20 projects

Date from new to old

TEKNOLOGIKONVER-TEKNOLOGIKONVER

Integrated convergent technology for precision human tissue and disease modeling

Advancing the study and treatment of disease is being accelerated by integrating and converging different types of technologies. Combining the use of patient-specific stem cells, innovative materials and micro/nanotechnology to create laboratory models of diseases has shown particular promise. Ef...

Awarded: NOK 15.0 mill.

Project Period: 2025-2029

Location: Oslo

FRIPROSJEKT-FRIPROSJEKT

Unlocking molecular diversity in the brain-to-body gateway: spatial transcriptomics and proteomics of brainstem-to-spinal cord projections

Packed with an intricate assembly of neurons and circuits serving vital functions (motor, respiratory, cardiovascular, hormonal regulation, temperature and pain regulation, sleep) the brainstem is the LEAST expendable part of the brain. These multiple, critical functions are mediated by a large p...

Awarded: NOK 9.6 mill.

Project Period: 2023-2027

Location: Oslo

HELSEVEL-H-Gode og effektive helse-, omsorgs- og velferdstjenester

National Stem Cell and Regenerative Medicine Conference

Stem cell and regenerative medicine research in Norway is being carried out at multiple research and clinical institutions, and there is a strong need to provide a national forum in which researchers, clinicians, patient groups and health policy makers can meet to interact and network. This proje...

Awarded: NOK 0.15 mill.

Project Period: 2018-2019

Location: Oslo

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Non-invasive electrical stimulation of the cervical spinal cord to facilitate arm and hand functional re plasticity after spinal cord injury

Spinal cord injury typically causes permanent loss of sensory and motor functions. But some limited functional recovery can occur through a process called adaptive plasticity, and much current research is focused on how to promote this. In this project, we are focusing on adaptive plasticity in t...

Awarded: NOK 4.7 mill.

Project Period: 2017-2020

Location: Oslo

FRIMED2-FRIPRO forskerprosjekt, medisin og helse

Targeted perturbation of perineuronal nets in specific neuron types to investigate adaptive plasticity after spinal cord injury

Spinal cord injury typically causes permanent loss of sensory and motor functions. But some limited functional recovery can occur through a process called adaptive plasticity, and much current research is focused on how to promote this. A key issue is the molecular basis of adaptive plasticity, h...

Awarded: NOK 11.3 mill.

Project Period: 2016-2020

Location: Oslo

STAMCELLER-Stamcelleforskning

Stamceller - Nettverksmøte 2015, 2016, 2017

The Norwegian Center for Stem Cell Research organises the Annual Norwegian Stem Cell Networking Meeting at Soria Moria Hotel & Conference Center outside of Oslo. The meeting brings together Center core group members and associate members, non-Center stem cell researchers who had received funding ...

Awarded: NOK 0.73 mill.

Project Period: 2015-2017

Location: Oslo

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Norwegian Center for Stem Cell Research 2014-2018

This application lays out a strategic plan for the Norwegian Center for Stem Cell Research for the period 2014-2018. The Center has therefore developed a four-pronged strategy with 2 translational and 2 basic science arms, with the following areas of emph asis: Clinical trials using human somat...

Awarded: NOK 26.1 mill.

Project Period: 2014-2021

Location: Innlandet

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Patient-derived iPS cells for investigating pathogenetic mechanisms of brain diseases that cause movement disorders

The general aim of the proposed project is to develop iPS cell-based platforms for elucidating disease mechanisms in monogenic neurological diseases. Specifically, the project focuses on monogenic neurological diseases affecting parts of the brain involved in motor function, and which thus cause ...

Awarded: NOK 4.2 mill.

Project Period: 2013-2020

Location: Oslo

IS-DAAD-Forskerutveksling Norge-Tyskland

Dissecting the developing vestibulo-ocular reflex circuit: Pharmacogenetic and optogenetic manipulation

A fundamental question in neuroscience is how neuronal circuits are assembled during embryonic and fetal development. Critical features include the establishment of functionally appropriate patterns of synaptic connections and a proper balance between exc itatory and inhibitory connections. Senso...

