0 projects

Date from new to old

KOSK-II-Katalyse og org.synt.kjemi II

Design and optimisation in organic synthesis: Methodologies for the optimisation of multi-step one-pot batch processes

Assume tha a three step one-pot reaction is tt be optimised: Lay out a design to map the first step. Depending on how detailed information is desired, this can be a fractional factorial, factoral, D-optimal, or a response surface design for quardratic m odels. Run the experiments and detrmine t...

Awarded: NOK 1.8 mill.

Project Period: 2007-2009

Location: Troms - Romsa - Tromssa

KOSK-II-Katalyse og org.synt.kjemi II

Theory-assisted design of functional group-tolerant catalysts for olefin conversion

The goal of the project is to design new transition-metal complexes with a reactivity that is highly selective for the alkene double bond function. The selectivity will be exploited in the development of functional group tolerant catalysts for an importan t class of olefin refinement process: Ole...

Awarded: NOK 3.9 mill.

Project Period: 2007-2011

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

Carbocation mediated hydrocarbon reactions over acidic zeotype catalysts

Acid catalysis over zeotype materials is one of the most important and fundamental topics in catalysis. Basic natural gas conversion processes like MTO (methanol to olefins), dimerisation, and C4 isomerisation can be performed using acid catalysis by zeol ites and/or microporous SAPOs. In additio...

Awarded: NOK 3.1 mill.

Project Period: 2007-2010

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Organisk Kjemisk Vintermøte 2007

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Awarded: NOK 40,885

Project Period: 2007-2007

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Structure-Activity Relationship and Binding Mode for Cyclopentapeptide Antagonists of CXCR4, a Therapeutic Target in HIV/AIDS and Oncology

The main physiological role of the human G-protein coupled chemokine receptor CXCR4 and its natural ligand SDF-1a is homing of leukocytes and embryonic development. However, CXCR4 has also been shown to be involved in the pathology of several serious dise ases, most notably AIDS (HIV entry point ...

Awarded: NOK 2.9 mill.

Project Period: 2009-2013

Location: Troms - Romsa - Tromssa

KOSK-II-Katalyse og org.synt.kjemi II

The state of rhenium in cobalt-rhenium Fischer-Tropsch catalysts

Kobolt baserte Fischer-Tropsch katalysatorer får høyere aktivitet dersom de promoteres med en liten mengde av et annet metall. Det kan være edelmetaller som Pt, Re, men ogs rimeligere alternativer som Ni. Dette prosjektet søker å finne ut mer om interaksjonene mellom kobolt og promotoren i kataly...

Awarded: NOK 2.9 mill.

Project Period: 2009-2014

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Design and optimisation in organic synthesis:Optimisation of telscope reactions and methodologies base on orthogonal experiments

Telescope reactions: Assume that a three-step reaction is to be optimised: Lay out a statistical design to map the first step. Run the experiments an determine the responses. The response matrix Y=[y1 y2 ....ur] summarises the results. A principal compone nt model will determine the number of ind...

Awarded: NOK 2.8 mill.

Project Period: 2009-2013

Location: Troms - Romsa - Tromssa

KOSK-II-Katalyse og org.synt.kjemi II

Det 23. Organisk-Kjemisk Vintermøte 2008

The Organic Winter Meeting is the national meeting in organic chemistry in Norway. It is a conference under the umbrella of the Norwegian Chemical Society, which has given me the task to organize the meeting. Since its infancy the tradition has been to invite 3-4 eminent chemists, covering vari...

Awarded: NOK 49,999

Project Period: 2008-2008

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

Design and synthesis of novel aspartic protease inhibitors.

This project will focus on the development of much needed novel inhibitors of the aspartic proteases related to HIV/AIDS and Alzheimers disease. In order to pursue these goals, the project seeks to establish a strong research group in medicinal chemistry at the Centre for Pharmacy at the Universi...

Awarded: NOK 2.3 mill.

Project Period: 2008-2012

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

Synthesis of novel activators for procaspase-3: an approach to a personalised cancer treatment

Cancer is an important public health concern around the world. Chemotherapy is no doubt one of the most successful ways in which cancer can be treated. For years, chemotherapy has been indiscriminate warfare by using chemotherapeutic agents that are toxic to both normal and cancer cells. In this...

