249 projects

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Supporting Personalized Treatment Decisions in Head and Neck Cancer through Big Data

Head and Neck Carcinomas (HNC) are aggressive and heterogeneous tumors with a high fatality rate. Treatment may be extremely invasive and its impact on quality of life can be devastating. Neither molecular sub-classification nor prognostic models are well established in clinical practice, because...

Awarded: NOK 2.9 mill.

Project Period: 2020-2024

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Survival rates and long-term outcomes for patients with COVID-19 admitted to Norwegian ICUs

The study Survival rates and long-term outcomes for patients with COVID-19 admitted to Norwegian ICUs has two different aims. The first aim was to synthesis data from a National register (Norwegian Intensive care-and Pandemic register) on all COVID-19 patients in Norway admitted to an ICU. Resu...

Awarded: NOK 2.6 mill.

Project Period: 2020-2022

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Defining the immune cells in COVID-19 that correlate with disease severity

The RCN research grant allowed us to start COVID-19 work, to establish regional and National networks and to secure the first Norwegian grant from the international coalition for preparedness against pandemics and for vaccine development, CEPI (The Coalition for Epidemic Preparedness Innovations)...

Awarded: NOK 1.6 mill.

Project Period: 2020-2023

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

IMAGINE: Imaging molecular mechanisms of angiogenesis in glioma-associated neovasculature

Glioblastoma is one of the deadliest forms of cancer, and there is an urgent and unmet need to improve treatment strategies. A significant challenge is that glioblastomas are heterogeneous; therefore future treatment advances must be tailored to each patients’ unique and specific molecular featur...

Awarded: NOK 12.0 mill.

Project Period: 2020-2025

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

B-cell immunosuppresion or pulsed immune reconstitution therapy as Efficient and Active Treatment for Multiple Sclerosis

Multiple sclerosis (MS) is a demyelinating and neurodegenerative inflammatory disease of the central nervous system, affecting more than 13 000 patients in Norway and more than 2.2 mill patients worldwide. Oral cladribine is one of the first choices for highly efficient disease modulatory treatm...

Awarded: NOK 11.9 mill.

Project Period: 2020-2027

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

STROKE RISK PREDICTION IN ATHEROSCLEROSIS MEASURING CIRCULATING COMPLEMENT SYSTEM PROTEINS

Stroke is a major public health burden, causing 5.5 million deaths annually worldwide and causing a significant percentage of patients with disability. New treatments have improved survival, but an increasing number of people survive with permanent disability, especially for the young. Consequent...

Awarded: NOK 2.9 mill.

Project Period: 2020-2025

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

National multi-centre study: a urine-based test for improved management of bladder cancer patients

The initiation of this national multi-center study was delayed due to the Covid-19 pandemic, and patient recruitment also proceeded more slowly than planned. We acknowledge the Research Council’s approval of an extended project period, with milestones adjusted to September 2026. The first milest...

Awarded: NOK 12.0 mill.

Project Period: 2020-2026

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

BEtablocker Treatment After Acute Myocardial Infarction in Patients Without Reduced Left Ventricular Ejection Fraction (BETAMI)

Beta-blockers have long been the standard treatment following a heart attack, but the evidence supporting their use is based on studies conducted in the 1980s. Since then, the diagnosis and treatment of heart attacks have changed considerably. For example, most heart attacks today are treated wit...

Awarded: NOK 11.9 mill.

Project Period: 2020-2026

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Prediction of antipsychotic drug response; a personalised medicine approach in schizophrenia

Psychiatric disorders constitute a significant burden for those affected, in addition to imposing substantial costs on the healthcare system in Norway and worldwide. Current treatment options are not effective for everyone, and many struggle with side effects. Furthermore, a trial-and-error appro...

Awarded: NOK 12.0 mill.

Project Period: 2020-2026

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Exercised Plasma to Treat Alzheimers Disease, The ExPlas Study

Does the key to preventing and treating Alzheimer’s lie in the blood of those who exercise? This question forms the basis of our research project, which seeks to explore new opportunities for developing medicines that can prevent, delay, and/or treat Alzheimer’s disease – the most common form of ...

Awarded: NOK 13.9 mill.

Project Period: 2020-2026

Location: Trøndelag - Trööndelage

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Bidrag til NordForsk utlysningen nordic health data reserch project on COVID-19

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Awarded: NOK 5.3 mill.

