149 projects

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

EUROCORES: Genetic targets of epileptogenesis and pharmacoresistance in brain glial cells - a translational research project on the genetic

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Awarded: NOK 3.0 mill.

Project Period: 2011-2015

Location: Oslo

FRIMED-Klinisk medisin og folkehelse

ESC Working Group on Cardiac Cellular Electrophysiology

The ESC Working Group on Cardiac Cellular Electrophysiology is an annual international meeting, bringing prominent scientists and group leaders within the field together with young scientists. Host function is circulating among the European partners tha t have contributed importantly to the wor...

Awarded: NOK 0.20 mill.

Project Period: 2011-2011

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Structural and functional connectivity in the aging brain: cognitive consequences and genetic modifiers

The main aim of the project is to characterize changes in the structural and functional makeup of the brain which are associated with normal age-related variation and various mental and neurological disorders. Next, we seek to identify cognitive and clinical associations with these brain network ...

Awarded: NOK 4.9 mill.

Project Period: 2011-2015

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Mechanisms for vascular disease in women - Inflammation in pre-eclampsia and atherosclerosis

Women with preeclampsia have doubled risk for developing cardiovascular disease later in life. Pregnancy represents a metabolic stress test and abnormal changes in preeclampsia may represent an early sign of cardiovascular disease in some women. Both diseases are characterized as inflammatory and...

Awarded: NOK 5.1 mill.

Project Period: 2011-2017

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Pre- and postnatal environmental and genetic factors in relation to brain development in the Norwegian Mother and Child Cohort Study

In year 1, we developed protocols for testing and examinations, planned strategies for recruitment in collaboration with Norwegian Institute of Public Health and the Medical Birth Registry of Norway, and procedures for recruitment, testing and scanning were coordinated and standardized between co...

Awarded: NOK 10.9 mill.

Project Period: 2011-2015

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Inflammatory markers, kynurenines, and B-vitamins in relation to chronic disease and mortality in a population based prospective study

Inflammation plays a key role in the onset of many chronic diseases. Although extensive research has been carried out in the past decades to unravel the role of B-vitamins in cardiovascular disease (CVD) and cancer, exact mechanisms behind observed inverse associations of B-vitamins with CVD and ...

Awarded: NOK 5.7 mill.

Project Period: 2011-2015

Location: Vestland

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Konferansen for International Society for Clinical Biostatistics (ISCB) i 2012

International Society for Clinical Biostatistics (ISCB) ble startet i 1978 og avholder internasjonale årlige konferanser. Se foreningens internettsider: http://www.iscb.info/. Konferansen for 2012 vil avholdes i Bergen. Konferansene i 2010 og 2011 avholde s i Montpellier, Frankrike (http://www.is...

Awarded: NOK 0.20 mill.

Project Period: 2011-2012

Location: Vestland

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Biomechanical characteristics of patients with hip osteoarthritis with mild to moderate pain: A prospective, randomized clinical trial

This project funding proposal concerns a personal postdoctoral fellowship within the area of clinical research. The project will investigate the effect of exercise therapy and patient education compared to patient education alone on lower extremity biomec hanics during gait, sit-to-stand, and one...

Awarded: NOK 2.4 mill.

Project Period: 2011-2014

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

The identification of new genetic causes of Parkinson's disease

Parkinson disease (PD) is a common neurological disorder affecting about 1% of the population aged 60 or older. The disorder is causing high costs to society and reduced quality of life in patients and caregivers. Like many other neurological illnesses, P D is chronic, progressive and only sympto...

Awarded: NOK 7.0 mill.

Project Period: 2011-2016

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Molecular alterations for targeting therapy in metastatic gynecologic cancer

Endometrial cancer is the most common and ovarian cancer the most lethal pelvic gynaecologic malignancies. Improved treatment for metastatic disease and reliable predictors for response to therapeutics are needed. Serous papillary endometrial- and ovarian carcinomas share an aggressive course of...

Awarded: NOK 9.2 mill.

Project Period: 2011-2016

Location: Vestland

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Effectiveness of colorectal cancer screening on colorectal cancer incidence and mortality

Objective 1: The analyses of 10 year follow-up of the NORCCAP trial is now being finalised. Hopefully, the paper(s) will be published late 2013 early 2014. Objective 2: One of the main collaborators in this project, Ewa Kraszewska published her doctor al thesis in Warsaw, Polen this year (Warto...

Awarded: NOK 2.7 mill.

Project Period: 2011-2014

Location: Telemark

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Bio-Epidemiology of Fitness and Cardiovascular disease From Society to Molecules and back again

We have since the start-up of the project had the following main achievements: 1) we have established the worlds largest reference material on fitness in a healthy population aged 20-90 years, 2) we have demonstrated that it is possible to determine fitness using a non-exercise model that now pro...

Awarded: NOK 9.4 mill.

Project Period: 2011-2015

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Viral infections during early infancy, pregnancy and type 1 diabetes risk

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Awarded: NOK 2.6 mill.

Project Period: 2011-2014

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

A longitudinal population study of infant vulnerability and plasticity from pregnancy to age 18 months

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Awarded: NOK 12.4 mill.

Project Period: 2010-2017

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

From clinical to molecular characterization of multiple sclerosis

Objective 1: Genotype-phenotype analyses of Nordic genome wide association (GWA) screen data We have analyzed GWAS data from Scandinavian MS patients to search for genetic differences in MS based on Oligoclonal Band (OCB) status. GWAS data of 1406 OCB positive and 168 OCB negative MS patients wa...

