249 projects

Date from new to old

HELSEFORSKNING-Helseforskning

Optimizing Migraine Prevention (OptMig project)

Migraine is a chronic neurological disorder characterized by attacks of pulsating, often unilateral headaches that worsen with physical activity. The condition is often accompanied by sensitivity to light and sound, as well as nausea and/or vomiting, and it worsens with physical activity. Patient...

Awarded: NOK 15.0 mill.

Project Period: 2019-2025

Location: Trøndelag - Trööndelage

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Online psychosocial support for young people distressed by appearance-altering conditions: A randomised control trial (RCT)

Looking different in a society that values appearance can be challenging, especially during adolescence. Many different conditions can affect appearance, such as for example a craniofacial condition such as a syndrome or a cleft lip and palate, skin conditions, or acquired conditions such as a bu...

Awarded: NOK 9.8 mill.

Project Period: 2019-2024

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Maternal hemodynamics in hypertensive disorders of pregnancy- a human and animal model under antihypertensive therapy

Hypertensive disorders of pregnancy (HDP) have been the leading cause of maternal and neonatal morbidity and mortality worldwide over the last decades. Recently, the common belief of preeclampsia (PE), defined as an increased blood pressure and organ dysfunction such as protein loss after 20 week...

Awarded: NOK 2.7 mill.

Project Period: 2019-2024

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

When and how to apply ultra-low dose Cone Beam Computed Tomography on children with impacted canines

Impaction of the permanent maxillary canine is a condition, in which the tooth is embedded in the jawbone, and its eruption is prevented. Apart from wisdom teeth, canines are the teeth that are most often impacted, with an incidence of 2-3% in Scandinavian children and adolescents. If the canines...

Awarded: NOK 0.30 mill.

Project Period: 2019-2020

Location: Vestland

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Electromechanical Presages of Sudden Cardiac Death in the Young: integrating imaging, modelling and genetics for patient stratification

In the young (<40 years), sudden cardiac death is often the first manifestation of a genetic cardiac disease causing lethal arrhythmias. Both male gender and physical exercise are known risk factors for lethal arrhythmias in this vulnerable population. Current understanding of how gender-related ...

Awarded: NOK 3.0 mill.

Project Period: 2019-2024

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Strengthening of H2020-funded project "OligoGpivotalCF"

AlgiPharma is the coordinator of a Horizon 2020 supported project ("OligoGpivotalCF") with main objective to bring our drug candidate "OligoG" to the market as a drug for Cystic Fibrosis (CF) by conducting a pivotal clinical trial in humans. This project will strengthen and support "OligoGpivotal...

Awarded: NOK 1.00 mill.

Project Period: 2019-2022

Location: Akershus

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Trygge barn i tannbehandling - kunnskapsbygging, forebygging og behandling av barn og ungdom med sprøytefobi og tannbehandlingsangst

The background for the pre-project "Safe children in dental care: knowledge building, prevention and treatment of needle phobia and dental treatment anxiety" is that a large proportion of the population experiences a high degree of stress, fear, discomfort and avoidance related to dental care, an...

Awarded: NOK 0.30 mill.

Project Period: 2019-2020

Location: Trøndelag - Trööndelage

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Orofacial pain- characterization and comparison with larger patient groups are needed to improve oral and general health

Orofacial pain (OFP) is prevalent in the general population-around 17-26%, of which 7-11% is chronic. The etiology and risk factors for development of OFP are current knowledge gaps. The interface between the dental- and medical health services is broad and improved collaboration is needed. The p...

Awarded: NOK 0.30 mill.

Project Period: 2019-2020

Location: Vestland

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Konferanse 2019: Demensomsorg. Likheter og ulikheter i bruk av kommunale helse- og omsorgstjenester i Nord-Norge

Konferansen vil formidle kunnskap om ulikhet i tildeling og bruk av helsetjenester, noe som kan føre til ulikhet i helse, og er spesielt innrettet mot underrepresenterte grupper. Kunnskap om tildeling av, og barrierer for å motta tjenester, hvilke mekanismer som er i spill, vil i neste omgang kun...

Awarded: NOK 0.13 mill.

Project Period: 2019-2022

Location: Troms - Romsa - Tromssa

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Setting up of immunoassay for salivary carbonic anhydrase isoenzyme 6 (CA6), a putative biomarker for dental caries prediction

Dental caries is a major global health problem affecting 60-90% of school children and nearly all adults. Estimated 2 million Norwegians have untreated caries. Individual caries increment is associated with saliva quality, especially on the amount of salivary carbonic anhydrase isoenzyme 6 (CA6)....

