9,425 projects

SIP-NHD-Strategiske instituttprogram finansiert av NHD

Making Rich Media Accessible for Generations

The main theme of MARIAGE is the ability to publish and access rich media material over a long period of time. The right-most column illustrates that we want to improve commercial services of different types at different level. Three problem areas that need to be solved for making rich media ac...

Awarded: NOK 6.0 mill.

Project Period: 2007-2009

Location: Oslo

SIP-NHD-Strategiske instituttprogram finansiert av NHD

A systems biology approach to the understanding of antibiotic production in the model organism Streptomyces coelicolor

Systems Biology aims at understanding and predicting the properties of a biological system under targeted perturbations (e.g. genetic changes or changes in the external environment) with the use of integrated data analyses and mathematical modelling. It requires a multidisciplinary approach incl...

Awarded: NOK 5.7 mill.

Project Period: 2007-2010

Location: Trøndelag - Trööndelage

SIP-NHD-Strategiske instituttprogram finansiert av NHD

Evidence-Based Software Engineering

Software development is critical for the modern society. Still, many software projects are completed late and have substantial cost overruns. Recently, agile software development has emerged as a radical new way of organizing the development process, stro ngly emphasizing change tolerance, evolut...

Awarded: NOK 9.0 mill.

Project Period: 2007-2009

Location: Trøndelag - Trööndelage

TU-Tungt utstyr

Isothermal Titration Calorimeter

An important aspect within biological chemistry research projects at the University of Stavanger (UiS) is to identify and characterize protein-protein as well as protein-nucleic acid interactions. In these projects, including signal transduction in plant nitrogen metabolism (Prof. C. Lillo), ch...

Awarded: NOK 1.3 mill.

Project Period: 2007-2009

Location: Rogaland

SIP-NHD-Strategiske instituttprogram finansiert av NHD

Microtechnological research platform

The project utilizes the production facilities at SINTEF MiNaLab as a tool for University research. This production line is fully ISO sertified and offers state-of-the-art equipment for silicon based MEMS production. The project funds both production of d evices and training of students. The mai...

Awarded: NOK 21.0 mill.

Project Period: 2007-2010

Location: Trøndelag - Trööndelage

SIPOPETR-SIP-OED Petroleumssektoren

Multimodal flow assurance metering station (MuFAMES).

Subsea processing and transportation of multiphase fluids over long distances is becoming a viable solution for several subsea fields. Flow assurance is becoming an increasing challenge as depth and step out length are increasing. The processes conditions with low temperatures have the potential...

Awarded: NOK 12.0 mill.

Project Period: 2007-2010

Location: Vestland

FRIBIO-Biologi og biomedisin

Quantification and Characterization of Microbial Communities in Air.

There is a serious lack of knowledge concerning the presence, activity and dispersal of airborne microorganisms. Most studies describing the prevalence of airborne microorganisms have only applied traditional microbiological methods and evaluated the occu rrence of culturable bacteria, which is k...

Awarded: NOK 2.6 mill.

Project Period: 2007-2009

Location: Vestland

FRIBIO-Biologi og biomedisin

Mechanism of cargo selectivity in axonal transport Isolation and characterization of kinesin light chain associated vesicles

The aim of this project is to gain knowledge about how the motor protein kinesin-I interacts with its vesicle cargo, and what the nature is of the vesicles that are transported by kinesin-I through neurons. The role of neuronal transport in neurodegenerat ive diseases such as Alzheimer's disease,...

Awarded: NOK 2.7 mill.

Project Period: 2007-2011

Location: Oslo

FRIBIO-Biologi og biomedisin

Dynamics of synaptic transmission in the rod pathway of the retina

A considerable challenge in neuroscientific research is to explain processes at the systems level in terms of mechanisms at cellular and molecular levels. The retina serves as an ideal model system amenable to experimental approaches that directly aim to bridge this gap. With respect to the senso...

Awarded: NOK 3.0 mill.

Project Period: 2007-2010

Location: Vestland

FRIBIO-Biologi og biomedisin

Vaccine development for HIV and influenza

Aim: Based on the vaccibody principle developed by us, we wish to generate novel vaccines for important infectious diseases such as HIV and influenza. Background: Vaccination has had an enormous impact on health and longevity of humans world-wide. However , for some important diseases such as HIV...

Awarded: NOK 3.1 mill.

Project Period: 2007-2010

Location: Oslo

FRITEK-Teknologi

High-level Formal Modeling and Analysis of Real-Time and Hybrid Systems

The functionality of many modern advanced computer systems -- such as, e.g., wireless sensor networks, the Internet and other kinds of networks, and control systems -- is crucially dependent on the amount of time that passes during/between events. Furthe rmore, such advanced and often critical s...