Project Period: 2020-2020

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Avslutningskonferanse ERANet-LAC CODE-prosjektet

Søknaden gjelder avslutningskonferansen for prosjektet ERANet-LAC CODE (Care Of the Dying Evaluation): «Pårørendes vurdering av omsorgen til døende kreftpasienter i sykehus». Dette er et treårig prosjekt 2017-2020, med deltakende forskergrupper fra Argentina, Brasil, Uruguay, Polen, Tyskland, Sto...

Awarded: NOK 0.15 mill.

Project Period: 2019-2019

Location: Vestland

HELSEFORSKNING-Helseforskning

Better treatment for Acute Sinusitis In primary health Care - BASIC

Antibiotic resistance is a major and growing problem. The use of antibiotics increases the risk of resistance occurring. It is therefore important to keep the use of antibiotics low, and not to use antibiotics unnecessarily. The respiratory infection most often treated with antibiotic tablets in ...

Awarded: NOK 15.0 mill.

Project Period: 2019-2026

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Norwegian Vision in Stroke (NorVIS) network

Vision is the most important human sense, and vision problems are common after stroke. In Norway 11-12 000 suffer a stroke every year, and more than half will experience a vision problem. Vision problems are associated with increase in falls, reduced outcomes of rehabilitation, quality of life an...

Awarded: NOK 5.0 mill.

Project Period: 2019-2026

Location: Buskerud

HELSEFORSKNING-Helseforskning

Enhanced cryoimmunotherapy against urogenital cancers

Dendritic cells (DCs) are central coordinators of the immune system. They detect foreign antigens - from bacteria, viruses, or aberrant cancer cells - and present them to lymphocytes. This instruction is essential: without DCs, lymphocytes cannot mount a targeted attack on cancer cells that conta...

Awarded: NOK 16.3 mill.

Project Period: 2019-2025

Location: Vestland

HELSEFORSKNING-Helseforskning

The Norwegian trial of Physical Exercise After Myocardial Infarction - NorEx

Regular physical activity is recommended both to prevent cardiovascular disease in healthy persons and to prevent recurrence or worsening among people already affected by such diseases. However, the scientific evidence for these recommendations is weak and based on observational data, and in real...

Awarded: NOK 20.0 mill.

Project Period: 2019-2026

Location: Trøndelag - Trööndelage

HELSEFORSKNING-Helseforskning

INTEGRATE 2019 Nasjonal konferanse om arbeidsinkludering og samhandling mellom tjenester, Lillehammer, 4-5 november 2019

INTEGRATE er et kjerneforskningsmiljø som skal utvikle forskning om hvordan samhandling mellom velferdstjenestene og mellom tjenestene og arbeidslivet kan fremme inkluderingen av vanskeligstilte grupper i arbeidsmarkedet. Kjerneforskningsmiljøet er et samarbeid mellom OsloMet-Storbyuniversitetet...

Awarded: NOK 0.15 mill.

Project Period: 2019-2025

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Impact of Molecular Point-of-Care Testing on Improved Diagnosis, Treatment and Management of CAP in NORWAY: a pragmatic RCT

Community-acquired pneumonia (CAP) remains a leading cause of hospital admission and death in older adults. A core problem is diagnostic delay: clinicians start broad-spectrum antibiotics before they know the culprit microbe, which can fuel antimicrobial resistance and expose patients to side eff...

Awarded: NOK 14.9 mill.

Project Period: 2019-2027

Location: Vestland

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Implementation of Stress and Adversity Inventory i multidisciplinary assessment of patients with obesity at Akershus University Hospital.

The purpose of this pilot project was to implement a validated method for stress assessment at the Outpatient clinic for morbid obesity at Ahus. During the project period, education and training should be carried out using the online questionnaire, Stress and Adversity Inventory for Adults (STRAI...

Awarded: NOK 0.20 mill.

Project Period: 2019-2020

Location: Akershus

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Improved Treatments of Acute Myeloid Leukaemias by Personalised Medicine

AML remains to cause 12,000 deaths each year in the EU. Without understanding how to upfront distinguish responders from non-responders, treatment is non-effective with many side effects, costly and challenging for the EUR reimbursement systems. In the AML_PM project, we have built infrastructure...

Awarded: NOK 3.9 mill.

