0 antall prosjekter

BEHANDLING-God og treffsikker diagnostikk, behandling og rehabilitering

Nasjonalt stamcelleforskningssenter i Helse Sør-Øst RHF - se også prosjektnr 230000 hvor midler for ny periode ligger.

Nasjonalt senter for stamcelleforskning ble etablert i 2008 ved Oslo universitetssykehus (Rikshospitalet) etter et direktiv fra Helsedepartementet og midler administrert av Norges Forskningsråd. Senterets primærhensikter har vært å øke tempoet i norsk stamcelleforskning, etablere en platform ...

Tildelt: kr 34,3 mill.

Prosjektperiode: 2008-2019

Sted: Innlandet

IS-BILAT-Mobilitet Norge-USA /Canada

Socio-demographic factors influencing attendance and survival of breast cancer in the Norwegian Breast Cancer Screening Program

Breast cancer is the most common cancer in women worldwide. In Norway, a total of 2694 women were diagnosed and 715 women died of breast cancer in 2003. On the basis of the results of randomised trials from New York, Canada and different studies in Sweden , the Norwegian Ministry of Health and So...

Tildelt: kr 0,28 mill.

Prosjektperiode: 2008-2008

Sted: Oslo

SYKEFRAVÆR-Forskn.om årsaker til sykefrav

Facilitating and inhibiting factors and effect of interventions in return to work for patients with neck- and low back pain

Fremmende og hemmende faktorer og effekt av intervensjon for tilbakegang til arbeid hos pasienter sykemeldt for nakke- og ryggsmerter. Hensikten med prosjektet var å undersøke faktorer som påvirker sykefravær og tilbakegang til arbeid samt effekt av intervensjon sett fra et arbeidsrelatert, b...

Tildelt: kr 10,0 mill.

Prosjektperiode: 2008-2015

Sted: Oslo

IS-STP-Statsstipendprogram, utlendinger

Suetterlin, Stefan, GB, statsstip 2008-09

...

Tildelt: kr 43 000

Prosjektperiode: 2008-2008

Sted: Oslo

FRIBIO-Biologi og biomedisin

EMBO Conference on the replication and segregation of chromosomes

We will organise a high-quality scientific meeting to exchange information in the field of chromsome replication and segregation. This field of research is important for many reasons, for the fundamental understanding of the basic aspects of cellular grow th and proliferation as well as for an un...

Tildelt: kr 0,20 mill.

Prosjektperiode: 2008-2008

Sted: Oslo

IS-NAD-Samarbeid med NORAD-land

Yosry, Mohammad egyptisk spes 2008

...

Tildelt: kr 38 100

Prosjektperiode: 2008-2008

Sted: Oslo

YFF-Yngre, fremragende forskere

The Function of Cyclin Dependent Kinases in the DNA Damage Response and Maintenance of Genome Stability

Project Summary Genome instability is one of the hallmarks of cancer. However, the mechanisms that protect the genome against spontaneous gross chromosomal rearrangements (GCRs) are not well understood. In recent years several pathways have been identifi ed that protect the genome against sponta...

Tildelt: kr 9,5 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

FRIBIO-Biologi og biomedisin

Regulation of Autophagy through two Big Protein Complexes; TORC1 and class 3 PI3K

The mammalian target of rapamycin (mTOR), a master regulator of both growth and catabolic processes, plays a central role in signal transduction pathways mediated by a variety of stress factors. Consequently, dysregulation of mTOR is found in many cancers . Recently, much attention has been focus...

Tildelt: kr 1,00 mill.

Prosjektperiode: 2008-2009

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Copy number variants and predisposition to autoimmune diseases like rheumatoid arthritis.

A novel form of genetic variation has during the last two years been recognized to be important for human phenotypes and diseases, namely copy number variations (CNVs). CNVs have so far generally been overlooked in searches for susceptibility variants for common multifactorial diseases, however ...