Awarded: NOK 4.6 mill.

Project Period: 2007-2011

Location: Oslo

FRIMED-Klinisk medisin og folkehelse

The Tromsø Pain Study: Causes and consequences of individual differences in pain sensitivity

Human pain sensitivity is subject to very large inter-individual variation. It is known that pain sensitivity is heritable, but the genes involved are largely unknown. Hypersensitivity to pain may be an important risk factor in the development, maintenanc e and consequences of chronic pain. Reduc...

Awarded: NOK 3.7 mill.

Project Period: 2007-2010

Location: Oslo

FRIMED-Klinisk medisin og folkehelse

Tissue engineering in bone defects: Development of porous copolymer scaffolds stimulating stem cell growth and bone regeneration

For the repair of bone defects, tissue engineering would be to combine cells capable of osteogenic activity with an appropriate scaffold. Mesenchymal stem cells are multipotential cells that are capable of differentiating into different type of cells dep ending on culture condition. The selectio...

Awarded: NOK 3.1 mill.

Project Period: 2007-2011

Location: Vestland

NATURNAER-Natur og næring

Mapping and identification of the mutation causing Epiphyseal Dysplasia in Norwegian Hunting dogs, postdoc

Hunting is a widespread activity of importance for individual recreation and has a great value for local tourist industry in the country side. Most hunting is dependent on a healthy population of hunting dogs. Norway has three national hunters (breeds) wh ich are used for the major part of huntin...

Awarded: NOK 1.9 mill.

Project Period: 2007-2011

Location: Oslo

MATPROG-Matprogrammet: Norsk mat fra sjø og land

A Study of Influenza Viruses in Their Natural Reservoir in Wild Birds in Norway

The major goal of this project is to better understand the dynamics of influenza A virus infections in wild birds in Norway. At the National Veterinary Institute, in the context of the surveillance for highly pathogenic avian influenza virus H5N1, a large collection of samples is being gathered ...

Awarded: NOK 4.3 mill.

Project Period: 2007-2011

Location: Viken

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Attractive host plant volatiles and genetic regulation of the olfactory response in the control of apple fruit moth, Argyresthia conjugella

The apple fruit moth Argyresthia conjugella is regarded as the most important insect pest on apples in Fennoscandia. Until 2005 the organophosphorous compound azinphos-methyl (Gusathion) has been used in apple fruit moth control. The compound is now dereg istrated due to environmental concerns an...

Awarded: NOK 6.8 mill.

Project Period: 2007-2011

Location: Viken

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Reduction/elimination of spore forming bacteria in lightly heat treated foods

The project seeks to identify processes which are able to strongly reduce spore forming bacteria in lightly heat treated (<98 ºC) foods. To solve this task, three research groups with different, complementary competence will cooperate. The project require s characterisation of potentially pathoge...

Awarded: NOK 5.1 mill.

Project Period: 2007-2010

Location: Oslo

BIONÆR-Bionæringsprogram

Safe grains: Mycotoxin prevention through resistant wheat and oats

In 2004 there were alarming levels of mycotoxins like DON and T-2/HT-2in Norwegian wheat and oats. In 2005 the latter levels in oats were prohibitive for e.g. horsefeed. The present proposal builds on a decade of Norwegian cereal breeding and research to introduce/identify resistance against the ...

Awarded: NOK 7.3 mill.

Project Period: 2007-2013

Location: Viken

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Rapid DNA-based prediction of mycotoxin levels in food and feed

The major mycotoxin producers in foods in Norway and Europe are members of the genera Aspergillus, Fusarium and Penicillium. Two major classes of mycotoxins produced by Fusarium spp. are trichothecenes and fumonisins. The biosynthetic pathways involve gen es organised in (Tri- and Fum-) gene clus...

Awarded: NOK 2.6 mill.

Project Period: 2007-2011

Location: Viken

BIONÆR-Bionæringsprogram

Technology and methods using high-density microarrays for detection of unknown genetic modifications in plants, fungi and bacteria

To ensure the safety of genetically modified organisms (GMOs) they are subjected to risk assessment prior to release into the environment and use in e.g. food production. Such known GMOs are considered to be as safe as conventional varieties. GMOs for whi ch publicly available descriptions are un...

Awarded: NOK 3.1 mill.

Project Period: 2007-2012

Location: Viken

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Automatic weed assessment for precision spraying in cereals

The load of herbicides on Norwegian cereals fields is unnecessarily high. The spraying represents an unnecessary cost for farmers, in Norway estimated to about 20 millions NOK yearly, and lots of herbicides superfluously spread to the environment. The mos t important reason for this excessive her...

