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BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Comparative effectiveness research. Ansvaret for å lede i internasjonalt prosjekt (CER)

Awarded: NOK 1.8 mill.

In 2016-2018 we carried out a systematic mapping review in order to describe the extent of, and methods used in,comparative effectiveness studies in the health services. We searched systematically for systematic reviews that summarized effects of interventions published in the period 2009 thorugh January 2017. We included 1098 systematic reviews the met out inclusion criteria. We described the distribution of these across different health care areas, based on the International Statistical Classification of Diseases and Related Health Problems (ICD-10). We further examined the distribution in relation to 2016 reports from the Global Burden of Disease Project concerning deaths and Years of Life Lost, and Years Lived With Disability. The results of our review show that 49% of the systematic reviews concern neoplasms (14%), mental and behavioural disorders (12%), diseases of the musculoskeletal system (12%), and diseases of the circulatory system (11%). Three of these disease categories constitute 20 of the 30 leading causes of death and Years of Life Lost in countries with high sociodemographic status. Infectious and parasitic diseases, and perinatal conditions dominate the list in countries with low sociodemographic index. 7% and 0%, respectively, of the included systematic reviews concerned these disease categories. Our results further show that mental and behavioural disorders and diseases of the musculoskeletal system, which constitute 24% of the included systematic reviews, represent a third of the 30 leading causes of Years Lived with Disability. These results may be of importance for the further work of the international consortium Clinical Research Initiative for Global Health (CRIGH)that the Project Comparative effectiveness Research (CER)is a part of.


Funding scheme:

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering