0 antall prosjekter

HAVBRUK2-Stort program for havbruksforskning

Multiple routes to B cell memory in Atlantic salmon

Virussykdommer utgjør en stor trussel for norsk oppdrettslaks og dagens kommersielle vaksiner gir begrenset beskyttelse. For å utvikle bedre virusvaksiner må vi forstå hvordan laksens immunforsvar fungerer og hvilke mekanismer som bidrar til langvarig beskyttelse. De fleste vaksinene på markedet ...

Tildelt: kr 8,0 mill.

Prosjektperiode: 2016-2022

Sted: Ukjent Fylke

HAVBRUK2-Stort program for havbruksforskning

TLR9 stimulation of naïve Atlantic salmon B cells - does it drive proliferation and Ig-secretion?

Serological memory is one of the most important mechanisms activated by the immune system when threatened by viral infections. The knowledge of how to potentiate this response may lead to development of more efficient fish viral vaccines. This is a long p rocess requiring studies on cultivated le...

Tildelt: kr 51 999

Prosjektperiode: 2015-2016

Sted: Ukjent Fylke

HAVBRUKS-Havbruk - en næring i vekst

Activation of immune mechanisms in Atlantic salmon (Salmo salar L.) by CpG oligonucleotides

Viral diseases cause severe problems for the aquaculture industry and development of efficient virus vaccines is a priority target. Cellular defence mechanisms, both innate and acquired, are especially important to combat viral infections. Therefore ident ification of adjuvants which promote stab...

Tildelt: kr 2,4 mill.

Prosjektperiode: 2006-2009

Sted: Ukjent Fylke

HAVBRUKS-Havbruk - en næring i vekst

CpG ODN as adjuvant in recombinant infectious pancreatic necrosis virus vaccines

A high priority target in current vaccinology is the identification of adjuvants that promote stable induction of Th1 immunity but with minimal side effects. Unmethylated CpG oligodinucleotides (ODNs) within specific flanking bases (referred to as CpG mot if) are relatively abundant in bacterial ...

Tildelt: kr 2,6 mill.

Prosjektperiode: 2004-2007

Sted: Ukjent Fylke

FUGE-Funksjonell genomforskn.i Norg

Protein-protein interactions between infectious pancras virus proteins and host protein

In the post-genomic area new approaches have been developed to study and characterize protein functions in cells and organisms. One such strategy is the yeast two-hybrid system that can be used to generate complete protein interactions maps. Infectious pancreatic necrosis is one o the most thre...

Tildelt: kr 7,4 mill.

Prosjektperiode: 2004-2009

Sted: Ukjent Fylke