0 projects

FUGE-Funksjonell genomforskn.i Norg

ISVLV conference - Functional Genomics of Virus and Host interactions in infection and immunity in lower vertebrates

The International Symposium on Viruses of Lower Vertebrates (ISVLV) have been arranged six times since 1988. The 7th symposium will be arranged in Oslo, Norway in April 22-25, 2007 at the campus of the Norwegian School of Veterinary Science and the Nation al Veterinary Institute. Studies on ind...

Awarded: NOK 0.11 mill.

Project Period: 2007-2007

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Innovation Norway Life Sciences brochure

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Awarded: NOK 49,999

Project Period: 2007-2007

Location: Ukjent Fylke

FUGE-Funksjonell genomforskn.i Norg

A study of aging in the honey bee brain

The honey bee is a key neurobiological model for understanding learning and memory formation. As a highly social invertebrate, moreover, the bee provides unique opportunities for cutting-edge research on aging and frailty because it opens up the interface between the individual and the social en...

Awarded: NOK 7.0 mill.

Project Period: 2007-2010

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Early stage drug discovery on rheumatoid arthritis and glomerulonephritis

Prof. Berit Johansens research group at the Norwegian University for Technology and Science in Trondheim, Norway, has successfully uncovered the molecular cellular mechanism of pro-inflammatory lipid hormones as regulators of the inflammatory and immunolo gically important transcription factor NF...

Awarded: NOK 6.7 mill.

Project Period: 2007-2009

Location: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

USE OF SNP-CHIPS AND SELECTIVE DNA POOLING FOR IDENTIFYING DISEASE RESISTANCE MARKERS IN ATLANTIC SALMON

The main objective of this project is to find molecular markers that can be implemented in a marker assisted selection program (MAS) to increase genetic resistance to infectious salmon anaemia (ISA) in the Norwegian Atlantic salmon breeding program. MAS h as a great potential to increase the rate...

Awarded: NOK 2.4 mill.

Project Period: 2007-2010

Location: Vestland

FUGE-Funksjonell genomforskn.i Norg

Development of a cancer therapy using lytic peptidomimetics

Lytix Biopharma AS (Lytix) works with small synthetic peptides / peptidomimetica derived from primary amino acid sequences from Lactoferrin and that selectively kills cells by disrupting cell membranes. This application for grant concerns the use of the se peptides within cancer treatment where...

Awarded: NOK 13.3 mill.

Project Period: 2007-2009

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Protein aggregation and degradation in aging and disease: Role of polyubiquitination and autophagy

Hundreds of proteins encoded by the human genome have the propensity to form cytoplasmic aggregates under certain conditions. Although the mechanisms of intracellular protein aggregation are poorly understood, it is well known that deposits of aggregatete d proteins are highly associated with agi...

Awarded: NOK 8.6 mill.

Project Period: 2007-2011

Location: Ukjent Fylke

FUGE-Funksjonell genomforskn.i Norg

Development of gene therapeutic approaches for rheumathoid arthritis using in vivo gene delivery by photochemical internalisation (PCI)

Gene therapy has a large potential for treatment of many different diseases. The potential of gene therapy has, however, yet to be realised, mainly due to the lack of safe and efficient methods for delivery of therapeutic genes to diseased tissues in the body. It has recently been shown that PCI ...

Awarded: NOK 5.4 mill.

Project Period: 2007-2009

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Functional genomics of phenotypic plasticity of cod: a national consortium.

The proposed project is submitted by the University of Oslo as such (through its rector) on behalf of the other members in the consortium consisting of strong basic research groups with a strong and long experience within the fields of genomics, ecology a nd evolutionary biology. Although we repr...

Awarded: NOK 9.0 mill.

Project Period: 2007-2012

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

NucPro: Epigenetics of nuclear programs - from genome-wide landscapes to individual factor mechanisms

This Proposal outlines research plans for global epigenetic and transcription factor studies at an already established Functional Genomics (FUGE) Consortium for studies of nuclear programs at the University of Oslo (UiO). The consortium is a joint effort from four independent research groups to e...