Awarded: NOK 34,661

Project Period: 2011-2013

Location: Oslo

STAMCELLER-Stamcelleforskning

Production of hESCs for the study of human serotonergic neurons in health and disease

The neurotransmitter serotonin, one of the key modulatory neurotransmitters, is pivotally involved in myriad of neurological and behavioral disorders, including migraine, motor disorders, sleep disorders, eating disorders, and a spectrum of neuropsychiatr ic disorders including major depression, ...

Awarded: NOK 3.0 mill.

Project Period: 2010-2014

Location: Oslo

STAMCELLER-Stamcelleforskning

Neural patterning of the mammalian forebrain - in vitro generation of Hippocampal neurons from mouse and human ES cells.

The mammalian forebrain develops from a sheet of neuroepithelium that is flanked by distinct patterning centers. The Hippocampus, a part of the brain of crucial function for perception, memory and learning - which is disproportionally affected in diseases such as Alzheimers and epilepsy, arise f...

Awarded: NOK 0.46 mill.

Project Period: 2010-2016

Location: Oslo

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Molecular labels that instruct specific synapse formation

One of the major questions within the field of Molecular Neuroscience is how different neurons are able to locate and form synapses specifically with their appropriate targets so that functional neural circuits are generated. Two quite different mechanis ms appear to be involved. One is an activ...

Awarded: NOK 42,999

Project Period: 2009-2009

Location: Oslo

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Nasjonalt stamcelleforskningssenter i Helse Sør-Øst RHF - se også prosjektnr 230000 hvor midler for ny periode ligger.

The Norwegian Center for Stem Cell Research was established in 2009 at the Oslo University Hospital-National Hospital (Rikshospitalet) through a directive from the Norwegian Ministry of Health, with funding administered by the Norwegian Research Council. The center's principal objectives have ...

Awarded: NOK 34.3 mill.

Project Period: 2008-2019

Location: Innlandet

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Non-invasive in vivo imaging of neural stem cells

Stem cell biology is one of the most closely followed developments in biomedicine today, since stem cells may provide the foundation for rational regenerative therapeutics with far-reaching implications in the health sector. The use of stem cells to gener ate new nerve cells has received particul...

Awarded: NOK 3.1 mill.

Project Period: 2007-2011

Location: Oslo

IS-AUR-Samarb.progr. mellom Norge og Frankrike

Glover, Joel Aur06-07

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Awarded: NOK 53,221

Project Period: 2006-2008

Location: Oslo

IS-DAAD-Forskerutveksling Norge-Tyskland

Glover, Joel C DAADppp-06

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Awarded: NOK 40,000

Project Period: 2006-2006

Location: Oslo

FRIBIO-Biologi og biomedisin

Molecular characterization of embryonic microenvironment that stimulates adult human hematopoietic stem cells to differentiate into neurons

Recent research from the applicant and colleagues has shown that adult human hematopoietic stem cells, derived from bone marrow biopsies, can be stimulated to differentiate into nerve cells by placing them into the injured spinal cord of a chicken embryo. The injured embryonic spinal cord regen...

Awarded: NOK 2.9 mill.

Project Period: 2006-2009

Location: Oslo

BIOFYS-Fysiologiske og anatomiske fag

Emergence of functional neural networks in the developing brain: A functional imaging study

The current view of brain development is that neuronal circuits are formed through an interaction between two fundamentally different mechanisms. First, growing axons are targeted to specific regions by molecular guidance and recognition cues. Second, on going neuronal activity regulates the str...

Awarded: NOK 1.3 mill.

Project Period: 2005-2006

Location: Oslo

BIOFYS-Fysiologiske og anatomiske fag

Descending control of the neural circuitry controlling walking in mammals

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Awarded: NOK 0.76 mill.

Project Period: 2004-2006

Location: Oslo

BIOFYS-Fysiologiske og anatomiske fag

Optical recording of electrical activity in developing neural circuits

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Awarded: NOK 1.6 mill.

Project Period: 2002-2005

Location: Oslo