Risk factors and pregnancy outcomes of hyperemesis gravidarum (HG)

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Hyperemesis Gravidarum i(HG) s a potentially lethal disorder of early pregnancy where the pregnant women suffers from excessive nausea and vomiting, leading to weight loss and nutritional deficits. The causes are entirely unknown. It is important to test hypotheses on infections and dietary factors, because such factors are potential targets for preventive actions. In addition, understanding the genetic basis of the disorder is important for further basic medical research. On this background, we will util ize existing resources administered by the Norwegian Institute of Public Health such as the Medical Birth Registry, The Twin Panel and the Norwegian Mother and Child Cohort Study to address the research objectives. The relative risk of HG according to inf ection with Helicobacter Pylori willl be studied with the use of a case-control study where the data collection has already been performed.