2 projects

NANOTEKNOLOGI-NANOTEKNOLOGI

A novel nanotopography-based approach for reshaping nuclear morphology and gene transcription

The cell nucleus functions as the control center of the cell and plays a critical role in how cells respond to physical forces from their surrounding environment. However, our understanding of these responses remains incomplete due to a lack of tools to manipulate cells and their nuclei. To addre...

Awarded: NOK 10.0 mill.

Project Period: 2024-2027

Location: Oslo - Oslove

FRIPROSJEKT-FRIPROSJEKT

URGE-3D: Unraveling new gene dysregulation modules in cancer through integrated multi-constraint 3D genome modeling

DNA is organized in three dimensions (3D) within the cell nucleus. This organization is crucial for regulating gene expression and maintaining normal cell function. However, our understanding of the relationship between the 3D organization of DNA and cellular function is very limited and needs to...

Awarded: NOK 8.0 mill.

Project Period: 2021-2026

Location: Oslo - Oslove