0 projects

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Hurtige utsorteringsmetoder for råneslakt

Det er vedtatt i Stortinget at kastrering av gris ikke lenger vil være tillatt i Norge fra 2009. Problemet knyttet til produksjon av ukastrert hanngris er at en betydelig andel av slaktene vil være beheftet med uønsket rånelukt og rånesmak. Denne egenskap en er i hovedsak knyttet til slaktets inn...

Awarded: NOK 19.6 mill.

Project Period: 2004-2009

Location: Akershus

YFF-Yngre, fremragende forskere

Identification of phenotypes and genetic susceptibility in severe mental disorders

Severe mental disorders (schizophrenia and bipolar/manic-depressive disorder) are major causes of disability worldwide, and rank as some of the most costly disorders to afflict humans. The etiology still remains elusive, but there is now overwhelming evid ence that genetic factors play a prominen...

Awarded: NOK 8.3 mill.

Project Period: 2004-2010

Location: Oslo

KREFTSATS-Særutlysning kreftmidler, historikk

Genetic predictors of mammographic density

Mammographic density represents a strong and independent breast cancer risk factor, and possibly a useful surrogate endpoint for breast cancer risk. Mammographic density decreases when women undergo menopause or start tamoxifen therapy, but increases in w omen starting postmenopausal hormone ther...

Awarded: NOK 3.9 mill.

Project Period: 2004-2009

Location: Oslo

FRIBIO-Biologi og biomedisin

Functional genomics of the malaria parasite Plasmodium falciparum

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Awarded: NOK 2.1 mill.

Project Period: 2004-2010

Location: Troms - Romsa - Tromssa

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Genetics of boar taint

Male pigs used for pork production are normally castrated very early in life to prevent boar taint or sex taint in the meat. However, castration will be prohibited in the near future and a major challenge for the pig production industries in the next 5-10 years is to decrease the boar taint in m...

Awarded: NOK 23.2 mill.

Project Period: 2004-2010

Location: Innlandet

FUGE-Funksjonell genomforskn.i Norg

Knockout zebrafish (KO-ZFISH) model

The genome projects – from microorganisms to vertebrates and mammals – create huge amounts of undeciphered genetic information. This cumulated DNA sequence bank needs intelligent, but as simple as possible, model systems to turn the currency of genomics into functional genomics. Only in one ver...

Awarded: NOK 11.0 mill.

Project Period: 2004-2009

Location: Akershus

NANOMAT-Nanoteknologi og nye materialer

Nytt pulver nøytron diffraktometer - PUS 2

Pulver nøytrondiffraksjon er en sentral metode for strukturundersøkelser av funksjonelle materialer og nanomaterialer. Det er et stort behov for et nytt pulver nøytron diffraktometer, PUS 2, øremerket for in-situ og tidsoppløste studier i tillegg til det eksisterende høyoppløsningsinstrumentet PU...

Awarded: NOK 5.0 mill.

Project Period: 2004-2010

Location: Akershus

KREFTSATS-Særutlysning kreftmidler, historikk

Critical regulatory networks for tumor-vascular interactions and activated angiogenesis in urogenital cancers

Angiogenesis and tumor-vascular interactions are essential for tumor spread. We focus on this aspect since anti-angiogenic therapy avoid treatment resistance. Adhesion molecules are important for the ability of tumor cells to invade surrounding tumor stro ma and to enter the vascular systems (blo...

Awarded: NOK 6.6 mill.

Project Period: 2004-2009

Location: Vestland

KREFTSATS-Særutlysning kreftmidler, historikk

Developmental biology of solid tumours may pave the way for advanced medicine

We study three human cancer diseases, colorectal cancer (CRC), testicular germ cell tumour (TGCT), and malignant peripheral nerve sheath tumour (MPNST), originating from different types of stem cells. All three diseases develop through morphologically def ined stages, and the stepwise molecular b...

Awarded: NOK 6.6 mill.