Project Period: 2019-2023

Location: Vestland

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Improved precision medicine by increasing self-management and medication control in adolescents

Long term medical treatment of adolescent patients with chronic disease is challenging and non-adherence is common. Currently non-adherence is the major cause of reduced graft survival in adolescent (age 16-25 years) solid organ transplants. Improving adherence in this group of patients will be i...

Awarded: NOK 4.5 mill.

Project Period: 2019-2024

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

EpilepsiNett - Nasjonalt nettverk for evidensbasert epilepsiomsorg

Epilepsy is one of the most common disorders affecting the central nervous system. Epilepsy affects all age-groups, including children and youth. Living with epilepsy often means living without knowing when the next seizure will occur. It also means living with other people's insecurity and anxie...

Awarded: NOK 4.7 mill.

Project Period: 2019-2025

Location: Buskerud

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Den nasjonale helseøkonomikonferansen 2019

Det har vært mulig å arrangere konferansene gjennom en årlig bevilgning på 200 000 fra Forskningsrådet. Det er gitt bevilgning til og med 2018. Vi tror fortsatt det er behov for en konferanse som tar utgangspunkt i forskning og som konsentrerer seg om helseøkonomisk forskning. Samtidig er det stø...

Awarded: NOK 0.15 mill.

Project Period: 2019-2020

Location: Vestland

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Traume, Dissosiasjon og Psykosekonferansen 2019

I løpet av de siste årene har det vært en økende interesse for hvordan barndomstraumer kan utgjøre en viktig sårbarhetsfaktor for ulike psykiske lidelser, inkludert psykoselidelser. I 2015 ble den første internasjonale Traume, Dissosiasjon og Psykosekonferansen avholdt i Kristiansand. Denne ble e...

Awarded: NOK 0.17 mill.

Project Period: 2019-2020

Location: Agder

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

1th Symposium of Nordic Cardio-Oncology Society

Kreftinsidensen øker betydelig. Moderne diagnostikk og behandling har ført til at den generelle 5-års overlevelsen for kreft har økt fra ca 45% til nå i overkant av 70%. Baksiden er senvirkninger den moderne kreftbehandlingen kan gi. En slik senvirkning er hjerteskade. Det er større risiko for ka...

Awarded: NOK 75,100

Project Period: 2019-2020

Location: Akershus

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Improved personalized medicine through machine learning in mental disorders (IMPLEMENT)

Psychotic disorders are severe mental illnesses with early onset, frequently chronic course and often lifelong impairment. As a consequence, they cause an enormous healthcare burden, costing close to 100 billion euro annually in Europe alone. The biology of these illnesses is insufficiently under...

Awarded: NOK 2.9 mill.

Project Period: 2019-2023

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Personalized Medicine: From Systems medicine and Immunometabolism to Precision Diagnosis and Stratification for Individualized Therapies

Necrotizing soft tissue infections are rare, acute bacterial infections that spread in connective tissue, muscle tissue or fat tissue. In colloquial speech, such conditions are often called "flesh-eating bacterial infections". The infections are severe, with mortality between 15 and 25%. Prompt s...

Awarded: NOK 2.9 mill.

Project Period: 2019-2023

Location: Vestland

HELSEFORSKNING-Helseforskning

Targeting Aging and improving patient outcome with Nicotinamide Riboside

Can a vitamin shorten hospital stays after severe illness? After a severe acute illness, many patients experience a long and demanding recovery period. Even when the acute phase is over, it can take weeks or months for the body to regain its strength. This period is often marked by fatigue, redu...

Awarded: NOK 8.4 mill.

Project Period: 2019-2025

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Online psychosocial support for young people distressed by appearance-altering conditions: A randomised control trial (RCT)

Looking different in a society that values appearance can be challenging, especially during adolescence. Many different conditions can affect appearance, such as for example a craniofacial condition such as a syndrome or a cleft lip and palate, skin conditions, or acquired conditions such as a bu...

Awarded: NOK 9.8 mill.

Project Period: 2019-2024

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Optimizing Migraine Prevention (OptMig project)

Migraine is a chronic neurological disorder characterized by attacks of pulsating, often unilateral headaches that worsen with physical activity. The condition is often accompanied by sensitivity to light and sound, as well as nausea and/or vomiting, and it worsens with physical activity. Patient...

Awarded: NOK 15.0 mill.

Project Period: 2019-2025

Location: Trøndelag - Trööndelage