249 projects

Date from new to old

HELSEFORSKNING-Helseforskning

ANeED Joint Effort 21: eHealth and a PPI-program in Dementia with Lewybodies (DLB)

Digital Signatures from Wearable Devices in Dementia with Lewy Bodies Dementia with Lewy bodies is the second most common cause of dementia and a disease that affects many different organs in the body, in addition to the brain, where it causes cognitive impairment in the form of reduced mental s...

Awarded: NOK 16.0 mill.

Project Period: 2021-2027

Location: Vestland

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Frampeik 2022 – Forskerlinjestudentenes største konferanse

Frampeik er en årlig forskningskonferanse arrangert av frivillige medisinstudenter fra forskerlinjene tilknyttet Universitetene i Trondheim, Oslo, Tromsø og Bergen. Ansvaret for konferansen rullerer mellom studiestedene, og i år ønsker forskerlinjestudenter fra Oslo å invitere til Frampeik 2022 –...

Awarded: NOK 0.11 mill.

Project Period: 2021-2022

Location: Vestland

HELSEFORSKNING-Helseforskning

Home monitoring of pregnancies at risk

The main aims of the HOME study (Home monitoring of pregnancies at risk) are to assess if home monitoring of maternal health and fetal heart rate patterns of selected high-risk pregnancies is feasible, safe, cost-efficient, and simultaneously empowers the users. In Norway, despite excellent pre...

Awarded: NOK 16.0 mill.

Project Period: 2021-2027

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Computational modelling and functional validation platform for personalised colorectal cancer clinical therapy decision support (ONCOLOGICS)

It is a well-known challenge for society, the health service, and unfortunately also for individuals, that many patients receive cancer treatment that only works for the few. This entails high personal costs - survival, quality of life, side effects - and significant societal costs - expensive me...

Awarded: NOK 4.1 mill.

Project Period: 2021-2026

Location: Trøndelag - Trööndelage

HELSEFORSKNING-Helseforskning

Long-term health effects of COVID-19 - the Norwegian Corona Cohort

Three months after the first wave of COVID-19 in Norway, in the summer of 2020, more than 100,000 participants in the Corona Study ("Koronastudien.no") responded to a questionnaire in which we asked how they felt. We were surprised that so many of those who had had COVID reported that their healt...

Awarded: NOK 7.4 mill.

Project Period: 2021-2025

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Artificial Intelligence for Diagnosing Retinal Diseases

Blindness tremendously affects the quality of life of the patients. Treating and helping patients that suffer from diseases that lead to vision loss results in huge economic costs for society. Two major diseases that involve the light sensitive neural tissue at the back of the eye (the retina) ar...

Awarded: NOK 2.6 mill.

Project Period: 2021-2024

Location: Vestfold

HELSEFORSKNING-Helseforskning

Covid-19 and impact on mental health: a longitudinal, multi-national study (C-Me)

The corona pandemic represents the largest global health crisis of this century. Although Norway so far has successfully limited spread of the virus, the mitigating factors and the general stress amidst the pandemic may have affected the population’s mental health. There is an urgent need for res...

Awarded: NOK 12.0 mill.

Project Period: 2021-2026

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Preventing multimorbidity in severe mental disorders with a multidisciplinary approach

The main objective of the project is to improve preventative measures of comorbid cardiovascular disease (CVD) risk in patients with severe mental disorders (SMD; i.e. schizophrenia, bipolar disorders and severe depression), by evaluating interventions targeting the modifiable life-style risk fac...

Awarded: NOK 15.7 mill.

Project Period: 2021-2026

Location: Trøndelag - Trööndelage

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Sustainable development in healthcare and science: The NORdic DOCtoral (NorDoc) education conference 2022

Since the publication of the Brundtland report, 1987 Norway has had a central role in leading the focus group promoting and mobilising efforts for realising the United Nations 2030 sustainable development goals. NorDoc 2022 Summit is needed to engage young, next generation scientists to commit th...

Awarded: NOK 0.28 mill.

Project Period: 2021-2023

Location: Vestland

HELSEFORSKNING-Helseforskning

AI for new signatures and models for tailored organ preservation approaches in laryngeal and hypopharyngeal cancer

Locally advanced voice box lower throat cancer may be treated with induction chemotherapy, potentially followed by radiotherapy for voice box preservation, as an alternative to total excision of the voice box. However, not all patients benefit from this strategy, and up to 30-40% have a total exc...

