0 projects

Date from new to old

BIOTEK2021-Bioteknologi for verdiskaping

Development of technology for flow cytometry- and other cell-based, high-content, high-throughput analyses to support marine bioprospecting

ChemBioNet Norway - Norwegian Chemical Biology Platforms is a national network of HTS screening platforms (part of ESFRI-project EU-Openscreen) that support marine bioprospecting and drug screening. A joint application to the Infrastructure Programme for investments to support marine bioprospect...

Awarded: NOK 4.0 mill.

Project Period: 2011-2015

Location: Oslo

BIOTEK2021-Bioteknologi for verdiskaping

Nuclear receptor ligands from Arctic marine organisms; Bioprospecting, structure, synthesis and evaluation as drug to treat metabolic syndro

Obesity is a major cause of diseases that can increase morbidity and mortality. Obesity leads to metabolic disorders (MD) including hyperglycemia and dyslipidemia. Current treatment includes ligands for the metabolite-activated transcription factors (PPAR s, LXRs). Despite their beneficial effect...

Awarded: NOK 4.7 mill.

Project Period: 2011-2016

Location: Troms - Romsa - Tromssa

BIOTEK2021-Bioteknologi for verdiskaping

Establishment of a bioprospecting network: Searching for novel anti-cancer agents in plants and microorganisms.

The project will gather experts in the field of natural products chemistry, microbiology and bioactive compounds, cell and tumour biology to make a bioprospecting cluster. This cluster will work to shorten the translational pipeline from discovery of a bi oactivity to clinical trials. The main pa...

Awarded: NOK 0.23 mill.

Project Period: 2011-2013

Location: Vestland

FUGE-Funksjonell genomforskn.i Norg

BIOPROSP 2011

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Awarded: NOK 0.15 mill.

Project Period: 2011-2011

Location: Troms - Romsa - Tromssa

BIOTEK2021-Bioteknologi for verdiskaping

Targeted screening technology for identification of bioactive agents with a potential for use in anti-cancer treatment from marine bacteria

I dette prosjektet har vi undersøkt ca 1000 ekstrakter fra en Actinomycete samling (bakterier) isolert fra Trondheimsfjorden med hensyn på anti-kreft aktivitet. Actinomyceter er bakteriene som er kjent å produsere mange ulike agens med anti-bakterie og anti-sopp egenskaper. Vi har undersøkt om de...

Awarded: NOK 3.0 mill.

Project Period: 2011-2014

Location: Trøndelag - Trööndelage

BIOTEK2021-Bioteknologi for verdiskaping

Kinase Modulators from Marine Bioprospecting

Approximately 40% of the population living in Norway today will receive a cancer diagnosis in their lifetime and many will die from their disease. Despite several decades of intensive research efforts, the therapeutic options for treating cancer are still limited to traditional interventions bas...

Awarded: NOK 8.4 mill.

Project Period: 2011-2015

Location: Oslo

BIOTEK2021-Bioteknologi for verdiskaping

Purified heparin from marine raw materials

Hepmarin AS has developed and patented processes to produce Heparin, using marine species as raw material. These are more efficient and cheaper than existing technology, solves contamination issues through the use of a traceable raw material source, and w ill not have the ethical/religious issues...

Awarded: NOK 1.2 mill.

Project Period: 2011-2012

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Malaria control in Africa using plant extracts - Project establishment support

In the current pilot project phase we want to establish an international interdisciplinary research group to develop a proposal for a 3-year main project with the aim of developing locally based phytomedicines and insecticides to control malaria in Africa . The research group consists of scientis...

Awarded: NOK 0.50 mill.

Project Period: 2011-2011

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

System biology of microorganisms: Enterococcus faecalis and Lactobacillus plantarum

SysMO-LAB2 aims to extend and further develop comparative systems biology approaches to understand similarities and differences in fermentation behaviour of four Lactic Acid Bacteria (LAB). Lactococcus lactis, used in dairy food applications; Enterococcus faecalis, a major (fecal) contaminant in...

Awarded: NOK 5.5 mill.

