BIOTEK2021-Bioteknologi for verdiskaping

SuReMetS project will develop novel marine ingredients from various resources like underutilized material from fisheries and microalage targeting management of metabolic syndrome (MetS). To achieve this; novel enzymes to better process the material and access the valuable ingredients will be done in parallel. The potential beneficial human health effects of marine nutraceuticals are well established, and in particular, we believe that marine ingredients can prevent MetS. The chronic and complex nature of MetS, makes it challenging to present a single drug for long-term medications, hence the development of marine nutraceuticals can represent a safer and a better long-term option. The project use transdisciplinary approaches combining basic biosciences, public health efforts including education, and industry, to provide a better balance between how the research and industry can develop new biomarine products with the need and expectations from end-users as well as the community.

SuReMetS will develop novel marine ingredients from underutilized material from fisheries and microalgae targeting the management of metabolic syndrome (MetS). Novel enzymes with characteristics that are optimally suited to better process the starting material and access the valuable ingredients will be isolated from both individual bacteria from the surfaces of microalgae and fish, and from metagenomics libraries produced from the microbiomes of these sources, together with commercially available enzymes, which will be investigated in parallel. These enzymes will have potential utility in enzyme-assisted extraction (EAE) strategies using different types of marine biomass. Various chemical and mechanical processes are currently used for the extraction of bioactive compounds or fractions from algae; however, problems exist if the target compounds are sensitive to extraction techniques which involve heat or solvents. Thus new improved extraction processes such as the use of EAE processes, offers faster, and more efficient alternatives. The potential beneficial human health effects of marine nutraceuticals are well established, particularly the consumption of marine ingredients can help in the management of MetS. The chronic and complex nature of MetS, makes it challenging to employ a single drug for long-term medication, hence the development of marine nutraceuticals represents a safer and better long-term option. SuReMetS will involve transdisciplinary approaches combining basic biosciences, public health efforts including education and industry, to provide a better balance how the research community and industry can develop new biomarine products meeting the needs and expectations from end-users as well as the community. SuReMetS is an innovative project applying state-of-the-art methods and new technologies, such as metagenomics, HTS strategies and bioinformatic pipelines while combining research with high potential for commercialization of marine resources.