Awarded: NOK 1.7 mill.

Project Period: 2008-2010

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Advanced Characterisation of Local Coordination of T-atoms in Microporous Materials with CHA Topology

The Catalysis group at the Department of Chemistry, University of Oslo and the Department of Hydrocarbon Process Chemistry at SINTEF Materials and Chemistry have been collaborating fruitfully for decades, and during the last 10 years they have exploited t he synergy between experimental and compu...

Awarded: NOK 2.1 mill.

Project Period: 2009-2013

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Norsk Katalysesymposium 23.-24. oktober 2007

Katalysesymposiet er Faggruppa for katalyse (Norsk kjemisk selskap) sitt viktigste arrangement. Faggruppas medlemmer er spredt over hele Norge, og samles bare til årsmøtet og katalysesymposiet som dermed får en viktig nasjonal faglig funksjon. Symposiet f ungerer tradisjonelt også som årsmøte for...

Awarded: NOK 29,999

Project Period: 2007-2007

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Quantum modelling studies of local coordination of T-atoms in zeolites

Aluminosilicate zeolites are solid acids that may act as catalysts for various reactions, such as the conversion of methanol to light alkenes. Recent NMR results obtained in a joint project between UiO and the group of Prof. Francis Taulelle in Versailles , France, give new insight into the local...

Awarded: NOK 1.9 mill.

Project Period: 2010-2013

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Synthesis of resolvin D1 and analogs as potential anti-angiogenetic agents

Epidemiological studies have linked fat fish consumption to lower rates of several diseases such as cancer and Alzheimer's disease. Fish contains high levels of omega-3 polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid and docosahexaenoic acid. Recently, the potential efficacy of...

Awarded: NOK 1.9 mill.

Project Period: 2011-2013

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Design and synthesis of chiral aminophosphonates: from biomimetic catalysis to phosphapeptides

Awarded: NOK 1.8 mill.

Project Period: 2011-2015

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Fundamental understanding of the controlling factor for the C5+ selectivity for Co/CNF catalysts in Fischer Tropsch synthesis

Fischer-Tropsch synthesis is one of the key processes in natural gas conversion. Enormous efforts have been devoted to increase C5+ selectivity. However, a detailed understanding of elementary steps leading to chain growth is still missing. The project a ddresses identification of important fact...

Awarded: NOK 1.9 mill.

Project Period: 2011-2013

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Novel carbenoid chemistry

Halogenation reactions are of great practical importance within the field of synthetic organic chemistry, and halogenated molecules can have highly advantageous biological properties. For instance, fluorinated and chlorinated molecules are frequently enco untered both in drug design and among nat...

Awarded: NOK 2.8 mill.

Project Period: 2010-2014

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

MICROPEP II - Design and synthesis of antimicrobial peptides targeted against pathogenic fungi.

Radiation treatment of head and neck cancer must be suspended due to Candida infection in the mouth and throat. This is just an example showing the need for new treatment of fungal infections. The present project addresses these issues by proposing to ide ntify pharmacophores for antimicrobial ac...

Awarded: NOK 4.0 mill.

Project Period: 2007-2011

Location: Troms - Romsa - Tromssa

KOSK-II-Katalyse og org.synt.kjemi II

Catalytic dehydrogenation of NGL components. Application of in situ spectroscopic techniques for studying dehydrogenation catalysts.

Catalytic dehydrogenation of NGL is a vital process for the production of olefins. Typically, Cr-oxide or Pt-based catalysts are used for commercial processes. The project focuses on the application of operando and in situ spectroscopic studies of Cr-oxid e based catalysts during dehydrogenation ...

Awarded: NOK 0.83 mill.

Project Period: 2007-2009

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Synthesis Directed towards Development of Potential Antituberculosis Drugs with Novel Mechanism of Action

Tuberculosis (TB) is the major cause of death from a single infectious agent among adults in developing countries. Human immunodeficiency virus (HIV) infections have further increased TB morbidity and mortality. It has been estimated that ca. 30 million p eople will die from tuberculosiswithin th...

Awarded: NOK 3.7 mill.

Project Period: 2007-2011

Location: Oslo

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