Awarded: NOK 11.0 mill.

Project Period: 2007-2011

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

AlgiPharma activities supplementary to the Celltor project "Immune stimulating responses of biopolymers for the treatment of chronic wounds"

The Celltor-AlgiPharma project will be supplementary to sub-goals I-V in the Celltor project at NTNU. The AlgiPharma activities will be performed by AlgiPharma/FMC Biopolymer at AlgiPharma/FMC Biopolymers laboratories in Drammen/Oslo Research Park. Bioact ive candidate alginates and wound healing...

Awarded: NOK 1.5 mill.

Project Period: 2007-2009

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Vitenskapskafeen Oslo 2007

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Awarded: NOK 49,999

Project Period: 2007-2007

Location: Ukjent Fylke

FUGE-Funksjonell genomforskn.i Norg

Proposal for a National consortium in Fish Genomics - FishGen

The present proposal describes the establishment of a National Consortium in fish genomics (FishGen). The main partners in the FishGen are; Institute of Marine Research (IMR), University of Bergen (UoB), National institute of nutrition and seafood researc h (NIFES), University of Tromsø (UiTø), N...

Awarded: NOK 14.0 mill.

Project Period: 2007-2010

Location: Vestland

FUGE-Funksjonell genomforskn.i Norg

Detection, characterization and differentiation of infectious pancreatic necrosis virus (IPNV) strains in farmed Atlantic salmon

IPN outbreaks are seen both in the freshwater and seawater phase of the production, resulting in severe annual losses, and has emerged as a severe threat to the economy of the fish-farming industry. According to recent estimates, the yearly losses due to IPN in Norway are NOK 1 billion. This pro...

Awarded: NOK 3.5 mill.

Project Period: 2007-2010

Location: Møre og Romsdal

FUGE-Funksjonell genomforskn.i Norg

Characterization of Piscirickettsia salmonis infection and technology development for optimal vaccines against intracellular fish pathogens

Piscirickettsiosis caused by the intracellular bacterium P.salmonis has been shown to cause mortalities up to 90 % in salmonide fish farms. Since its initial description in Chile in 1989, the disease has also been recorded in salmonids in Norway, Canada, Ireland and Scotland. In addition, Pisciri...

Awarded: NOK 3.7 mill.

Project Period: 2007-2009

Location: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

National resources for genomics, functional genomics and health research in Atlantic salmon and Atlantic cod. WP 3 (tidl del av177030)

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Awarded: NOK 2.4 mill.

Project Period: 2007-2010

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Mouse models for studying oxidative demethylation of DNA and RNA

It was recently discovered that the AlkB protein from E. coli uses a novel mechanism, termed oxidative demethylation, to remove deleterious methyl lesions from DNA and RNA. Eight mammalian AlkB homologues, denoted ABH1 - ABH8 (mABH1-8 in mice), exist, and two of these, ABH2 and ABH3, have been s...

Awarded: NOK 10.0 mill.

Project Period: 2006-2012

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Norsk Eurobarometer

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Awarded: NOK 98,499

Project Period: 2006-2008

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Role of phosphorylation in regulation of redox-mediated events in apoptotic cell death

The blue-green algal toxins: nodularin and microcystin, induce apoptotic cell death in an ultrarapid manner (Fladmark et al., 1999). These toxins inhibit the general protein phosphatases (PP1 and PP2A) thereby resulting in Ca2+/calmodulin-dependent protei n kinase (CaMKII) hyperphosphorylation of...

Awarded: NOK 1.7 mill.

Project Period: 2006-2010

Location: Vestland

FUGE-Funksjonell genomforskn.i Norg

Host-pathogen interactions: In vitro and in vivo exploration of the quorum sensing system of the marine fish pathogen Vibrio salmonicida.

The genus Vibrio is among the most numerous and ubiquitous of marine bacteria and commonly found as etiological agents of diseases in both vertebrates and invertebrates throughout the world. Vibrio salmonicida, a halophilic and psychrophilic (cold adapted ) marine gram-negative bacterium, the eti...

