0 projects

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NEVRONOR-Nasjonal satsing på nevrovitenskap f

Norwegian PET Conference and Seminar Series

This application is for fundiing for conference and seminar series to develop the Positron emission tomography (PET) method into an important tool in the study of the Brain and Brain-derived human disease. It is based on the Norwegian Medical Cyclotron Ce nter (NMS) in Oslo and the Bergen PET Cen...

Awarded: NOK 0.30 mill.

Project Period: 2007-2009

Location: Oslo

FORNY-3-Kommersialisering av FoUresultater

Early diagnosis of diabetes

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Awarded: NOK 2.2 mill.

Project Period: 2007-2009

Location: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Computational models of aberrant attribution of salience in schizophrenia and the effects of medication: An event related fMRI study

It has been known for decades that dopamine abnormalities are relevant to the pathophysiology of schizophrenia (mainly psychotic symptoms) and that blocking the dopamine system is associated with improvements in symptoms. How one gets from this neurochemi cal change to the expressed behavior abno...

Awarded: NOK 2.5 mill.

Project Period: 2007-2012

Location: Oslo

FORNY-3-Kommersialisering av FoUresultater

New drugs for treatment of disorders associated with insulin resistance, such as type 2 diabetes and obesity

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Awarded: NOK 2.4 mill.

Project Period: 2007-2009

Location: Oslo

FORNY-3-Kommersialisering av FoUresultater

Construction of human monoclonal antibodies by the FRIDA-method: potential medical use against cancer and infectious diseases.

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Awarded: NOK 3.1 mill.

Project Period: 2007-2009

Location: Oslo

FRIMED-Klinisk medisin og folkehelse

Multi-modal imaging: The importance of fiber connections for cognitive function, brain activity and brain structure in research and clinic

The main objectives of this project are 1) integration of informations from different neuroimaging methods (diffusion tensor imaging [DTI], structural MRI, functional MRI [fMRI], event-related potentials [ERP]) and refined cognitive measures, 2) use these methods to understand the biological fou...

Awarded: NOK 2.4 mill.

Project Period: 2007-2011

Location: Oslo

S-AFRIKA-Program for forskningsamarbeid med Sør- Afrika

Nutritional intervention and novel diagnostics to improve community-based control of tuberculosis

Tuberculosis (TB) is a major public health problem in developing countries as well as in the Republic of South Africa (RSA). Despite significant strides in case detection and treatment, the prevalence of TB continues to rise at an alarming, also in the RS A. More effective diagnostic methods are ...

Awarded: NOK 0.29 mill.

Project Period: 2007-2010

Location: Vestland

FUGE-Funksjonell genomforskn.i Norg

Functional genomics and diabetes in Norway - Clinical, molecular, cellular and epidemiological analysis of monogenic diabetes

Diabetes is a common and severe disease. Maturity-onset diabetes of the young (MODY) is an inherited type of diabetes with decreased insulin secretion. Based on our national MODY Registry, we have recently identified a novel syndrome of exocrine and endoc rine pancreatic dysfunction caused by mut...

Awarded: NOK 8.5 mill.

Project Period: 2007-2012

Location: Ukjent Fylke

SFI-Sentre for forskningsdrevet innovasjon

Medical Imaging Laboratory

Sentre for forskningsdrevet innovasjon (SFI) er en nyskapning der flere industripartnere, universitet og sykehus arbeider sammen i et åpent forskningsmiljø. MI Lab var i stand til å skape et tverrfaglig miljø for åpen innovasjon og langsiktig industriell forskning med høy vitenskapelig kvalitet o...

Awarded: NOK 80.0 mill.

Project Period: 2007-2015

Location: Trøndelag - Trööndelage

SFI-Sentre for forskningsdrevet innovasjon

Tromsø Telemedicine Laboratory: Research-Based Innovation in Telemedicine and eHealth Systems for Chronic, Age, & Lifestyle related Diseases

TTL har i 2013 hatt rekordhøy vitenskapelig produksjon med 8 avlagte doktorgrader og et jevnt høyt antall vitenskapelige publikasjoner (36), proceedings (28) og bokkapitler (4). I tillegg er det 12 som skriver doktorgrad per i dag og som er i oppløpet . 2014 er det ventet et like høyt antall av...

Awarded: NOK 80.0 mill.

