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BIA-Brukerstyrt innovasjonsarena

Hypersension 2.0

Alternative title: Hypersension 2.0

Awarded: NOK 16.0 mill.

Project Number:

332371

Project Period:

2022 - 2026

Funding received from:

Raised blood pressure is a condition affecting 1.5 million Norwegians, and it is the most important risk factor for early death. The condition causes approx. 12.8% of all deaths. Better monitoring of BP and its variations during day and night is a key action in order to identify and help individuals at risk. It is often necessary to measure BP over a period of time. However, state-of-the-art 24h BP measurements are unsatisfactory as they are limited to intermittent measurements (3-4 per hour). Also, the inflatable cuff around the upper arm may cause stress and pain, which thereby introduces error in the measurements and disturbs and limits normal daily life. When used during the night, it often leads to interrupted sleep, which may in turn result in improper measurement of blood pressure. The goal of the Hypersension 2.0 project, is to develop a wearable sensor for continuous measurements of blood pressure. The start-up company Aidee Health AS is the project owner of Hypersension. The project also consists of SINTEF Digital, a leader in sensor development and research, OUS (Oslo University Hospital), a world leader in blood pressure research and an exciting medical professional environment in Sandefjord Helsepark. Clinical professionals confirm that the product has a large market potential, both for medical offices and hospitals. Compared with today's blood pressure gauges, it is far more user friendly and it can also be used in research of various heart disease, as it provides continuous measurement and ability for thorough analysis / understanding of diseases with difficult regulated blood pressure. In this first phase of the project, we will work towards completing the sensor unit (generation 3) and model for blood pressure estimation for validation study. In parallel the project will start up user testing and based on this develop suitable user interfaces for the various roles in the Hypersension system.

Hypertension or raised blood pressure (BP) is affecting 1.5M Norwegians and is the major risk factor for early death. Better monitoring of BP and its variations is vital to identify and help individuals at risk. However, state-of-the-art 24h measurements are unsatisfactory as they are limited to point measurements and are based on an inflatable cuff around the upper arm that causes stress and pain, which thereby introduces errors in the measurements. The goal of the Hypersension 2.0 project is to develop a cuff-less wearable device (a sensor belt) that delivers BP measurements for every heartbeat. In addition, the sensor belt aims to measure and deliver other physiological data and important contextual information which affects BP such as activity level, body posture, ECG, sleeping patterns, breathing rate, skin temperature and blood oxygen saturation. Besides the wearable device, we will also develop a complete system for monitoring and safely transmitting data, making the data available both for patients and clinical professionals, thereby empowering patients in finding the optimal treatment plan in cooperation with clinical professionals. The consortium consists of complementary partners which have a close relationship from previous projects: Aidee Health AS, which originates from the research institute SINTEF and Datek AS that has developed enterprise sensors for more than 20 years. SINTEF Digital that has a wide experience in biomedical technology, optical measurements and data analysis. Oslo Universitetssykehus has world-leading clinical expertise on hypertension and blood pressure measurements. Sandefjord Helsepark that is an association of general practitioners and specialists that regularly experience the need for improved ABPM for their patients. Aidee's R&D personnel and SINTEF has expertise in developing sensor systems and complementary software solutions while the clinical partners will provide end-user involvement and perform clinical studies.

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Funding scheme:

BIA-Brukerstyrt innovasjonsarena