Back to search

BIOTEK2021-Bioteknologi for verdiskaping

FP: Bioøkfelles - Engineering the sensory quality of marine ingredients using "marine sensory enzymes"

Alternative title: aMASE

Awarded: NOK 12.1 mill.

Tailoring enzymes for the emerging biotechnology industry will be key to further development and value creation of biological resources in the bio-economy era. The last decades, the marine sector has shown great progress in generating marine ingredients, such as peptides and oils, from industrial bioprocessing of fish biomass. The marine ingredients maintain a high nutritional quality, but suffer from sensory qualities that prevent a commercial realization of high-value and high-quality products for human consumption. The fish-like odor of marine ingredients is considered the main biological barrier to reach the full economic potential in the bio-based marine sector. In this project, enzymes are explored to overcome the abovementioned biological and economic barriers. From open-sourced databases, metagenomes and positive clones from libraries, enzyme sequences have been analyzed by bioinformatics. More than 65 enzymes have been selected for investigation. The enzymes have fed into an established enzyme discovery workflow covering all aspects of the value chain from identification of genes, to recombinant production and validation by pilot trials in industrial settings. Promising candidate enzymes underwent broad biochemical and biophysical characterization using state-of-the-art methodology. Of these, three enzyme candidates were tested in marine ingredients and the chemical reaction was conceptually demonstrated. One of these enzymes is now being further developed to better suit the industrial conditions. If successful, the enzymes will allow a full commercial utilization of bio-based residual raw materials from the aquaculture and increase value creation, ultimately promoting a sustainable and profitable bio-economy.

-

Tailoring enzymes for the emerging biotechnology industry will be key to further development and value creation of biological resources in the bio-economy era. The last decades, the marine sector has shown great progress in generating marine ingredients, such as peptides and oils, from industrial bioprocessing of fish biomass. The marine ingredients maintain a high nutritional quality, but suffer from sensory qualities that prevent a commercial realization of high-value and high-quality products for human consumption. The fish-like odour of marine ingredients is considered the main biological barrier to reach the full economic potential in the bio-based marine sector. In the proposed project, enzymes will be explored to overcome the abovementioned biological and economic barriers. The enzymes will feed into an established enzyme discovery workflow covering all aspects of the value chain from identification of genes, to recombinant production and validation by pilot trials in industrial settings. If successful, the enzymes will allow a full commercial utilization of bio-based residual raw materials from the aquaculture and increase value creation, ultimately promoting a sustainable and profitable bio-economy.

Publications from Cristin

No publications found

No publications found

Funding scheme:

BIOTEK2021-Bioteknologi for verdiskaping