Project Period: 2007-2015

Location: Troms - Romsa - Tromssa

GLOBHELS-Global helse

Further Developments of New Immunogenic Peptide-based HIV Vaccines Targeting Dendritic Cells

Therapeutic HIV vaccines targeting dendritic cells have so far shown more promising results than preventive HIV vaccines and may become an alternative even for prophylaxis. This Proposal describes plans for basic clinical studies on further characterizati on and developments of new immunization s...

Awarded: NOK 7.4 mill.

Project Period: 2007-2013

Location: Oslo

GLOBHELS-Global helse

Preparing for tuberculosis vaccine efficacy trials: Baseline epidemiology, improved diagnosis, markers of protection and phase I/II trials

This collaboration between scientists in Denmark, India, Norway, South Africa and the U. S. will conduct 3 large cohort studies of tuberculosis (TB) in Palamaner, India, using state of the art immunology to identify correlates of protective immunity and i ncipient disease. These cohorts will be a...

Awarded: NOK 18.5 mill.

Project Period: 2007-2014

Location: Vestland

BIA-Brukerstyrt innovasjonsarena

Fotokjemisk internalisering for cellegiftterapi av kreft

PCI Biotech AS utvikler en patentert teknologi for levering av legemidler, kalt fotokjemisk internalisering (forkortet PCI). Sentralt i denne teknologien står en patentert kjemisk forbindelse, kalt TPCS2a, som PCI Biotech utvikler for utprøving i pasiente r i innledende kliniske studier i kombina...

Awarded: NOK 8.5 mill.

Project Period: 2007-2010

Location: Oslo

BIA-Brukerstyrt innovasjonsarena

Produksjon av solbeskyttende karotenoider fra bakterier.

Produksjon av solbeskyttende karotenoider fra bakterier. De fleste solkremer beskytter dårlig mot stråling ved 360-500 nm (langbølget UVA og synlig blått lys), selv om det i de senere år er blitt fokusert også på disse bølgelengdene i forbindelse med mela nom hudkreft, fotoaldring og andre solind...

Awarded: NOK 6.8 mill.

Project Period: 2007-2010

Location: Akershus

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Non-invasive in vivo imaging of neural stem cells

Stem cell biology is one of the most closely followed developments in biomedicine today, since stem cells may provide the foundation for rational regenerative therapeutics with far-reaching implications in the health sector. The use of stem cells to gener ate new nerve cells has received particul...

Awarded: NOK 3.1 mill.

Project Period: 2007-2011

Location: Oslo

NEVRONOR-Nasjonal satsing på nevrovitenskap f

The Norwegian Multiple Sclerosis Registry and Biobank

Multiple sclerosis (MS) is an immune-mediated, inflammatory disease of the central nervous system (CNS) in genetically susceptible individuals. It is a disabling disease of young adults, with no curable treatment available. There is growing knowledge of s everal aspects of the disease, but the et...

Awarded: NOK 4.5 mill.

Project Period: 2007-2010

Location: Vestland

FRIMED-Klinisk medisin og folkehelse

Exposure expression profiles in a prospective cancer study - The Norwegian Women and Cancer postgenome cohort

From 1991 women in Norway has been recruited to participate in NOWAC by postal questionnaires. They are drawn at random from the population through the central person register. Follow-up on cancer and death is based on linkage to national registers. Altog ether 150 000 women aged 30-70 years at r...

Awarded: NOK 1.6 mill.

Project Period: 2007-2010

Location: Troms - Romsa - Tromssa

NEVRONOR-Nasjonal satsing på nevrovitenskap f

High-resolution fMRI of the function of hippocampal subfields during encoding and retrieval of episodic memory in humans.

Research during past 50 years has firmly established the hippocampus as an essential structure for episodic and semantic memory. However, we know little about the function of the diverse hippocampal networks and subfields in memory formation. New evidence from our group at The Centre for the Bio...

Awarded: NOK 3.0 mill.

Project Period: 2007-2011

Location: Trøndelag - Trööndelage

BIA-Brukerstyrt innovasjonsarena

DualPET-MR

The main objective for this project is to develop dual-modality PET-MR for molecular biology and medicine which will allow for the combined and simultaneous use of positron emission tomography (PET) and magnetic resonance (MR). In such a combined machine the PET provides information from molecula...

Awarded: NOK 5.1 mill.

Project Period: 2007-2009

Location: Oslo

FRIMED-Klinisk medisin og folkehelse

THE HORDALAND WOMEN'S COHORT STUDY. A planned 15-year (1997-2012) follow up incidence study of urinary incontinence, and associated factors

Urinary incontinence (UI) is a common condition with a prevalence of about 25% of adult women, that affects the physical, psychosocial, and economic well-being. Longitudinal studies of incidence, remission and natural history are scarce. The Hordaland wo men's cohort study is an ongoing 15-year ...

