnosis, treatment, and research due to the exponential growth of healthcare data. The linkage of cross-border health data from various sources, including genomics, and analysis via innovative approaches based on...

Awarded: NOK 4.9 mill.

Project Period: 2023-2027

Location: Troms - Romsa - Tromssa

CL1-Health

Targeting Epstein-Barr Virus Infection for Treatment and Prevention of Multiple Sclerosis

Targeting Epstein-Barr Virus Infection for Treatment and Prevention of Multiple Sclerosis

Awarded: NOK 29.6 mill.

Project Period: 2023-2028

Location: Rogaland og 5 andre

CL1-Health

Healthy Working environments for all Ages: An evidence-driven framework

The WAge project will develop and validate the first comprehensive framework for assessing and understanding the roles and interactions between physical and psychosocial risk factors across age groups through robust modelling and policy-relevant evidence gathering. Through the proposed framework,...

Awarded: NOK 20.1 mill.

Project Period: 2023-2027

Location: Trøndelag - Trööndelage

CL1-Health

COordination MEchanism for Cohorts and Trials

The overall goal of COMECT is to coordinate activities across Europe’s strategic adaptive platform trials (APTs) and cohort studies (CS) on infectious diseases (IDs) with epidemic or pandemic potential, by overseeing and facilitating dialogue, sharing of good practices, promoting collaboration an...

Awarded: NOK 11.6 mill.

Project Period: 2023-2026

Location: Oslo

CL1-Health

Development of a global diagnostic ecosystem for detecting and monitoring emergency-prone pathogens across species and in a unified way

Development of a global diagnostic ecosystem for detecting and monitoring emergency-prone pathogens across species and in a unified way

Awarded: NOK 9.4 mill.

Project Period: 2023-2027

Location: Vestland

CL1-Health

CorrelAtes of Protective immuniTy-driven Investigation of malaria VAccine combinaTion stratEgies

Malaria remains a serious health concern worldwide, with P. falciparum considered one of the deadliest human parasites. Yet, the currently approved vaccine against malaria (RTS,S/AS01) offers limited protection due to challenges in vaccine development. Using current advances made in understanding...

Awarded: NOK 0.81 mill.

Project Period: 2023-2028

Location: Oslo

CL1-Health

Obesity: Biological, socioCultural, and environmental risk Trajectories

Obesity in Europe disproportionately affects people and communities with a lower socioeconomic position (SEP). Effective preventive approaches require consideration of the complex and dynamic interplay between (SEP-specific) biological, sociocultural and environmental risk factors of obesity acro...

Awarded: NOK 16.3 mill.

Project Period: 2023-2028

Location: Oslo

CL1-Health

Applying ARtificial Intelligence to Define clinical trajectorieS for personalized predicTiOn and early deTEctiOn of comorbidiTy and muLtimorbidiTy pattErnS

Applying ARtificial Intelligence to Define clinical trajectorieS for personalized predicTiOn and early deTEctiOn of comorbidiTy and muLtimorbidiTy pattErnS

Awarded: NOK 2.2 mill.

Project Period: 2023-2028

Location: Oslo

CL1-Health

PREDICTION OF ALZHEIMER’S DISEASE USING AN AI DRIVEN SCREENING PLATFORM

PREDICTION OF ALZHEIMER’S DISEASE USING AN AI DRIVEN SCREENING PLATFORM

Awarded: NOK 11.9 mill.

Project Period: 2023-2027

Location: Rogaland

CL1-Health

European Partnership for Personalised Medicine

EP PerMed is a new European Partnership dedicated to Personalised Medicine (PM). It supports PM-related R&I, but also facilitates and accelerates all steps so that PM achievements successfully pass through the full value continuum to be implemented in sustainable health systems for the benefit of...

Awarded: NOK 37.2 mill.

Project Period: 2023-2033

Location: Akershus

CL1-Health

HARMONISED APPROACH TO EARLY FEASIBILITY STUDIES FOR MEDICAL DEVICES IN THE EUROPEAN UNION

HARMONISED APPROACH TO EARLY FEASIBILITY STUDIES FOR MEDICAL DEVICES IN THE EUROPEAN UNION

Awarded: NOK 11.0 mill.