Awarded: NOK 0.30 mill.

Project Period: 2019-2020

Location: Troms - Romsa - Tromssa

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Mental Health and Obesity (the MHOBY study).

Background Patients with obesity and co-existing mental disorders are typically offered traditional weight loss approaches and/or bariatric surgery or receive no treatment at all due to their mental disorder. By ignoring possible comorbid mental disorders in their diagnosis (assessment) and tr...

Awarded: NOK 0.30 mill.

Project Period: 2019-2020

Location: Trøndelag - Trööndelage

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Healthy oral aging, an interdisciplinary approach

Oral health is essential to general health and quality of life. However, due to misconceptions, educational traditions, separate institutions, incompatible patient information systems, and shortage of financing, a worldwide gap exists between medicine and dentistry. This results in lack of focus ...

Awarded: NOK 0.30 mill.

Project Period: 2019-2020

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Klinisk Rettsodontologisk undersøkelse av barn utsatt for vold og/eller seksuelle overgrep (KRu-barn).

Every day, children and adolescents are subject to violence and / or sexual abuse. Statistics show that 21% of children in Norway have experienced physical violence during their childhood and that more than 1 in 5 women and 1 in 10 men have been victims of sexual abuse. The health consequences of...

Awarded: NOK 0.16 mill.

Project Period: 2019-2020

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Helsetjenesteforskningskonferansen 2019

Helsetjenesteforskningskonferansen 2019 er berammet til 12.-13.3. 2019, og vil være i Trondheim. Dette vil bli den tredje gangen at denne konferansen arrangeres. Helsetjenesteforskningsmiljøet ved SINTEF, avdeling Helse er stedlig hovedarrangør. Den første Helsetjenesteforskningskonferansen (20...

Awarded: NOK 0.21 mill.

Project Period: 2019-2019

Location: Trøndelag - Trööndelage

HELSEFORSKNING-Helseforskning

Cost-effectiveness of a multidisciplinary intervention and subsequent use of health care resources in patients on waiting list for TKA

Studien tester effekten av fysisk trening kombinert med mental trening for pasienter med smertefull kneartrose som er på venteliste for operasjon med kneprotese. Fysioterapeutene har en sentral rolle i studien som vil foregå ved Lovisenberg Diakonale Sykehus i Oslo, ved Martina Hansens Hospital ...

Awarded: NOK 10.0 mill.

Project Period: 2019-2028

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Residual adrenocortical function in patients with autoimmune Addison`s disease

rimary adrenocortical insufficiency (Addison's disease) is a rare, but potentially lethal endocrine disorder. In spite best practice treatment, many patients experience reduced health and quality of life. Addison's disease is usually caused by autoimmune destruction of the adrenal cortex, and it ...

Awarded: NOK 9.6 mill.

Project Period: 2019-2023

Location: Vestland

HELSEFORSKNING-Helseforskning

The Child-In-Context-Intervention (CICI): A randomized controlled trial addressing chronic symptoms of Pediatric Acquired Brain Injury

Brain injury due to e.g. accidents, brain tumors or stroke is known as acquired brain injury (ABI). Children with ABI often struggle with complex impairments, including cognitive (such as memory and attention), social, emotional and behavioral challenges. We have knowledge about how to help child...

Awarded: NOK 15.6 mill.

Project Period: 2019-2026

Location: Akershus

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Bidrag til utlysning om barnekreft

...

Awarded: NOK 8.0 mill.

Project Period: 2018-2019

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Life After STroke. A Norwegian long-term follow-up project (LAST-long)

We have solid knowledge about the best treatment in the acute and subacute phases for patients affected by stroke. Unfortunately, we cannot say the same about long-term follow-up. The main objective of the LAST-long study (Life After Stroke. A Norwegian long-term project) was to meet this challen...

Awarded: NOK 14.7 mill.

Project Period: 2018-2026

Location: Trøndelag - Trööndelage

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Innovating the clinical pathway for home-dwelling people with dementia and their families. A mixed-method randomized controlled trial

The provision of economically viable and proper care for the growing group of home-dwelling persons with dementia (PWD) is one of the most pressing issues in our society. While a cure for dementia is not yet available, professionals and policy-makers highly prioritize the support of caregivers wh...

Awarded: NOK 16.4 mill.

