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Dato fra ny til gammel

HAVBRUKS-Havbruk - en næring i vekst

Leptin in fish - exploring the actions of a novel hormone and its role in control of appetite, growth and puberty in Atlantic salmon and cod

In mammals, leptin is a hormone produced by adipose tissue and has been established as a key signal for regulating adiposity. Until last month (May 2005), when our collaborators at National Research Institute of Aquaculture, Mie Japan published their disc overy of the leptin gene and its expressi...

Tildelt: kr 2,8 mill.

Prosjektperiode: 2006-2009

Sted: Vestland

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Cell cycle regulation: the role of replication clamps and interacting proteins

DNA replication is executed by enzymes called polymerases. The polymerases are tethered to the DNA template by binding to so-called clamps, which are doughtnut-shaped protein complexes encircling the DNA. The clamps are being loaded onto the DNA by clamp loaders, another protein complex. All orga...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2006-2013

Sted: Oslo

FRINAT-Matematikk og naturvitenskap

Life in the volcanic crust of the early Earth: conditions, timing and depth

Over the past decade, our group has provided convincing evidence that alteration of basaltic glass in pillow lavas of modern and ancient oceanic crust is partially controlled by microbial activity. As a result, bioactivity may have important implications for global chemical fluxes and the evoluti...

Tildelt: kr 5,5 mill.

Prosjektperiode: 2006-2010

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

Metabolic processes in the anterior eye analysed by NMR spectroscpy

This project focuses on metabolic changes occurring in different structures of the eye as a result of diseases, ageing, environmental and nutritional influence. The major objective is to present metabolic profiles of human corneas, and this includes corne as during organ cultures. Because of an i...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2006-2010

Sted: Trøndelag - Trööndelage

FRIBIO-Biologi og biomedisin

Activation of Toll-like receptors of the immune system studied by atomic force microscopy and confocal microscopy

Toll-like receptors (TLRs) trigger a fast response of the immune system to microbial particles that invade our body. TLRs recognize microbial conserved structures such as CpG-DNA or certain lipopolysaccharides, and are essential for our defense against mi crobes as well as for normal inflammatory...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2006-2009

Sted: Trøndelag - Trööndelage

FRIBIO-Biologi og biomedisin

Life histories for structured populations in fluctuating environments

This project aims at extending the Classical life history theory by merging an efficient state-dependent optimization technique that works well with structured populations (dynamic programmring) with evolutionary population dynamics (adaptive dynamics). T he resulting methodology can thus find op...

Tildelt: kr 2,6 mill.

Prosjektperiode: 2006-2009

Sted: Vestland

FRINAT-Matematikk og naturvitenskap

The search of meteorite impact structures in the Fennoscandian Shield - a novel technique

This proposal outlines a new co-operation program on impact craters between the European Space Agency (ESA/ESTEC) and the universities of Oslo and Helsinki along with the geological surveys of Norway and Finland. The main aim is to develop an intelligent search program to identify hidden meteorit...

Tildelt: kr 2,1 mill.

Prosjektperiode: 2006-2010

Sted: Oslo

FRINAT-Matematikk og naturvitenskap

Event History Modeling: Causality and Interdependence

In many fields extensive data are collected repeatedly over time. The advancing computerization of society makes such detailed follow-up data increasingly available. To extract useful information from the data one needs good statistical methods; indeed ne w methods are needed, especially when it ...

Tildelt: kr 5,7 mill.

Prosjektperiode: 2006-2010

Sted: Oslo

FRINAT-Matematikk og naturvitenskap

Computability and Complexity in Type Theory

In this project we will adress problems in mathematics of interest for theoretical computer science. The project consists of two parts, Types and the Semantics of Algorithms and Complexity and Types. In the first part we will adress problems related to t he use of Scott-domains for interpreting ...

Tildelt: kr 6,2 mill.

Prosjektperiode: 2006-2010

Sted: Oslo

FRIBIO-Biologi og biomedisin

The dynamic interstitial matrix and transcapillary exchange: Normal function and pathophysiology

The focus of this application is how the extracellular matrix can influence transcapillary transport of water and protein. The separate projects are closely related and cover studies from the level of single cells and organs to the organism. The unifying concept is the hypothesis that extracellu...

Tildelt: kr 2,4 mill.

Prosjektperiode: 2006-2009

Sted: Vestland

FRINAT-Matematikk og naturvitenskap

Rare-Earth Metal-Based Ziegler-Natta Catalysts. Structure-Reactivity Relations in Homogeneous and Heterogenized Catalysts

The long-term goal of the project is to systematically study the reaction pathways and activation sequences in empirically designed multicomponent Ziegler-Natta catalysts and, based on fundamental insights, to develop more efficient polymerization catalys ts. The focus of the predominantly synth...