Tildelt: kr 3,4 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

A novel cell cycle checkpoint in fission yeast

In this project we shall further study and characterise a novel mechanism of checkpoint regulation that we have recently discovered (Tvegård et al, Genes Dev, 2007). Checkpoints are important regulators of the cell cycle and cancer development is frequent ly associated with the lack of checkpoint...

Tildelt: kr 3,0 mill.

Prosjektperiode: 2008-2013

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Cancer-targeted T cell Receptors - the next generation immunotherapeutic drugs

The aim is to generate recombinant T cell receptors that recognize cancer cells. DNA encoding the receptors form basis for novel drugs for immunotherapy of cancer. Two strategies are followed to select T cells with the desired receptors: 1) A large number of T cell clones recognizing common canc...

Tildelt: kr 3,2 mill.

Prosjektperiode: 2008-2015

Sted: Oslo

IS-NAD-Samarbeid med NORAD-land

Sallam, Abdelhamid Egyptisk stp 07/08

...

Tildelt: kr 41 500

Prosjektperiode: 2008-2008

Sted: Oslo

KLINISK-Klinisk forskning

Understanding early events in Alzheimer disease (AD) pathogenesis: Integration of molecular, functional and structural imaging

This project will develop and employ integrated imaging techniques in the longitudinal study of patients with mild cognitive impairment (MCI). We aim to study mechanisms for Alzheimer disease induction, and to determine factors predictive for cognitive de cline and conversion to dementia. Fracti...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2008-2011

Sted: Akershus

FUGE-Funksjonell genomforskn.i Norg

Development of high througput affinity protemics to search for drug targets in cancer.

Antibody array technology, mass-spectrometry and molecular biology techniques are combined to develop a new platform for screening of drug targets in cancer. The technology allows large-scale analysis of protein networks with high sample throughput. The p roject will develop large-scale analysis ...

Tildelt: kr 5,6 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

IS-BILAT-Mobilitet Norge-USA /Canada

Studies of B cell lymphomas at the single cell level

In the research group of Prof. Erlend Smeland, where I have been working for several years, we are working with normal and malignant B cells to identify genes or aberrant signaling pathways that are of importance for the pathogenesis of lymphoma. Prof. Ro nald Levy at Stanford University School o...

Tildelt: kr 0,28 mill.

Prosjektperiode: 2008-2008

Sted: Ukjent Fylke

RUSMIDDEL-Rusmiddelforskning

Twelve Step based self-help groups for substance related disorders

Substance dependency deeply influences peoples lives in complex ways. There is typically a need for treatment and rehabilitation in a long-term perspective. The public treatment systems have deficient capacity to give follow ups. This is particularly true for patients undergoing detoxification, ...

Tildelt: kr 4,0 mill.

Prosjektperiode: 2008-2012

Sted: Agder

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Molecular characterization and functional studies of human B cell lymphoma

Malignant lymphomas represent a heterogeneous group of diseases with variable clinical course. Our group aims at identifying genes/signalling pathways with prognostic, diagnostic or therapeutic potential in B cell lymphomas. We are one of 7 groups that co nstitute the newly established Centre for...

Tildelt: kr 3,2 mill.

Prosjektperiode: 2008-2013

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Role of AlkB homologs 1 and 7 (ABH1 and 7) in epigenetic reprogramming

This project is primarily based upon the intriguing phenotype and breeding pattern of mABH1 (mouse AlkB homolog 1) targeted mice. As outlined below, this dioxygenase is required for faithful embryonic development. Major developmental defects include failu re of eye, nose and limb development (Fig...

Tildelt: kr 5,1 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Frontal lobe injury and cognitive control

The main goal of this project is to investigate the neural substrate and cognitive mechanisms that are involved in a set of higher-order "executive" functions that are necessary for goal-directed thinking and behavior. At present there is no unitary model that accounts for all aspects of executi...

Tildelt: kr 4,0 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

Towards personalized therapy for breast cancer

Purpose of the project: Few protocols have so far been designed with attempts to characterize the systems biology of cancer. The objective of the project is to translate information obtained from integrative molecular analysis of material collected from i ndividual cancer patients, through valida...