Project Period: 2018-2023

Location: Vestland

HELSEFORSKNING-Helseforskning

Individualized blood pressure treatment: A multidisciplinary approach to uncontrolled hypertension in order to reduce morbidity and mortalit

Hypertension is assumed to affect approximately 40% of the adult population worldwide, making it the most important modifiable risk factor for morbidity and mortality. In addition to lifestyle changes, long-term use of antihypertensive medication is essential to prevent kidney disease, cerebrovas...

Awarded: NOK 15.2 mill.

Project Period: 2018-2027

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Physical Activity and Fitness among Childhood Cancer Survivors

The PACCS project aims to develop evidence-based physical activity (PA) recommendations to improve the long-term care of childhood cancer survivors (CCSs). There are currently more than 5000 CCSs in Norway, and the majority is at risk of developing treatment-induced late effects (health problems...

Awarded: NOK 15.8 mill.

Project Period: 2018-2023

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Improving treatment for women with endometrial cancer

Endometriale cancer is one of the most common forms of cancer affecting women. The incidence is increasing, partly due to increased life expectancy, but endometrial cancer is also strongly associated with obesity. Although the prognosis for most patients is good, there are few treatment options i...

Awarded: NOK 12.3 mill.

Project Period: 2018-2023

Location: Vestland

HELSEFORSKNING-Helseforskning

Mapping and interrogating top-down control of the memory engram of the posttraumatic stress disorder.

The onset of post-traumatic stress disorder (PTSD) is triggered by a life threatening experience, which leaves a lasting trace of fear memory. Individuals with PTSD are unable to distinguish the similarities between different contexts; memories become largely generalized, so that a similar contex...

Awarded: NOK 1.9 mill.

Project Period: 2018-2025

Location: Vestland

HELSEFORSKNING-Helseforskning

Type 2 DIAbetes in South Asian immigrants. Pathophysiology, Perceptions, Prevention and Treatment - The DIASA research programme

DIASA1: The study revealed a high prevalence of prediabetes in women 16 months after gestational diabetes, particularly among women of South Asian descent. A qualitative sub-study identified significant areas for improvement that can be implemented in the follow-up of women with gestational diabe...

Awarded: NOK 18.3 mill.

Project Period: 2018-2026

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Stem Cell Therapy for Bone Regeneration in Maxillofacial and Orthopaedic Surgery

Bone defects and incurable bone diseases remain major challenges in modern medicine. As a result, advanced therapies, particularly stem cell therapy and tissue-engineered products, are increasingly being explored as promising solutions in regenerative medicine. In both Norway and Europe, millions...

Awarded: NOK 15.1 mill.

Project Period: 2018-2025

Location: Vestland

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Exploitation of extracellular vesicles for precision diagnostics of prostate cancer.

Prostate cancer is the most common male cancer in Europe, where it affects approximately 400,000 men annually. The development of sensitive non-invasive biomarkers for differentiating between indolent prostate cancer and aggressive prostate cancer requiring aggressive treatment represents a great...

Awarded: NOK 2.7 mill.

Project Period: 2018-2022

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Microbiota-based SCReening of Anal Cancer in HIV-infected individuals (SCRAtCH)

The risk of anal cancer is markedly increased in HIV-infected subjects, in part due to high prevalence of human papilloma virus (HPV) among men who have sex with men (MSM). The current screening strategy is based on detection of early stages of cancer or cancer precursors using anal cytology. Wh...

Awarded: NOK 0.59 mill.

Project Period: 2018-2022

Location: Oslo - Oslove

HELSEFORSKNING-Helseforskning

Understanding psychosis, cognitive impairment and motor symptoms induced by NMDA receptor dysfunction: mechanisms to prevention and therapy

Schizophrenia is one of the most severe psychiatric disorders with onset of symptoms during early adulthood, followed in many cases by lifelong chronic illness that generates a high need for healthcare follow up, social difficulties and reduced quality of life. The causes of schizophrenia remain ...

Awarded: NOK 2.5 mill.

Project Period: 2018-2025

Location: Oslo - Oslove

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

SNAREopathies: Mechanisms of neuropsychiatric genetic diseases of the SNARE complex: towards therapeutic intervention

Incorrect signal transmission between neurons often occurs in association with major brain diseases, and can lead to epileptic seizures at any stage in life. Proteins from the SNARE complex play an important role in signal transmission. They regulate the release of signalling molecules from one n...

Awarded: NOK 2.3 mill.

Project Period: 2018-2022

Location: Oslo - Oslove

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