IS-MOBIL-Mobilitetsprogr.f.utl.Ph.D-stu
Assess the role of the mitochondrial-nuclear connection in modulating neuronal autophagy
Backround and R&D challenge:
Friedreichs ataxia (FRDA), the most frequent inherited recessive ataxia, causes nervous system damage and movement problems, it is ascribed to severely defective expression of frataxin, a nuclear-encoded mitochondrial protein . Autophagy is not only the major pathway...