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KOSK-II-Katalyse og org.synt.kjemi II

The 28th Organic Chemistry Winter Meeting

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Awarded: NOK 70,655

Project Period: 2013-2014

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

Organisk Kjemisk Vintermøte, Skeikampen 12.-15. januar 2012

The 27th Organic Winter Meeting will take place January 12th-15th 2012 at Thon Hotel Skeikampen. This conference is the national meeting in organic chemistry in Norway, and it is held under the umbrella of the Division of Organic Chemistry of the Norwegia n Chemical Society. Since the initiation ...

Awarded: NOK 26,264

Project Period: 2012-2012

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Fundamental understanding of the controlling factor for the C5+ selectivity for Co/CNF catalysts in Fischer Tropsch synthesis

Fischer-Tropsch synthesis is one of the key processes in natural gas conversion. Enormous efforts have been devoted to increase C5+ selectivity. However, a detailed understanding of elementary steps leading to chain growth is still missing. The project a ddresses identification of important fact...

Awarded: NOK 1.9 mill.

Project Period: 2011-2013

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Synthesis of resolvin D1 and analogs as potential anti-angiogenetic agents

Epidemiological studies have linked fat fish consumption to lower rates of several diseases such as cancer and Alzheimer's disease. Fish contains high levels of omega-3 polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid and docosahexaenoic acid. Recently, the potential efficacy of...

Awarded: NOK 1.9 mill.

Project Period: 2011-2013

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Fundamental understanding of catalyst nanoparticles by atomic scale chemical imaging

Fundamental study down to the atomic level is crucial for improving our understanding of catalysts and enhancing our ability for their rational design. The present project deals with exploring advanced TEM techniques such as aberration corrected microscop y and environmental TEM for imaging of co...

Awarded: NOK 2.8 mill.

Project Period: 2011-2013

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Design and synthesis of chiral aminophosphonates: from biomimetic catalysis to phosphapeptides

Awarded: NOK 1.8 mill.

Project Period: 2011-2015

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Gold catalysis and new chiral NHC compounds.

Gold catalysis of organic reactions has become a rapidly expanding field in recent years after being neglected by organic chemists for a long time. Gold catalysts react in very selective ways and may give access to highly complex molecules. The present p roject describes the continued investigat...

Awarded: NOK 1.8 mill.

Project Period: 2011-2013

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Synthesis, molecular modelling and biological evaluation of protectin D1 and analogs

Inntak av omega-3-fettsyrer som eicosapentaensyre (EPA) og docosaheksaensyre (DHA) har i flere studier vist å gi positive helseeffekter. Disse omega-3-fettsyrene finnes i tran og fet fisk. De eksakte molekylære årsakene til disse positive helseeffektene e r ennå ikke klarlagt. Ny forskning utfø...

Awarded: NOK 2.8 mill.

Project Period: 2010-2014

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Quantum modelling studies of local coordination of T-atoms in zeolites

Aluminosilicate zeolites are solid acids that may act as catalysts for various reactions, such as the conversion of methanol to light alkenes. Recent NMR results obtained in a joint project between UiO and the group of Prof. Francis Taulelle in Versailles , France, give new insight into the local...

Awarded: NOK 1.9 mill.

Project Period: 2010-2013

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Novel carbenoid chemistry

Halogenation reactions are of great practical importance within the field of synthetic organic chemistry, and halogenated molecules can have highly advantageous biological properties. For instance, fluorinated and chlorinated molecules are frequently enco untered both in drug design and among nat...

Awarded: NOK 2.8 mill.

Project Period: 2010-2014

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Gold catalysis and new chiral NHC ligands.

Gold catalysis of organic reactions has become a rapidly expanding field in recent 5 years after being neglected by organic chemists for a long time. Gold complexes are less oxophilic than other common Lewis acids, but they are highly reactive as Lewis a cids towards carbon-carbon multiple bonds...

Awarded: NOK 0.91 mill.

