Slovakia belongs to countries with the highest incidence of colorectal and pancreatic cancer in Europe. Therefore, the main goal of the VISION proposal is to strengthen the scientific excellence and innovative capacity of Biomedicinske centrum Slovenskej akademie vied (BMC SAV), in early detection of gastrointestinal cancer (GI). Creation of a strategic partnership between the coordinator from widening county, BMC SAV and four internationally-recognized institutions, Fraunhofer-Gesellschaft zur Foerderung der Angewandten Forschung e.V. (FhG), Ramón y Cajal University Hospital Health Research Institute represented by Servicio Madrileno de Salud, (SERMAS), Ethniko Kai Kapodistriako Panepistimio Athinon (NKUA), and Norsk Institutt for Luftforskning Stiftelse (NILU) will enhance the credibility and recognition of BMC SAV in European research area. Transfer of knowledge and research ideas, sharing of know-how, expertise and best practices, together with the implementation of cutting edge-technologies, will contribute to the enhancement of high-quality translational cancer research at BMC SAV, particularly GI cancer. Collaboration and networking between VISION partners will accelerate the personal and professional development of early stage researchers and medical doctors, impact the rate of success in internationally competitive research funding and high-quality peer-reviewed publications. Involvement of VISION partners in mentoring and co-supervision of PhD will increase the quality of education at universities, mainly medical and natural science faculties. Moreover, regional and outreach activities supported by VISION will lead to enhanced public awareness of cancer and the importance of prevention.