Awarded: NOK 7.8 mill.

Project Period: 2010-2016

Location: Oslo

FRIMED-Klinisk medisin og folkehelse

International Confernce on discovery based translational research

Following very successful meetings in recent years, the European Association for Cancer Research (EACR) will be staging its biennial conference EACR 21 in Oslo to discuss the latest developments in cancer research and science. The conference will be broad and balanced, and will include Gene Expr...

Awarded: NOK 0.25 mill.

Project Period: 2010-2011

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

The association between dietary intake and biomarkers for nutrients and disease

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Awarded: NOK 4.1 mill.

Project Period: 2010-2016

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Clinical features of autism spectrum disorders

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Awarded: NOK 4.0 mill.

Project Period: 2010-2015

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

A whole-genome approach to monogenic and type 1 diabetes: Copy-number variation and exome screening

Diabetes is an epidemically increasing, common disease with high morbidity. Recently, there has been a break-through in the identification of diabetes risk genes. Although the genome-wide association studies in type 2 diabetes have been successful in iden tifying common gene variants associated w...

Awarded: NOK 9.7 mill.

Project Period: 2010-2014

Location: Vestland

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Enhanced Minimally Invasive Therapy,- e-MIT

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Awarded: NOK 13.0 mill.

Project Period: 2010-2014

Location: Trøndelag - Trööndelage

FRIMED-Klinisk medisin og folkehelse

Society for Medical Innovation and Technology, Academic Conference 2010, Trondheim, Norway

Society for Medical Innovation and Technology, SMIT (http://www.smit.de/), er en organisasjon som hvert år arrangerer en vitenskapelig tverrfaglig internasjonal konferanse innen temaet medical innovation and technology. Den vitenskapelige konferansens ans var og hovedarrangør er den årlige konfer...

Awarded: NOK 0.25 mill.

Project Period: 2010-2010

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Exercise training as a treatment strategy for improved cardiac metabolism in patients with heart failure and with a transplanted heart

The search for an adequate treatment for heart failure is a major challenge, and even though the medical treatment has been improved substantially in recent years, the mortality rate remains high. During the last decades physical activity has been recogni zed as an important part in the rehabilit...

Awarded: NOK 2.5 mill.

Project Period: 2010-2014

Location: Trøndelag - Trööndelage

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

The Nordic-European Initiative on Colorectal Cancer (NordICC)

Colorectal cancer (CRC) is a major burden in western countries. The disease develops from precursor lesions. Colonoscopy can detect and remove CRC precursor lesions and may thus be effective for CRC prevention. According to European Union guidelines, evid ence from randomised trials to reduce inc...

Awarded: NOK 13.8 mill.

Project Period: 2010-2015

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Investigating social inequalities & determinants of weight development in youth: Applying longitudinal, environmental and experimental data

The researcher project "Investigating social inequalities & determinants of weight development in youth: Applying longitudinal, environmental and experimental data." used data from the Norwegian Longitudinal Health Behavior (NLHB) study, a European cross-sectional survey from the EU-project ENERG...

Awarded: NOK 5.7 mill.

Project Period: 2010-2015

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Fear of childbirth: causes and consequences

The Western world has an epidemic of self-perceived fear of childbirth. Between 5 and 10% of all pregnant women in the Oslo area are being treated for fear of childbirth. Steadily increasing numbers of pregnant women are requesting caesarean sections due to fear of giving birth. However, caesare...

Awarded: NOK 6.6 mill.

Project Period: 2009-2014

Location: Akershus

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Evaluation of functional Magnetic Resonance in the Diagnosis of Brain Tumors for Assessment of Clinical Efficacy (EMBRACE)

In patients suggestive of intra-cranial brain tumors, Magnetic Resonance (MR) is the imaging modality of choice for tumor characterization prior to, during and after surgical intervention. At Rikshospitalet (Oslo, Norway), a multi-disciplinary project has been established with the aim of develop...

Awarded: NOK 7.1 mill.

Project Period: 2009-2013

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

New analytic methods in epidemiology

The theme of the project is causal inference: How to make inferences about causation from statistical data? We are dealing with comparison of the effects of different treatment strategies used in patients with a specific disorder. This is a key issue in assuring the quality of care provided by th...

Awarded: NOK 4.7 mill.

Project Period: 2009-2015

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Hip fractures: Predictors, incidence and survival. NOREPOS: The Norwegian Epidemiological Osteoporosis Studies

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Awarded: NOK 9.2 mill.

Project Period: 2009-2015

Location: Vestland

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Causes of autism spectrum disorders. Epidemiologic studies based on MoBa, the ABC Study and the Autism Database.

Autism spectrum disorders (ASDs) have received considerable public attention in recent years,because of large increases in the prevalence of diagnosed cases in most developed countries,and because of speculations that autism may be caused by vaccines or other environmental exposures. However, kno...

Awarded: NOK 4.0 mill.

Project Period: 2009-2016

Location: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Changes over time in cancer survival and mortality in an ageing Norwegian population and the significance of sociodemographic conditions

The substantial increase in the number of very old persons in Norway over the last decades has had a marked impact on the burden of cancer in our society. This project aims to generate knowledge on changes over time in cancer survival and mortality among the very old, here defined as persons 75 ...

Awarded: NOK 3.1 mill.

Project Period: 2009-2012

Location: Oslo