Project Period: 2010-2011

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Det 25. Organisk Kjemiske Vintermöte

Dessa vintermöten anordnas varje år av Norsk Kjemisk Selskap. Ansvaret för arrangangen roterar mella lärosätena i Norge och vid vilka en huvudansvarig utses.För år 2010 är det undertecknad vid Univeritetet i Ttomsø som har fått detta ansvar. Med denna ans ökan begärs ett finansiellt stöd från NFR...

Awarded: NOK 74,714

Project Period: 2010-2010

Location: Troms - Romsa - Tromssa

KOSK-II-Katalyse og org.synt.kjemi II

Norsk katalysesymposium 2009

Norsk katalysesymposium arrangeres i Trondheim 30.11. - 1.12.2009. Vertskap for arrangementet er katalysegruppa ved NTNU. Konferansen samler en stor andel av de som er aktive innen katalyse i Norge innen akademia og instituttsektoren, samt sentrale aktøre r fra industrien. Symposiumet fungerer og...

Awarded: NOK 20,092

Project Period: 2009-2010

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

The state of rhenium in cobalt-rhenium Fischer-Tropsch catalysts

Kobolt baserte Fischer-Tropsch katalysatorer får høyere aktivitet dersom de promoteres med en liten mengde av et annet metall. Det kan være edelmetaller som Pt, Re, men ogs rimeligere alternativer som Ni. Dette prosjektet søker å finne ut mer om interaksjonene mellom kobolt og promotoren i kataly...

Awarded: NOK 2.9 mill.

Project Period: 2009-2014

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Advanced Characterisation of Local Coordination of T-atoms in Microporous Materials with CHA Topology

The Catalysis group at the Department of Chemistry, University of Oslo and the Department of Hydrocarbon Process Chemistry at SINTEF Materials and Chemistry have been collaborating fruitfully for decades, and during the last 10 years they have exploited t he synergy between experimental and compu...

Awarded: NOK 2.1 mill.

Project Period: 2009-2013

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Engineering of Pt nanoparticles in Propane Dehydrogenation

Nanocrystals with well controlled size, shape and surface composition provides excellent opportunities not only in fundamental study of heterogeneous catalysis but also for improving existing catalysts or design new catalysts for chemical processes. Porpa ne dehydrogenation is a conventional chem...

Awarded: NOK 2.4 mill.

Project Period: 2009-2012

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Design and optimisation in organic synthesis:Optimisation of telscope reactions and methodologies base on orthogonal experiments

Telescope reactions: Assume that a three-step reaction is to be optimised: Lay out a statistical design to map the first step. Run the experiments an determine the responses. The response matrix Y=[y1 y2 ....ur] summarises the results. A principal compone nt model will determine the number of ind...

Awarded: NOK 2.8 mill.

Project Period: 2009-2013

Location: Troms - Romsa - Tromssa

KOSK-II-Katalyse og org.synt.kjemi II

Quantum chemical modelling of metal-support interactions in metal-based catalysts

Production of synthesis gas (carbon monoxide and hydrogen) is a process of major importance for chemical upgrading of natural gas. In this process, a catalyst consisting of metal clusters supported on an oxide surface is used. The project's main challenge will be to elucidate the role of strong ...

Awarded: NOK 1.7 mill.

Project Period: 2008-2011

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Fundamental understanding of novel Co catalysts on carbon nanofibers in F-T synthesis

It has been found that the CNFs are promising as supports to achieve high activity and selectivity due to their mesoporous structure, high mechanical strengths, high surface areas. More importantly, it was found that the activity and selectivity of F-T ca talysts depends significantly on the Co c...

Awarded: NOK 1.3 mill.

Project Period: 2008-2010

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Synthesis of novel activators for procaspase-3: an approach to a personalised cancer treatment

Cancer is an important public health concern around the world. Chemotherapy is no doubt one of the most successful ways in which cancer can be treated. For years, chemotherapy has been indiscriminate warfare by using chemotherapeutic agents that are toxic to both normal and cancer cells. In this...

Awarded: NOK 1.7 mill.

Project Period: 2008-2010

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

C-H Activation reactions at neutral cyclometalated Pt complexes

The Tilset group has made important contributions towards selective C-H activation and functionalization at platinum complexes in solution and, recently, in development of novel Pt-containing metal-organic frameworks that may be of interest for catalytic applications. One drawback (this applies t...