Project Period: 2010-2014

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Application for support of the annual contact meeting of the Norwegian Biochemical Society.

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Awarded: NOK 0.36 mill.

Project Period: 2010-2012

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Software for genome-based bioprospecting

Genomes of several rare actinomycete bacteria isolated from the Trondheim fjord in the course of the bioprospecting project have been sequenced. NTNU is now developing methods for activation and/or heterologous expression of these silent gene clusters for biosynthesis of potential drug leads. Ho...

Awarded: NOK 0.44 mill.

Project Period: 2010-2011

Location: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

Norproteomics/Biohealth

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Awarded: NOK 2.3 mill.

Project Period: 2009-2011

Location: Vestland

FUGE-Funksjonell genomforskn.i Norg

From trust to hope.The interface between science and society in late modernity.

In sociology the concept of trust has for a long time dominated analyses of the general relation between science and society (Giddens 1990; Beck 1986; Luhmann 1973). The main thesis of our project is that we are tendentially witnessing an epochal shift in this relation which may be characterized...

Awarded: NOK 1.00 mill.

Project Period: 2009-2010

Location: Vestland

FUGE-Funksjonell genomforskn.i Norg

Stimulating sustainable innovation in aquaculture

This project aims to explore the need for legislation to promote sustainable innovation in aquaculture. Breeding companies, marine bioprospecting institutions and investors in genetic engineering need protection of their improved genetic material to assur e revenues from innovation and investment...

Awarded: NOK 5.0 mill.

Project Period: 2009-2012

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Pathogenesis of complex genetic diseases, using pre-eclampsia as a model

Pre-eclampsia (PE) is the most common pregnancy-associated complication in the Western world. The syndrome is a major contributor to maternal and fetal illness/death. No therapeutic treatment exists. The mechanisms involved in development of PE remain to be elucidated. Observations suggest immu...

Awarded: NOK 8.5 mill.

Project Period: 2008-2013

Location: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

Establishment/Evaulation of a Biomolecular NMR Structure Platform and Instrumentation Requirements for Biomolecular NMR

All molecules function through their three-dimensional structures as well as through their chemical properties. Understanding the mode of action of proteins and other biomolecules as well as optimal medical and biotechnological exploitation of these molec ules therefore relies to a large extent o...

Awarded: NOK 0.50 mill.

Project Period: 2008-2009

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

The CIGENE node of the Norwegian Sequencing and Genotyping Service Platform

CIGENE's mandate in the FUGE I period has been to: A. Establish and maintain a national core facility providing: (i) - a high-throughput SNP-typing service for human, animal, plant and microbial materials, (ii) - key competence concerning identification a nd methodological integration of experime...

Awarded: NOK 10.0 mill.

Project Period: 2008-2012

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Channel 2 application for continuation of FUGE MIC Trondheim in FUGE II period (2007-2011)

MIC Trondheim wants to continue in the FUGE II period with MR as the core technology, and will expand in capacity with acquisition of new MR equipment, and expand the high-level competence necessary for offering a wide variety of methods tailored to the u ser's research tasks. A goal is to establ...

Awarded: NOK 5.6 mill.

Project Period: 2008-2013

Location: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

Towards personalized therapy for breast cancer

Purpose of the project: Few protocols have so far been designed with attempts to characterize the systems biology of cancer. The objective of the project is to translate information obtained from integrative molecular analysis of material collected from i ndividual cancer patients, through valida...

Awarded: NOK 10.0 mill.

Project Period: 2008-2012

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Host-virus interactions in Atlantic salmon

Infectious pancreatic necrosis virus (IPNV) and infectious salmon anemia virus (ISAV) are viruses causing threatening diseases in Norwegian aquaculture. Certainly, one of the most challenging problems in designing control strategies against these viruses is to define the specific factors, both in...

Awarded: NOK 12.0 mill.

Project Period: 2008-2011

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Aleström Zebrafish Lab - activities beyond the research projects 2007-2011

The major focus of the AZLab services are two-fold: 1) Being a regional center, in an national and international network of transgenic zebrafish laboratories, with capacity to offer access to the zebrafish model for academic and commercial partners. 2) Es tablish a unique training program in zebr...