Tildelt: kr 10,0 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

Oslo Animal MRI unit - a node in the FUGE NorMIC consortium

The MR technology now allows for in vivo imaging to a resolution of microns which is even less than the size of many cell types. MRI has therefore become an invaluable tool for molecular imaging and translational research. Scientists in Oslo have used the FUGE MIC animal MR unit in Trondheim unt...

Tildelt: kr 1,00 mill.

Prosjektperiode: 2008-2012

Sted: Ukjent Fylke

FUGE-Funksjonell genomforskn.i Norg

A novel checkpoint regulating the cell cycle of fission yeast

In this project we shall further study and characterise a novel mechanism of checkpoint regulation that we have recently discovered (Tvegård et al, Genes Dev, 2007). Checkpoints are important regulators of the cell cycle. Cancer development is frequently associated with the lack of checkpoints an...

Tildelt: kr 5,3 mill.

Prosjektperiode: 2008-2011

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

Cancer-targeted T cell Receptors - the next generation immunotherapeutic drugs

The aim is to generate recombinant T cell receptors (TcRs) that recognize cancer cells. DNA encoding the receptors forms basis for novel drugs for immunotherapy of cancer. Two strategies are followed to select T cells with the desired receptors: 1) T cell s that recognize common cancer proteins, ...

Tildelt: kr 5,3 mill.

Prosjektperiode: 2008-2013

Sted: Oslo

FORNY-3-Kommersialisering av FoUresultater

Infrastrukturmidler - Helse Sør-Øst 2008

Forskning er en av fire hovedoppgaver i sykehus. Helse Sør-Øst har høy vitenskapelig aktivitet med 1338 publikasjoner og 75 doktorgrader. Likevel er det, bortsett fra ved Rikshospitalet/ Radiumhospitalet, liten kultur for å omsette forskningsresultater i innovasjon. Et eksempel er Ullevål univers...

Tildelt: kr 1,5 mill.

Prosjektperiode: 2008-2008

Sted: Innlandet

KLINISK-Klinisk forskning

Rehabilitation after severe traumatic brain injury. A national multicentre study

In Norway, the annual rate of hospital admission caused by head trauma is around 200 per 100 000 inhabitants. About 15 % of the patients admitted to a neurosurgical department with traumatic brain injury, are in the severe group according to the Glasgow C oma Scale score. These patients demand in...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Opioid activated NMDA and opioid receptor mechanisms: studies of rodent and human brain using PET

The scope of the proposed project is to study the molecular mechanisms of opioid exposure. Within the financial framework, it will be focused on preclinical testing and validation as well as first human studies. Further studies depend on additional fundin g. Intentionally, opioid analgesia in p...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2007-2011

Sted: Akershus

TJENESTER-Helse- og omsorgstjenester

Hospital at home for COPD patients - an integrated care program at Akershus University Hospital

A general goal at present is better care for the chronically ill. Akershus University Hospital (Ahus) will try to realize this goal in the case of patients with chronic obstructive pulmonary disease (COPD), by implementing an integrated care program that includes early discharge from hospital in ...

Tildelt: kr 1,2 mill.

Prosjektperiode: 2007-2011

Sted: Akershus

IS-NAD-Samarbeid med NORAD-land

Tuorkey, Muobarak Egyptisk stp 07/08

...

Tildelt: kr 95 000

Prosjektperiode: 2007-2008

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Basic and clinical studies of peptide-based immunotherapy in chronic HIV-1 infection

Immune based therapies represent new, promising approaches to the treatment of chronic HIV infection, aiming to enhance the patients own specific immune response against HIV and delay the immune impairment caused by the HIV-infection. The basis for this a pplication is two patient cohorts that ha...

Tildelt: kr 0,76 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

PES-INST-Prosjektetablererstøtte EU (FoU)

Embedded sensing platform for medical

...

Tildelt: kr 99 999

Prosjektperiode: 2007-2007

Sted: Oslo