Awarded: NOK 3.1 mill.

Project Period: 2021-2026

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

OrChid -Oral health care services for Children victims of violence and sexual abuse -Focusing on the clinical forensic dental examinations

The United Nations Convention on the Rights of the Child states that every child has a right to education, play, health, and to protection from violence and exploitation. In spite of this promise, violence and child abuse have become a major public health and welfare problem in high-income countr...

Awarded: NOK 8.7 mill.

Project Period: 2021-2026

Location: Østfold

HELSEFORSKNING-Helseforskning

Preventing an Opioid Epidemic In Norway: Focusing on Treatment of Chronic pain (POINT)

Patients with chronic pain need good treatment. The use of opioids for chronic, non-malignant pain may seem appropriate in the short term, but can often have negative consequences for both the individual and society in the long term. In addition, there is a lack of a robust knowledge base showing...

Awarded: NOK 16.0 mill.

Project Period: 2021-2026

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Implementation of Patients Safety Checklist (PASC) in Surgery, a Stepped Wedge Cluster RCT - Effects on Patient and Implementation Outcomes

Building on the Norwegian Patient Safety Program target areas, the Patients Surgical Checklist (PASC) aims to empower patient involvement in patient safety collaborative and to prevent patient harm in the surgical pathway. By using the checklist patients actively prepare themselves for the operat...

Awarded: NOK 12.4 mill.

Project Period: 2021-2026

Location: Vestland

HELSEFORSKNING-Helseforskning

Oral health in adults: predictors, social gradients and correlation with cardiovascular health in women and men

A number of diseases are increasing in incidence due to reasons such as increased life expectancy, poor diet and lifestyle. Oral cavity diseases such as caries and gum disease (periodontitis) belong to this group together with cardiovascular disease, among other things. A connection between disea...

Awarded: NOK 16.0 mill.

Project Period: 2021-2026

Location: Vestland

HELSEFORSKNING-Helseforskning

Tactile sensory impairment of C-LTMR afferents in preterm children

Gentle touch is an important part of maternal care: it comforts, calms, and enables regulation of arousal in newborns. A special group of nerve fibers is crucial for humans - like other mammals - to perceive and enjoy slow, pleasant stroking. These are called C-LTMR nerve fibers. This project has...

Awarded: NOK 4.2 mill.

Project Period: 2021-2025

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

#Care4YoungTeeth<3

The #Care4YoungTeeth<3 project set out to improve dental health among all adolescents, regardless of their social, geographic, or economic background. Over the past 30 years, dental health among children and youth in Norway has improved significantly. Still, a substantial proportion of 18-year-ol...

Awarded: NOK 16.0 mill.

Project Period: 2021-2026

Location: Trøndelag - Trööndelage

HELSEFORSKNING-Helseforskning

Depressive disorder in primary care – an integrated solution for improving treatment and preventing severe outcome

Depressive disorder is a prevalent psychiatric condition associated with significant disability, mortality and economic burden for society. Given this tremendous disease burden, there is an urgent need for efficient and individualized treatments. We want to develop an efficient treatment and prev...

Awarded: NOK 16.0 mill.

Project Period: 2021-2027

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Tailoring the targeted treatment of chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in Europe and it remains incurable. Targeted therapies have revolutionized the treatment of CLL. However, many patients achieve a suboptimal response. To prevent ineffective treatment and toxic effects, there is an unmet clini...

Awarded: NOK 4.1 mill.

Project Period: 2021-2026

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Precision drugs Against Resistance In Subpopulations

In high-grade serous ovarian cancer (HGSOC) there is an urgent medical need for effective treatment options for the patients with a limited response to both standard chemotherapy and emerging PARP inhibitors. Apart from the mutations in DNA repair pathways, targetable point mutations in tumour su...

Awarded: NOK 3.0 mill.

Project Period: 2021-2026

Location: Vestland

HELSEFORSKNING-Helseforskning

Defining stratification of patients with C3G/IC-MPGN complex mediated glomerular diseases for better diagnosis and tailored treatment

Primary membranoproliferative glomerulonephritis represents a group of rare kidney disorders associated with complement activation. There is no specific therapy and the prognosis is unfavorable: about half of all patients, mostly children, develop end-stage renal disease and need dialysis within ...

Awarded: NOK 2.8 mill.