Awarded: NOK 2.5 mill.

Project Period: 2007-2011

Location: Vestland

GLOBHELS-Global helse

New rotavirus vaccines: targeting childhood morbidity and mortality in low- and middle-income countries in Central Asia

The current project is aimed at reducing morbidity and mortality caused by rotavirus (RV) disease among young children in low- and middle-income countries in Central Asia. RV is the most common cause of severe acute gastroenteritis in young children and a major cause of childhood death in develo...

Awarded: NOK 8.8 mill.

Project Period: 2007-2012

Location: Oslo

BIA-Brukerstyrt innovasjonsarena

A new Computed Tomography (CT) detector with color/dual-energy features and substantially reduced patient X-ray dose

Computed Tomography (CT) is one of the most important medical diagnosis tools of today. World-wide there is a waste number of installations, a strong increase in sales, and it represents consequently a big industry for the manufacturers. The X-ray detecto r in the CT is the main part of the machi...

Awarded: NOK 6.3 mill.

Project Period: 2007-2010

Location: Oslo

FRIMED-Klinisk medisin og folkehelse

Gene-environment interaction analyses and oral clefts in Norway

Norway has several large epidemiological studies with genetic bio-banks that may be used in etiologic research. Examples are the CONOR-cohort and the MoBa-cohort of children with mothers and fathers. Optimal analysis of such studies requires integration o f both genetic and environmental effects....

Awarded: NOK 2.8 mill.

Project Period: 2007-2011

Location: Vestland

FRIMED-Klinisk medisin og folkehelse

Psychosocial effects and understanding of increased risk for Type 1 Diabetes

With the rapid development in biotechnology and increasing knowledge about the relation between diseases and genetic variability, we are faced with both new opportunities and new dilemmas. Onset of a disease is dependent on several factors as genetic pene trance, combinations of genotypes and env...

Awarded: NOK 2.8 mill.

Project Period: 2007-2010

Location: Oslo

FRIMED-Klinisk medisin og folkehelse

Physical activity level, determinants of physical activity, physical fitness, fatness and health in Norwegian children

INTRODUCTION: The obesity epidemic in the Western World is well known, and even if the prevalence of obesity in Norway is much lower than in countries such as USA and England body weight has increased in Norwegian children during the last decades. Althoug h weight gain is a consequence of higher ...

Awarded: NOK 0.38 mill.

Project Period: 2007-2010

Location: Oslo

FRIMED-Klinisk medisin og folkehelse

Pregnancies and cancer risk - a prospective study based on Norwegian register data

In this project, associations between pregnancies and cancer risk will be examined. Focus will be on cancer forms known to be hormone-related, and also on some cancer types with less evidence for being susceptible to hormonal exposure. Our study is based on information from the Population registe...

Awarded: NOK 2.3 mill.

Project Period: 2007-2010

Location: Vestland

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Cell-specific brain imaging with viral vectors

Modern brain imaging methods have contributed enormously to contemporary knowledge about the particular brain systems involved in specific cognitive functions. Unfortunately, mechanistic insights have lagged behind, largely because brain mapping in humans lacks the spatial resolution required to...

Awarded: NOK 3.0 mill.

Project Period: 2006-2009

Location: Trøndelag - Trööndelage

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Mother's neurological disease as a risk factor for the child

The neurological diseases myasthenia gravis (MG), multiple sclerosis (MS) and epilepsy can influence pregnancy, the process of giving birth and the child. Genetic factors, pathogenic mechanisms, disease symptoms and therapy can be responsible. The Medical Birth Registry of Norway contains inform...

Awarded: NOK 2.2 mill.

Project Period: 2006-2010

Location: Vestland

PSYKISK-Psykisk helse

Major depression, cognitive function and cortisol

Our knowledge of the relationships between depression, cortisol levels and daily cortisol profiles, and cognitive impairment in a long-term perspective is scant. We aim to study these relationships over two years in patients with MDD diveded in to subgrou ps of patients with a first time episode,...

Awarded: NOK 3.0 mill.

Project Period: 2006-2014

Location: Vestland

BIA-Brukerstyrt innovasjonsarena

Ultralyd i lommeformat - Fremtidens stetoskop

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Awarded: NOK 15.2 mill.

Project Period: 2006-2011

Location: Vestfold

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