Awarded: NOK 6.3 mill.

Project Period: 2006-2009

Location: Troms - Romsa - Tromssa

FUGE-Funksjonell genomforskn.i Norg

Regulatory mechanisms and interactions of non-protein-coding RNAs

Genome sequencing has shown that the complexity of an organism is not primarily determined by the number of genes, but rather by the diversity of how these genes are regulated and processed. In particular non-protein-coding RNAs (ncRNA) have been shown to be involved in important aspects of gene...

Awarded: NOK 6.3 mill.

Project Period: 2006-2010

Location: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

Development of a Peptide-based Universal Influenza Vaccine

This study aims to develop a safe and effective peptide-based universal influenza vaccine targeting dendritic cells, that stimulates cell mediated immunity to reduce morbidity and mortality associated with influenza virus infection. Such a vaccine can be made in advance of a pandemic and can also...

Awarded: NOK 8.2 mill.

Project Period: 2006-2010

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Genomics as a tool for detecting selection in farm Atlantic salmon and interactions between escaped farm and wild salmon

Norway is of unique importance for the Atlantic salmon, both as the largest producer of farmed salmon and a main reservoir of wild stocks. However, escaped farmed fish make up a significant portion of spawners in the wild, and there is concern that the ge netic constitution of wild stocks is dete...

Awarded: NOK 6.0 mill.

Project Period: 2006-2010

Location: Troms - Romsa - Tromssa

FUGE-Funksjonell genomforskn.i Norg

Immune stimulating responses of biopolymers with particular reference to treatment of chronic wounds

Chronic wounds are a major world health problem; estimated to affect 3% of the population over the age of 65. There is a demand in the wound healing marked for new efficient products. The chronic wound bed represents a very complex system where bacteria a nd their products and degraded proteins c...

Awarded: NOK 4.0 mill.

Project Period: 2006-2009

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Developing the SALBANK resource

The SALBANK population was set up as an experimental cross to detect QTLs and genes. By crossing strains that have been geographically isolated since the glacial period: the relict strain Byglandsbleka and the Norwegian elite population NLA followed by in ter crosses, family sets with an expected...

Awarded: NOK 1.4 mill.

Project Period: 2006-2009

Location: Troms - Romsa - Tromssa

FUGE-Funksjonell genomforskn.i Norg

1st Seeberg Symposium on DNA repair

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Awarded: NOK 99,999

Project Period: 2006-2006

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

SciLab i Elverum august 2006

(Utkast til omtale i program) Forskerspirer kan prøve seg Under De Nordiske Jakt- og Fiskedager som arrangeres på Norsk Skogmuseum 10. ? 13. august 2006 kan barn ?i alle aldre? prøve seg som forskere i lekelabben SciLab. Her kan man lære hvordan arvestoff (DNA) blir isolert og analysert. Bruk av...

Awarded: NOK 39,999

Project Period: 2006-2007

Location: Vestland

FUGE-Funksjonell genomforskn.i Norg

Filmer om moderne bioteknologi

(Vi ønsker å presisere at innholdet i filmene ikke er endelig bestemt. FUGEs representanter i prosjektgruppen vil være med på å forme opplegget i henhold til FUGEs mandat.) Vi ønsker å bidra til informasjon og offentlig debatt med et filmbasert undervis ningsopplegg om bioteknologi og etikk. G...

Awarded: NOK 0.40 mill.

Project Period: 2006-2009

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

CIGENE resource and core project proposals for the GENOFISK call May 8th

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Awarded: NOK 10.0 mill.

Project Period: 2006-2010

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Heart and skeletal muscle inflammation (HSMI) - molecular characterisation of the virus and vaccine development

Heart Skeleton muscle innflammation (HSMI) has been an increasing problem in Norwegian salmon farming since the first occurence in 1999. This project aims at a further characterization of the HSMIV viral genome and viral proteins (WP1) as a basis for prod ucing recombinant virus protein and makin...

Awarded: NOK 3.6 mill.

Project Period: 2006-2009

Location: Trøndelag - Trööndelage