Awarded: NOK 1.7 mill.

Project Period: 2008-2010

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Synthetic studies directed towards asmarines and other purines with fused heterocyclic systems

Nature is a rich source of bioactive compounds and potential drugs. The so-called secondary metabolites are structures involved in interaction between organisms, for instance chemical defense. Studies of such metabolites have led to the discovery of many life-saving drugs, including antibiotics, ...

Awarded: NOK 2.3 mill.

Project Period: 2008-2012

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Design and synthesis of novel aspartic protease inhibitors.

This project will focus on the development of much needed novel inhibitors of the aspartic proteases related to HIV/AIDS and Alzheimers disease. In order to pursue these goals, the project seeks to establish a strong research group in medicinal chemistry at the Centre for Pharmacy at the Universi...

Awarded: NOK 2.3 mill.

Project Period: 2008-2012

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

Rare-Earth Metal-Promoted C-H Bond Activation

The production of valuable chemicals via selective functionalization of saturated and unsaturated hydrocarbons is a major challenge in the field of contemporary organometallic chemistry. A particularly attractive substrate is methane which has previously been successfully C-H bond activated by ...

Awarded: NOK 1.7 mill.

Project Period: 2008-2010

Location: Vestland

KOSK-II-Katalyse og org.synt.kjemi II

MICROPEP II - Design and synthesis of antimicrobial peptides targeted against pathogenic fungi.

Radiation treatment of head and neck cancer must be suspended due to Candida infection in the mouth and throat. This is just an example showing the need for new treatment of fungal infections. The present project addresses these issues by proposing to ide ntify pharmacophores for antimicrobial ac...

Awarded: NOK 4.0 mill.

Project Period: 2007-2011

Location: Troms - Romsa - Tromssa

KOSK-II-Katalyse og org.synt.kjemi II

Synthetic applications of nitropyridine derivatives.

A number of substituted 3-nitropyridines are now easily available by a new nitration method, and some of these derivatives are suitable substrates for the preparation of a series of bis-heterocycles. We will investigate the chemistry of nitropyridyl deriv atives further and propose to utilise 3-n...

Awarded: NOK 3.9 mill.

Project Period: 2007-2012

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Integrated process for hydrogen production with CO2 capture using sorption enhanced reactions

Hydrogen production from natural gas with CO2 capture is of strategic importance in Norway. The project deals with a new technology using sorption enhanced reactions enabling to produce hydrogen form natural gas in one-step with CO2 capture. The multifunc tional reactor combines pre-reforming, me...

Awarded: NOK 2.3 mill.

Project Period: 2007-2013

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Partial Oxidation of Methane. Studies on mechanism and kinetics.

Synthesis gas can be produced by catalytic partial oxidation using gas phase oxygen. However, this process is facing some major engineering problems such as the presence of large temperature gradients and the risk of explosion caused by premixed methane a nd oxygen. An alternative approach is to ...

Awarded: NOK 2.2 mill.

Project Period: 2007-2011

Location: Trøndelag - Trööndelage

KOSK-II-Katalyse og org.synt.kjemi II

Catalysis with Pd Complexes that have Chelating N-Heterocyclic Carbene Ligands

The Tilset research group has recently developed the first members of a new class of chelating ligands, iminocarbenes, that form well-defined homogeneous Pd complexes with hemilabile, 5- and 6-membered, chelate structures. The use of these Pd complexes in the catalytic transformation of organic ...

Awarded: NOK 2.2 mill.

Project Period: 2007-2010

Location: Oslo

KOSK-II-Katalyse og org.synt.kjemi II

Synthesis Directed towards Development of Potential Antituberculosis Drugs with Novel Mechanism of Action

Tuberculosis (TB) is the major cause of death from a single infectious agent among adults in developing countries. Human immunodeficiency virus (HIV) infections have further increased TB morbidity and mortality. It has been estimated that ca. 30 million p eople will die from tuberculosiswithin th...

Awarded: NOK 3.7 mill.

Project Period: 2007-2011

Location: Oslo

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