Tildelt: kr 3,8 mill.

Prosjektperiode: 2006-2009

Sted: Vestland

FRINAT-Matematikk og naturvitenskap

Synthesis of Agelasines, Asmarines and Analogs, and Evaluation of Their Bioactivities

Project summary Agelasines are 7,9-dialkylpurinium salts isolated from marine sponges (Agelas sp.) and asmarines are neutral purine derivatives isolated from Raspaila sp. sponges. These two classes of purine natural products are structurally related; they both contain terpenoid side chains. Up t...

Tildelt: kr 4,3 mill.

Prosjektperiode: 2006-2010

Sted: Oslo

ROMFORSK-Program for romforskning

Norwegian Participation in the Solar B satellilte

The Japanese Solar-B mission is the next major space research project in solar physics. Its purpose is to study the coupling between the fine magnetic structure in the photosphere and the dynamic processes occurring in the corona. During the last years No rway, via the Institute of Theoretical As...

Tildelt: kr 2,6 mill.

Prosjektperiode: 2006-2009

Sted: Oslo

MILJØ2015-Norsk miljøforskning mot 2015

VANN: Linking spatial breeding behaviour and population productivity in Atlantic salmon

Traditional coarse-scale analyses of population dynamics assume that individuals in a cohort experience identical densities. Yet, juvenile density is commonly influenced by the mother's decision on the spatial location of reproduction. Thus, behavioural d ecisions taken during reproduction may in...

Tildelt: kr 3,7 mill.

Prosjektperiode: 2006-2011

Sted: Trøndelag - Trööndelage

FRIMUF-Miljø- og utviklingsforskning

Integration of climate and air quality policies

Currently there is no international institutional framework that integrates both air quality and climate policies. This project will explore both the scientific basis and political feasibility of this type of cooperation. By looking at the United States, China, and the EU in particular, we explor...

Tildelt: kr 3,6 mill.

Prosjektperiode: 2006-2009

Sted: Oslo

FRIMUF-Miljø- og utviklingsforskning

Beyond the knowledge-action gap: Research as an intervention into Sri Lanka's post-crisis reconstruction

The study seeks to develop knowledge that contributes to poverty reduction and recovery of post-war/post-tsunami Sri Lanka and asks: * What knowledge is produced by humanitarian and development practitioners in a context of crisis? * What constitutes rele vant research knowledge in the given situ...

Tildelt: kr 6,1 mill.

Prosjektperiode: 2006-2011

Sted: Trøndelag - Trööndelage

FRIBIO-Biologi og biomedisin

Hemoglobin polymorphism in Atlantic cod - finally unravelling the old puzzle

...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2006-2010

Sted: Troms - Romsa - Tromssa

FRIBIO-Biologi og biomedisin

Biological Role of Regulatory Catalytic RNA in Eukaryotic Protein Gene Expression

A new main category of catalytic RNA (the GIR1 ribozyme) has been discovered and is under investigation in our laboratory. The group I-like ribozyme (GIR1; approx. 200 nt) is a unique example of a naturally occurring ribozyme with an evolved biological fu nction. GIR1 generates the 5'-end of a nu...

Tildelt: kr 2,8 mill.

Prosjektperiode: 2006-2011

Sted: Troms - Romsa - Tromssa

FRIBIO-Biologi og biomedisin

Mechanisms of hyperglycemia-induced foam cell formation and atherosclerosis in type-2 diabetes. Role of the hexosamine biosynthetic pathway

Vascular disease is the most common cause of death in people suffering from type 2 diabetes. The high risk of atherosclerotic disease in type 2 diabetes can in part be accounted for by the diabetic state per se, such as hyperglycemia. Uptake of oxidised LDL and accumulation of cholesterol esters...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2006-2009

Sted: Oslo

SIP-Strategiske instituttprogram

Kommunikasjoner, vekstkraftige regioner og regional fordeling

I denne SIP vil TØI rette fokus mot betydningen av kommunikasjonstiltak for romlig konkurranse og som forutsetning for å utvikle vekstkraftige regioner. Bakgrunnen er at regionale virkninger av infrastrukturinvesteringer er tillagt vekt både i regional- o g transportpolitikken. Programmet består ...

Tildelt: kr 3,9 mill.

Prosjektperiode: 2006-2011

Sted: Oslo

FRIHUMSAM-Fri prosj.st. hum og sam

Informal Child Migration in Europe

The project will investigate how informal networks of care constitute a social and cultural potential for children and adult caretakers who are involved in informal and illegal migration within and into Europe. The degree to which people's activities with in these networks are exposed to differen...