Project Period: 2004-2009

Location: Oslo

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Akrylamid i matvarer - betydning for reproduksjon

Det er nylig avdekket at akrylamid dannes ved varmebehandling av matvarer med høyt stivelsesinnhold. I dyrestudier er det vist at akrylamid gir svulster, binder seg til og skader arvestoffet, og gir reproduksjonsskader. Vi har foreløpig liten kunnskap om i hvilket omfang befolkningen eksponeres f...

Awarded: NOK 1.8 mill.

Project Period: 2004-2010

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Gene repair by oxidative demethylation

We have recently discovered a novel mechanism for repair of alkylation damage in DNA, performed by the E.coli AlkB protein, and also by human AlkB homologues. This repair function involves the demethylation of 1-methyladenine and 3-methylcytosine lesions discoveries have opened up many interest...

Awarded: NOK 6.9 mill.

Project Period: 2004-2009

Location: Oslo

FRIBIO-Biologi og biomedisin

Regulation of Protein Kinase C (PKC) membrane targeting and PKC-mediated activation of phosphatases

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Awarded: NOK 1.9 mill.

Project Period: 2004-2009

Location: Oslo

NANOMAT-Nanoteknologi og nye materialer

Metal Organic Chemical Vapour Deposition (MOCVD) for synthesis of complex oxides

The versatile equipment will serve several research activities. With respect to materials chemistry, MOCVD will be a crucial method for extending synthesis capabilities beyond the present deposition methods, in particular bridging the gap in film thicknes s that is provided by the ALCVD and sol-g...

Awarded: NOK 5.0 mill.

Project Period: 2004-2011

Location: Oslo

SAM-EU-Samfinansiering EU-kontoret

NANOCAPS - Nano- and microcapsules - effective delivery of chemicals for special targets (STREP)

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Awarded: NOK 0.79 mill.

Project Period: 2004-2010

Location: Trøndelag - Trööndelage

SAM-EU-Samfinansiering EU-kontoret

COMPOSE - Multicomponent nanostructured materials for separation membranes (STREP)

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Awarded: NOK 0.99 mill.

Project Period: 2004-2009

Location: Trøndelag - Trööndelage

HAVBRUKS-Havbruk - en næring i vekst

Function of Anti-Müllerian hormone in fish testis development and maturation to puberty

This project aims to determine the function of Anti-Müllerian hormone (AMH) in fish as a factor in testis determination, development, and maturation at puberty. AMH, also named Müllerian inhibiting substance or spermatogenesis preventing substance, belong s to the transforming growth factor-ß fam...

Awarded: NOK 7.4 mill.

Project Period: 2004-2010

Location: Vestland

SIP-NHD-Strategiske instituttprogram finansiert av NHD

RECON - Renewal of Concrete Infrastructure

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Awarded: NOK 11.0 mill.

Project Period: 2004-2009

Location: Nordland - Nordlánnda

KREFTSATS-Særutlysning kreftmidler, historikk

Opioids, Symptom Management and Palliation Research Group

The group was formally established in 2002 thanks to a research grant from Norwegian Research Council (NFR) (2001-2003). The group consist of core personnel in permanent positions at The Faculty of Medicine, NTNU and personnel supported by the above NFR grants and other grants including NFR. T...

Awarded: NOK 8.8 mill.

Project Period: 2004-2009

Location: Trøndelag - Trööndelage

SIP-NHD-Strategiske instituttprogram finansiert av NHD

DISvaDRI - Dispersoids In Steel and value added Direct Reduced Iron

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Awarded: NOK 13.8 mill.

Project Period: 2004-2009

Location: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

Nuclear program in health and disease - transcriptome approach to mechanisms

A central theme in the post-genomic era is to understand the fine-tuned symphony of gene expression. Transcription is the first and critical step of molecular events that turns the genome into a functional genome and weaves together target genes in coreg ulated cellular programs. In fact, many ...

Awarded: NOK 12.0 mill.