Awarded: NOK 4.5 mill.

Project Period: 2008-2012

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Translational Research in Lung Cancer and Palliative Care - from genomics to symptom control

This project will perform functional genomic research with a translational approach that will bring new scientific knowledge into the health care system. The project will identify gene polymorphisms and gene expression profiles that may confer developmen t of lung cancer, and act as a prognostic...

Awarded: NOK 9.3 mill.

Project Period: 2008-2012

Location: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

Oslo Animal MRI unit - a node in the FUGE NorMIC consortium

The MR technology now allows for in vivo imaging to a resolution of microns which is even less than the size of many cell types. MRI has therefore become an invaluable tool for molecular imaging and translational research. Scientists in Oslo have used the FUGE MIC animal MR unit in Trondheim unt...

Awarded: NOK 1.00 mill.

Project Period: 2008-2012

Location: Ukjent Fylke

FUGE-Funksjonell genomforskn.i Norg

Spontaneous preterm birth: a systems biology approach in the Norwegian Mother and Child Cohort Study

sPTB is an unresolved common complex condition in perinatal medicine and is related to long-term disabilities such as cerebral palsy, cognitive and respiratory problems, which will affect the infant in every day life situations. The pathophysiology of sPT B remains poorly understood. Infection an...

Awarded: NOK 15.0 mill.

Project Period: 2008-2012

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

A novel checkpoint regulating the cell cycle of fission yeast

In this project we shall further study and characterise a novel mechanism of checkpoint regulation that we have recently discovered (Tvegård et al, Genes Dev, 2007). Checkpoints are important regulators of the cell cycle. Cancer development is frequently associated with the lack of checkpoints an...

Awarded: NOK 5.3 mill.

Project Period: 2008-2011

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Norwegian Molecular Imaging Consortium - Subnode: Subcellular interactions and imaging - NTNU

Knowledge about protein-protein interactions as well as interactions between other molecules is of critical importance for functional genomics. By providing the state-of-the-art technologies to study inter-and intramolecular interactions, the national res earch community will be able to move func...

Awarded: NOK 7.4 mill.

Project Period: 2008-2013

Location: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

Local NOR-MIC BioImaging node at the University of Tromsø

At the University of Tromsø we now establish a core facility for BioImaging. This core facility will be equipped with instruments aimed at imaging, flow cytometri, cell sorting and plate/membrane readers of fluorescent and chemiluminescent signals. For th is core facility we will have two full-ti...

Awarded: NOK 0.45 mill.

Project Period: 2008-2012

Location: Troms - Romsa - Tromssa

FUGE-Funksjonell genomforskn.i Norg

The Proteomics Core Facility at the University of Tromsø as a node in the national consortium of proteomics platforms (NorProteomics)

The core facility for Proteomics in Tromsø has been fully operational since the end of 2004. The main purpose of the facility has been to serve research labs in the FUGE North region. The facility has 3 Mass spectrometer systems from Waters/Micromass. A M ALDI Micro MX, a Q-TOF Ultima Global with...

Awarded: NOK 1.3 mill.

Project Period: 2008-2012

Location: Troms - Romsa - Tromssa

FUGE-Funksjonell genomforskn.i Norg

Norwegian Proteomics Consortium - Bergen

PROBE, the Norwegian proteomic platform, was established in 2002 by the Norwegian Research Council under the Functional Genomics Initiative (FUGE) to provide the Norwegian scientific community access to the best in proteomic technologies and competence. Located within the Institute of Biomedicine...

Awarded: NOK 9.5 mill.

Project Period: 2008-2012

Location: Vestland

FUGE-Funksjonell genomforskn.i Norg

A FUGE Nor-MIC Node in Live Cell Imaging and Protein-Protein Interaction Analysis in Plants

There is a growing need to understand fundamental plant processes at the subcellular level. With respect to this it is of paramount importance to the Norwegian research community that a National Imaging Service and Training facility exists to meet these f uture demands. In addition a Molecular Im...

Awarded: NOK 1.0 mill.

Project Period: 2008-2012

Location: Rogaland

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