Tildelt: kr 6,6 mill.

Prosjektperiode: 2006-2013

Sted: Oslo

FRIBIO-Biologi og biomedisin

Molecular characterization of embryonic microenvironment that stimulates adult human hematopoietic stem cells to differentiate into neurons

Recent research from the applicant and colleagues has shown that adult human hematopoietic stem cells, derived from bone marrow biopsies, can be stimulated to differentiate into nerve cells by placing them into the injured spinal cord of a chicken embryo. The injured embryonic spinal cord regen...

Tildelt: kr 2,9 mill.

Prosjektperiode: 2006-2009

Sted: Oslo

MILJØ2015-Norsk miljøforskning mot 2015

VANN: Hybridisation between Atlantic salmon and brown trout in Gyrodactylus-infected rivers: consequences for population viability

Extremely high proportions of hybrids between Atlantic salmon and brown trout have recently been detected in rivers Vefsna and Driva. Both rivers have been infected by the parasite Gyrodactylus salaris since the 1970s, causing a dramatic decline in juveni le salmon densities. Reasons for the rema...

Tildelt: kr 0,90 mill.

Prosjektperiode: 2006-2009

Sted: Trøndelag - Trööndelage

MILJØ2015-Norsk miljøforskning mot 2015

VANN: Mapping short and long term migration pattern of North Norwegian Atlantic salmon at sea

The marine phase is assumed to have the major influence on variations in population abundances of Atlantic salmon. However, compared to the freshwater phase, knowledge of marine life-history is scare and completely lacking for most populations. In recent years, important information regarding mar...

Tildelt: kr 3,9 mill.

Prosjektperiode: 2006-2010

Sted: Ukjent Fylke

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Structural Glycobiology

The aim of the present research project is to structurally and functionally characterize the basis of protein carbohydrate recognition, with the long-term goal of engineering the carbohydrate specificity of carbohydrate binding proteins. This research fie ld is central to many cellular processes ...

Tildelt: kr 3,4 mill.

Prosjektperiode: 2006-2011

Sted: Oslo

MILJØ2015-Norsk miljøforskning mot 2015

VANN: Individual assignment of Atlantic salmon caught in the ocean region

The project aims to investigate the genetic structure of Norwegian salmon populations. The results from project will, together with results from similar ongoing projects in other European projects, be used to build a common range wide database of salmon p opulations that can be used for assigning...

Tildelt: kr 3,5 mill.

Prosjektperiode: 2006-2009

Sted: Vestland

HAVBRUKS-Havbruk - en næring i vekst

Algal toxins & polyunsaturated fatty acids: a polyketide genomic approach to safe and efficient utilisation of microalgae in bioproduction

Microalgal secondary metabolites have attracted attention for two main reasons: first, because they are source of toxins in harmful algal blooms and second, because they are potential rich source of polyunsaturated fatty acids. The dinoflagellates are hig hly diverse group of flagellated unicellu...

Tildelt: kr 3,9 mill.

Prosjektperiode: 2006-2010

Sted: Oslo

HAVBRUKS-Havbruk - en næring i vekst

Cardiomyopathy (CMS) in Atlantic salmon: pathogenesis and experimental transmissibility.

Cardiomyopathy syndrome (CMS) has been diagnosed in Norway since 1985. It affects Atlantic salmon and primarily large farmed fish in seawater that are close to harvest. The economic impact is therefore significant. In spite of the serious impact, the caus e(s) is still unknown. Infectious etiolog...

Tildelt: kr 4,0 mill.

Prosjektperiode: 2006-2010

Sted: Akershus

HAVBRUKS-Havbruk - en næring i vekst

NEW MARINE FEED RESOURCES The building of a consortium towards exploitation of un-utilised marine resources for diets to farmed fish

The farming of high priced salmonid species in the northern hemisphere focuses on the production of marine PUFA-rich fillets. In recent years, farming of marine species has increased with higher protein and lower lipid demands. The main feed ingredients, have been fish meal and oil. But predictio...

Tildelt: kr 17,3 mill.

Prosjektperiode: 2006-2010

Sted: Vestland

SIP-Strategiske instituttprogram

Where Norway receives its water from

Water in its various states is a key element of the climate system. Yet, to date no research has been done at NILU on this most important of all atmospheric trace gases and how it relates to climate. The SIP proposed here shall change this situation and e stablish hydrometeorology as a new resear...

Tildelt: kr 4,5 mill.

Prosjektperiode: 2006-2011

Sted: Akershus

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