Project Period: 2004-2009

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Functional genomics studied by modern mass spectrometry

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Awarded: NOK 7.4 mill.

Project Period: 2004-2009

Location: Oslo

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Molekylærbiologiske studier av gram-positive bakterier: Funksjonell genomikk og anvendelse.

The overall goal of this project is to conduct fundamental research on lactic acid bacteria (LAB) and propionibacteria (PAB) and to exploit this research for the benefit of the food, medicinal and agricultural industry. To achieve this we will address the following four research themes, (1) meta...

Awarded: NOK 23.0 mill.

Project Period: 2004-2011

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Transgenic models in neuroscience: Uncovering the secrets of the hippocampal formation

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Awarded: NOK 8.0 mill.

Project Period: 2004-2009

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Protein-protein interactions between infectious pancras virus proteins and host protein

In the post-genomic area new approaches have been developed to study and characterize protein functions in cells and organisms. One such strategy is the yeast two-hybrid system that can be used to generate complete protein interactions maps. Infectious pancreatic necrosis is one o the most thre...

Awarded: NOK 7.4 mill.

Project Period: 2004-2009

Location: Troms - Romsa - Tromssa

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Endocrine disrupters (ED): Risk assessment for food quality and animal health

Akkumulering av hormonhermere i miljøet og overføring av disse stoffene til til dyr og mennesker er fokus for stadig større oppmerksomhet. Dette forskningsprogrammet retter oppmerksomheten mot dette problemkomplekset ved å undersøke mulige helseskadelige effekter ved biomakkumulering i vev som br...

Awarded: NOK 12.4 mill.

Project Period: 2004-2009

Location: Oslo

SIP-LMD-SIP finansiert av Landbruksog matdepartementet

Bakterielle utfordringer i oppdrett av marine arter

Norsk akvakultur opplever for tiden en fase med spesialisering og ekspansjon samtidig som infrastruktur og kompetanse innen bakteriologisk ekspertise i akvatisk bakteriologi i Norge er minimal for tiden. Det er grunn til å tro at bakterieinfeksjoner vil h indre utviklingen av en blomstrende marin...

Awarded: NOK 15.1 mill.

Project Period: 2004-2010

Location: Oslo

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Skrapesjuke Nor98

Den atypiske formen av skrapesjuke som betegnes Nor98-typen og som til nå er påvist i vel 20 besetninger i Norge synes å han en annen opptreden enn klassisk skrapesjuke. Sjukdommen representerer en stor utfordring både for næring og forvaltning. Gjennom d ette prosjektet tar en sikte på å fremska...

Awarded: NOK 15.7 mill.

Project Period: 2004-2009

Location: Akershus

HAVBRUKS-Havbruk - en næring i vekst

Development of recombinant oral vaccines using a bacterial carrier. Antigen expression in M. capsulatus.

We show that it is possible to express heterologous protein epitopes as parts of endogeneous surface proteins in M. capsulatus. M. cap. will be used as vehicle for antigen presentation and immunisation. We will characterise, using injection immunisation p rotocols in rabbit and fish, the immunoge...

Awarded: NOK 3.5 mill.

Project Period: 2004-2010

Location: Vestland

PROSBIO-Prosess- og biomedisinsk industri

Naturlige karotenoider fra mikroalger

Promar har utviklet en fotosyntes bioreaktor som i gjennomført forskning har demonstrert kommersielt svært interessante resultater. Via samarbeid med Dr Geir Johnsen ved NTNU Institutt for Biologi har Promar fått tilgang på en patenterbar oppfinnelse; Kar otenoidet diadinoxanthin er et fettløslig...

Awarded: NOK 8.0 mill.

Project Period: 2004-2009

Location: Akershus

SUP-NHD-Strategiske UoH-progr.fin.NHD

Smart Microsystems for Diagnostic Imaging in Medicine

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Awarded: NOK 14.7 mill.

Project Period: 2004-2010

Location: Trøndelag - Trööndelage