Project Period: 2023-2027

Location: Oslo

CL1-Health

Augmented Social Play (ASP): smartphone-enabled group psychotherapeutic interventions that boost adolescent mental health by supporting real-world connection and sense of belonging

Augmented Social Play (ASP): smartphone-enabled group psychotherapeutic interventions that boost adolescent mental health by supporting real-world connection and sense of belonging

Awarded: NOK 0.58 mill.

Project Period: 2023-2027

Location: Trøndelag - Trööndelage

CL1-Health

A TRUSTworthy speech-based AI monitorING system for the prediction of relapse in individuals with schizophrenia

A TRUSTworthy speech-based AI monitorING system for the prediction of relapse in individuals with schizophrenia

Awarded: NOK 21.3 mill.

Project Period: 2023-2028

Location: Troms - Romsa - Tromssa

CL1-Health

PRecisIon Cancer MEdicine RepurpOsing SystEm Using Pragmatic Clinical Trials

Millions of people in the EU are negatively affected by cancer, and cancer is one of the leading causes of death and morbidity in Europe (ecis.jrc.europa.eu). The PRIME-ROSE consortium will contribute to the Mission Cancer goal to optimise treatment and support quality of life of more than 3 mill...

Awarded: NOK 18.2 mill.

Project Period: 2023-2028

Location: Oslo

CL1-Health

Strengthening Clinical Trial Regulatory and Ethical review Oversight in East Africa

There is an increase in the number of drug development clinical trials conducted in Sub-Saharan Africa (SSA), including vaccine development studies for poverty-related diseases (PRDs) underway in SSA. These increases have not been matched with increase in regulatory support and ethical review for...

Awarded: NOK 2.1 mill.

Project Period: 2023-2026

Location: Oslo

CL1-Health

Strengthening Environmental Surveillance to Advance Public Health Action

The ODIN project aims at strengthening capacity for genomics and bioinformatics database management skills for generating, maintaining, and querying large genomic epidemiology data sets in sub-Saharan countries. To reach this goal, ODIN will develop a genomic surveillance system relying on enviro...

Awarded: NOK 9.1 mill.

Project Period: 2023-2026

Location: Vestland

CL1-Health

Implementation of an upgraded strategy to reach zero HIV transmission by breastfeeding in rural and urban settings in Zambia – the PROMISE-ZERO study

Implementation of an upgraded strategy to reach zero HIV transmission by breastfeeding in rural and urban settings in Zambia – the PROMISE-ZERO study

Awarded: NOK 2.8 mill.

Project Period: 2023-2027

Location: Vestland

CL1-Health

Reconstruction and Computational Modelling for Inherited Metabolic Diseases

Our overall objectives are to accelerate the diagnosis, and enable personalised management, of inherited metabolic diseases (IMDs). Established academic technology for statistical genomic analysis, deep learning-based prediction of protein structure, and whole-body metabolic network modelling sha...

Awarded: NOK 0.10 mill.

Project Period: 2023-2027

Location: Oslo

CL1-Health

Late-stage clinical development of Chikungunya vaccines in endemic countries (CHIKV) and Controlled Human Infection Models for SARS-CoV2 and other beta coronaviruses (CHIM).

A Framework Partnership Agreement (FPA) between the Coalition for Epidemic Preparedness Innovations (CEPI) and the European Union (EU) was signed in April 2019, to finance and coordinate the development of new medical countermeasures to prevent and contain infectious disease epidemics, which are ...

Awarded: NOK 707.3 mill.

Project Period: 2023-2028

Location: Oslo

CL1-Health

Practical strengthening of regulatory and ethics oversight on clinical trials in West Africa using Lassa Fever vaccine development projects and increase regulatory maturity level in targeted countries

The proposed strengthening project for clinical research oversight in ECOWAS region, consists of practical training of regulatory and ethics experts by exposing them to Lassa Fever vaccine development from early to late clinical stage. The exposure to novel technologies in vaccine development and...