Awarded: NOK 4.7 mill.

Project Period: 2007-2010

Location: Viken

BIONÆR-Bionæringsprogram

Preclinical diagnosis of prion disease

Transmissible spongiform encephalopathies (TSEs) are a threat to food safety and to human and animal health. Diagnosis of these diseases and early detection of the infective agent is vital for future spread and prevention of disease. The identification of candidate molecules as biomarkers of pre...

Awarded: NOK 7.0 mill.

Project Period: 2007-2012

Location: Oslo

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Stability and mobility of Shiga toxin-encoding bacteriophages in clinical and environmental strains of Escherichia coli O103

E. coli O103 belongs to a subset of serotypes of Shiga toxin-producing Escherichia coli (STEC) associated with severe human illnesses. Shiga toxin (Stx) production is essential but not sufficient for virulence in pathogenic STEC as factors involved in att achment, haemolysis and iron scavenging a...

Awarded: NOK 3.2 mill.

Project Period: 2007-2010

Location: Oslo

FRIBIO-Biologi og biomedisin

Elucidation of downstream signaling events of cAMP using new tools distinguishing the roles of EPAC and PKA

The present project will receive Epac and PKA modulating cAMP analogs. I. We will test selected new analogs in a newly developed and unique assay for binding to PKA holoenzyme II. The best activators (current or novel) will be used, separately and jointl y, to define effect of Epac and PKA activ...

Awarded: NOK 3.1 mill.

Project Period: 2007-2011

Location: Vestland

FRIBIO-Biologi og biomedisin

The role of excitatory amino acid in Parkinson's disease

Parkinson's disease is characterised by death of dopamine containing neurons in the substantia nigra. Long term levo-dopa treatment has severe side effects and is potentially toxic for neurons. The need for alternative treatments in Parkinson's disease is urgent. To accomplish this, further rese...

Awarded: NOK 2.3 mill.

Project Period: 2007-2010

Location: Oslo

FRIBIO-Biologi og biomedisin

The role of normal neighbouring keratinocytes and fibroblasts on clonal expansion of oral cancer (stem) cells

Recent studies, including ours, have shown that the invasive behaviour of cancer cells is not solely due to mechanisms intrinsic to the individual tumour cell. Genetic changes of individual cells in a specific tissue are not sufficient for invasive cancer to develop. Rather, there is a vivid cro...

Awarded: NOK 1.1 mill.

Project Period: 2007-2009

Location: Vestland

FRIBIO-Biologi og biomedisin

Electrical signaling in thin dendrites and axons in the cortex

A major challenge in neuroscience is to understand the mechanisms of neuronal computation, much of which is carried out by electrical signals generated by ion channels in the cell membrane. Within the last decade, advances in patch-clamp and imaging techn iques have extended our knowledge of such...

Awarded: NOK 2.5 mill.

Project Period: 2007-2011

Location: Oslo

EVITA-eVitenskap

Nasjonal møteserie i eVitenskap

Programstyret for eVita ønsker å etablere en nasjonal møteplass for eVitenskap som en utvidelse av konseptet med vinterskoler som har vært arrangert i regi av BeMatA programmet. Det utvidede konseptet består av en ukes vinterskole og et to-dagers forskerm øtet, arrangert ved et norsk vintersports...

Awarded: NOK 0.95 mill.

Project Period: 2007-2010

Location: Oslo

HAVBRUKS-Havbruk - en næring i vekst

Heart and skeletal muscle inflammation (HSMI) in Atlantic salmon: diagnosis, pathogenesis and epidemiology

Heart and skeletal muscle inflammation (HSMI) is a transmissible disease of viral aetiology affecting farmed Atlantic salmon. The disease appears to be spreading rapidly into new areas, and it is important to limit further spread. HSMI is characterized by severe inflammation in heart and red ske...

Awarded: NOK 4.2 mill.

Project Period: 2007-2011

Location: Viken

HAVBRUKS-Havbruk - en næring i vekst

ONTOGENY OF LIPID DIGESTION AND EFFECTS OF FEEDING PRE-DIGESTED LIPIDS TO ATLANTIC COD (GADUS MORHUA) LARVAE

Lipids provide cod larvae with energy and essential fatty acids, the latter being structural components of biological membranes and precursors for the eicosanoids; signalling molecules which participate in regulation of a range of biological processes. Un til now, research on dietary lipids for m...

Awarded: NOK 2.9 mill.

Project Period: 2007-2009

Location: Vestland