Project Period: 2021-2025

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Precision therapy versus standard therapy in Acute Myeloid Leukaemia and Myelodysplastic syndrome in elderly (PALM) – a randomized trial

Acute myeloid leukemia (AML), severe myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) in the elderly have poor prognosis because the patients do not tolerate curative treatment with high doses of chemotherapy or stem cell transplantation. Patients therefore receive treatm...

Awarded: NOK 12.0 mill.

Project Period: 2020-2028

Location: Akershus

HELSEFORSKNING-Helseforskning

Personalised rehabilitation of stroke patients evaluated with multimodal quantitative tools

In this project we aim to understand the relationship between the parameters determining neuroplastic changes after stroke so that we can we can best promote functional outcome. Armed with such knowledge, we hope to be able to tailor rehabilitation of stroke patients to achieve a higher level of...

Awarded: NOK 12.0 mill.

Project Period: 2020-2026

Location: Trøndelag - Trööndelage

HELSEFORSKNING-Helseforskning

Quantifying systemic immunosuppression to personalize cancer therapy

The immune system is now considered to contribute to the effect of most cancer therapies. Some immune cells appear to be beneficial, while other immune cells may mediate resistance to therapy and promote cancer growth. The focus of this project, is to study the role of an immune cell type consid...

Awarded: NOK 2.9 mill.

Project Period: 2020-2025

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Strategies towards personalised medicine in Juvenile Idiopathic Arthritis; the MyJIA project

Juvenile idiopathic arthritis (JIA) is a chronic inflammatory joint disease that may cause damage and disability in childhood. New drugs and treatment strategies, notably tumour necrosis factor (TNF)-inhibitors have ameliorated symptoms in JIA, although the majority of them do not reach a state o...

Awarded: NOK 11.8 mill.

Project Period: 2020-2027

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Optimizing management of musculoskeletal pain disorders in primary care (SUPPORTPRIM)

Musculoskeletal (MSK) disorders are among the most widespread health issues globally and the leading cause of disability. These conditions place a significant burden on both patients and society. Traditional treatments for MSK disorders often lack solid evidence or provide only moderate and short...

Awarded: NOK 12.0 mill.

Project Period: 2020-2025

Location: Trøndelag - Trööndelage

HELSEFORSKNING-Helseforskning

A multiomics approach towards personalized medicine in rheumatoid arthritis

Rheumatoid arthritis is a multifactorial disease where the underlying biology and clinical features vary between patients. Current clinical treatment depends on trial-and-error, and it may take time to find the optimal treatment regimen for an individual patient. A likely reason for the variation...

Awarded: NOK 11.1 mill.

Project Period: 2020-2026

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

EU-COVID-19 - a multinational registry-based linkage study with focus on risk and protective factors, clinical outcomes and mental health.

EU-COVID-19 - a multinational registry-based linkage study with focus on risk and protective factors, clinical outcomes and mental health The aim of this international interdisciplinary project is to provide knowledge about the populations' risk factors and health consequences of COVID-19. An ad...

Awarded: NOK 2.3 mill.

Project Period: 2020-2023

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

XR-Naltrexone for opioid addiction: the importance of mental, physical and societal factors for longer term and post treatment recovery

Opioid addiction has several negative consequences, including the risk of overdose deaths, for the users, their families and the society. Treatment is the most effective factor to prevent such negative consequences and to promote recovery processes. Opioid users are a heterogeneous group and the...

Awarded: NOK 7.0 mill.

Project Period: 2020-2025

Location: Akershus

HELSEFORSKNING-Helseforskning

Repurposing in personalized leukemia therapy

Repurposing existing medicines for treatment of acute myeloid leukemia (AML) Acute myeloid leukemia (AML) is an aggressive form of blood cancer that mainly affects older adults. The average age at diagnosis is around 70 years, and among people over 60, there are about 17 new cases per 100,000 ea...

Awarded: NOK 12.0 mill.

Project Period: 2020-2027

Location: Vestland

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Supporting Personalized Treatment Decisions in Head and Neck Cancer through Big Data

Head and Neck Carcinomas (HNC) are aggressive and heterogeneous tumors with a high fatality rate. Treatment may be extremely invasive and its impact on quality of life can be devastating. Neither molecular sub-classification nor prognostic models are well established in clinical practice, because...

Awarded: NOK 2.9 mill.

Project Period: 2020-2024

Location: Oslo - Oslove

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