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HAVBRUKS-Havbruk - en næring i vekst

Effects of environmental and nutritional stress on gene regulation in the Atlantic cod Gadus morhua.

Awarded: NOK 2.7 mill.

The main goal of this project is to develop a microarray platform for gene regulation studies in the Atlantic cod. Stress genes in cod exposed to waterborne pollutants and dietary undesirables and supplements, will be sequenced as expressed sequence tags (ESTs), and a cDNA microarray will be constructed and tested out. Focus will be put on the parts of the transcriptome that are involved in the cellular stress response and other regular stress genes, in addition to a number of housekeeping and control gen es. In this project we apply for a PhD grant, running for three years. The PhD student will work in close contact with the ongoing project “Stress genes in the Atlantic Cod Gadus morhua: EST sequencing and microarray production” (NFR project no.: 159197/I 20). This project operates as collaboration between several researches groups that work on various aspects of stress in fish. Knowledge gained by this project will be of high importance for the establishment of a successful cod aquaculture industry, provi ding biomarker tools in assessing normal status and early signs of adverse fish health, and help pave the way for proteomics. It will also establish the Atlantic cod as the central biomonitoring fish species in marine ecosystems in Norwegian waters, and s trengthen marine molecular biology in Norway.

Funding scheme:

HAVBRUKS-Havbruk - en næring i vekst