Awarded: Hidden

Project Period: 2023-2025

Location: Oslo

CL1-Health

TOWARDS LARGE-SCALE ADAPTION AND TAILORED IMPLEMENTATION OF EVIDENCE-BASED PRIMARY CANCER PREVENTION PROGRAMMES IN EUROPE AND BEYOND

TOWARDS LARGE-SCALE ADAPTION AND TAILORED IMPLEMENTATION OF EVIDENCE-BASED PRIMARY CANCER PREVENTION PROGRAMMES IN EUROPE AND BEYOND

Awarded: NOK 1.8 mill.

Project Period: 2023-2027

Location: Vestland

CL1-Health

Novel advanced and repurposed therapeutics for vision restoration in a group of severe rare ocular surface diseases: from validation to first clinical investigations

Rare Eye Diseases (REDs) are a major cause of visual impairment and blindness in Europe, affecting patients of all ages. The RESTORE VISION Consortium identified a group of 7 REDs all affecting the cornea and ocular surface that cause severe vision impairment and blindness and have inadequate tre...

Awarded: NOK 1.1 mill.

Project Period: 2023-2027

Location: Vestfold

CL1-Health

DEVELOPING TRUSTWORTHY ARTIFICIAL INTELLIGENCE (AI)-DRIVEN TOOLS TO PREDICT VASCULAR DISEASE RISK AND PROGRESSION

The aim of VASCUL-AID is to predict the risk of cardiovascular events and progression of the vascular diseases Abdominal Aortic Aneurysm (AAA) and Peripheral Arterial Disease (PAD) to influence the course of disease improving the patient’s quality of life and care and assisting clinicians to make...

Awarded: NOK 4.4 mill.

Project Period: 2023-2029

Location: Vestland

CL1-Health

COMPREHENSIVE CANCER INFRASTRUCTURES 4 EUROPE

COMPREHENSIVE CANCER INFRASTRUCTURES 4 EUROPE

Awarded: NOK 3.2 mill.

Project Period: 2023-2026

Location: Oslo

CL1-Health

IMPlementing geriatric assessment for dose Optimization of CDK 4/6-inhibitors in older bReasT cAncer patieNTs

Current evidence from both randomized trials and real-world evidence studies suggests that older breast cancer patients derive clinical benefit from the addition of CDK 4/6-inhibitors to endocrine therapy but with higher risk for adverse events and treatment discontinuation compared to younger pa...

Awarded: NOK 3.7 mill.

Project Period: 2023-2028

Location: Akershus

CL1-Health

International Study for Treatment of Childhood Relapsed ALL 2020

Relapse of acute lymphoblastic leukemia (ALL) remains a leading cause of mortality in childhood cancer. IntReALL 2020 will conduct randomized and historically controlled trials in children with relapsed B-cell precursor (BCP) ALL with the aim to replace toxic chemotherapy with better tolerated an...

Awarded: NOK 1.1 mill.

Project Period: 2023-2028

Location: Oslo

CL1-Health

Establishing of Cancer Mission Hubs: Networks and Synergies

Cancer- healthcare, research and innovation face core common challenges, such as fragmentation of initiatives and distancing from important stakeholders, requiring coordinated solutions. These challenges are recognized in Horizon Europe’s Cancer Mission Implementation Plan and in Europe’s Beating...

Awarded: NOK 3.7 mill.

Project Period: 2023-2026

Location: Oslo og 3 andre

CL1-Health

Mitigating Antimalarial Resistance Consortium in South-East Africa

Mitigating Antimalarial Resistance Consortium in South-East Africa

Awarded: NOK 3.0 mill.

Project Period: 2023-2027

Location: Oslo

CL1-Health

Prioritization, incentives and Resource use for sUstainable DENTistry

Oral diseases and conditions are the 3rd most expensive diseases to treat in the EU. They affect about half of the EU population. As highlighted in the 2021 WHO Oral Health Resolution, there are major challenges in the financing of oral health care: in deviation from the UN and WHO goal of Univer...

Awarded: NOK 1.0 mill.

Project Period: 2023-2027

Location: Oslo

CL1-Health

VALUATION OF ENVIRONMENTAL STRESSORS

VALUATION OF ENVIRONMENTAL STRESSORS

Awarded: NOK 3.6 mill.

Project Period: 2023-2025

Location: Oslo

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