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Dato fra ny til gammel

FRIBIO-Biologi og biomedisin

Parasites and infectious diseases in a changing world - 4th Scandinavian-Baltic Congress for Parasitology

The biennial research conference of the Scandinavian-Baltic Society for Parasitology (SBSP) is to be held at the University of Oslo, Blindern campus, and Natural History Museum, Tøyen, between the 19th and 22nd June 2011, with Professor T.A. Bakke (Natura l History Museum, University of Oslo) as ...

Tildelt: kr 44 831

Prosjektperiode: 2011-2011

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Small RNAs and DNA repair in Mycobacterium tuberculosis adaptive responses

Tuberkulose (TB) er en av verdens mest utbredte infeksjoner, som tar nesten 1.3 millioner liv og forårsaker 8.7 millioner infeksjonstilfeller årlig. Årsaken er Mycobacterium tuberculosis (Mtb), som infiserer 1/3 av verdens befolkning og har forårsaket flere dødsfall enn noen annen mikrobe. Behand...

Tildelt: kr 3,8 mill.

Prosjektperiode: 2011-2014

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Therapeutic Strategies to Interfere with Inhibition of Anti-tumor Immune Activity Mediated by Regulatory T cells

Prosjektet undersøker en type hvite blodlegemer (regulatoriske T celler) som hemmer andre T celler i immunforsvaret og justerer immunresponser. Disse regulatoriske cellene er normalt viktige for å forhindre autoimmunitet og reumatiske sykdommer. Hvis de derimot virker for sterkt kan det bidra ...

Tildelt: kr 7,8 mill.

Prosjektperiode: 2011-2015

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Defining the role of Axl in normal and malignant mammary stem cells

Metastasis accounts for >90% of cancer-related mortality. Malignant cells carry oncogenic mutations that engender uncontrolled growth and epigenetic activation of stem cell features, chemotherapeutic resistance, immune modulation and metastasis. Tumor cel l epithelial-to-mesenchymal transition (E...

Tildelt: kr 4,8 mill.

Prosjektperiode: 2011-2015

Sted: Vestland

FRIMEDBIO-Fri prosj.st. med.,helse,biol

The complement system and the CD14/TLR4/MD2 complex as targets for therapy in sepsis.

Prosjektet tar sikte på å utvikle et nytt terapeutisk regime ved tilstander hvor det medfødte immunapparatet er over-aktivert og gir opphav til alvorlig sykdom, slik man ser det ved sepsis (blodforgiftning). Vi har i tidligere studier vist at hemming av to viktige grener av immunapparatet, komple...

Tildelt: kr 8,1 mill.

Prosjektperiode: 2011-2017

Sted: Oslo

NAERINGSPH-Nærings-phd

Økt kompetanse om autoimmune sykdommer hos hund ved studier av forekomst, etiologi og behandling av viktige autoimmune sykdommer hos hund

Kloløsning er en sykdom der hundene mister klørne sine på noen måneder. Sykdommen er smertefull og nedsetter disse hundenes livskvalitet i den akutte fasen. Kloløsning er beskrevet på mange forskjellige raser, men ikke på gordon eller engelsk settere. Før ste studiet i denne doktorgraden har derf...

Tildelt: kr 1,9 mill.

Prosjektperiode: 2011-2015

Sted: Østfold

IS-BILAT-Mobilitet Norge-USA /Canada

Molecular heterogeneity of breast carcinomas; clinical implication of tumor subclones.

Breast carcinomas are considered a heterogeneous tumor type both at the clinical, pathological and molecular level, and individual tumors can display a wide range of molecular variation. Recent work separating tumor cells into subfractions based on differ entially expressed cell surface markers h...

Tildelt: kr 0,21 mill.

Prosjektperiode: 2010-2011

Sted: Oslo

IS-MOBIL-Mobilitetsprogr.f.utl.Ph.D-stu

Mechanisms of memory retrieval in the hippocampus

The discovery that hippocampal cells have location-specific activation (place cells), which is extremely reliable and observable during almost any behaviour in a moving rat made the possibility to study neuronal processes and behaviour together. Recent ad vances suggest that place is represented ...

Tildelt: kr 93 999

Prosjektperiode: 2010-2011

Sted: Ukjent Fylke

FORNY20-FORNY2020

Oxycare - Treatment for Bacteria Infected Wounds

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Tildelt: kr 2,8 mill.

Prosjektperiode: 2010-2013

Sted: Oslo

IS-MOBIL-Mobilitetsprogr.f.utl.Ph.D-stu

Medical Image Registration of 3D Datasets

This Yggdrasil proposal represents a truly multidisciplinary project consisting of two organ-specific applications - multimodal MR imaging and image registration in the study of brain-behavior relationships in cognitive aging, and motion correction of dyn amic contrast enhanced MRI for the quanti...

Tildelt: kr 0,13 mill.

Prosjektperiode: 2010-2011

Sted: Ukjent Fylke

FORNY20-FORNY2020

New lead compound for tuberculosis treatment

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Tildelt: kr 2,1 mill.

Prosjektperiode: 2010-2013

Sted: Troms - Romsa - Tromssa

FORNY20-FORNY2020

En ny telomerase kreftvaksine

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Tildelt: kr 2,8 mill.

Prosjektperiode: 2010-2012

Sted: Oslo

FORNY20-FORNY2020

Small toxic membrane peptides to treat bacterial infections

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Tildelt: kr 2,0 mill.

Prosjektperiode: 2010-2012

Sted: Oslo

FORNY20-FORNY2020

New Drugs for Treatment of Cerebral Edema 2

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Tildelt: kr 0,93 mill.

Prosjektperiode: 2010-2011

Sted: Oslo

IS-TOPP-Toppfinans. av M.Curie-stipend

Prostate research organizations-network of early stage training (PRO-NEST) - Harri Itkonen

New and recent developments have revolutionized the prostate cancer research and clinical arenas, requiring the next generation scientists to have comprehensive knowledge and expertise in basic, clinical and applied research. PRO-NEST offers young researc hers a European integrated, multi-discipl...

Tildelt: kr 0,59 mill.

Prosjektperiode: 2010-2013

Sted: Oslo

BIONÆR-Bionæringsprogram

Mapping and identification of the mutation causing Progressive Retinal Atrophy (PRA) in Shetland sheepdog

Prosjektet har hatt en god framdrift. Etter at vi tidligere i prosjektet identifiserte en genomisk region der det finnes risikogener for sykdommen har vi i 2014 og 2015 fortsatt arbeidet med å beskrive den genomiske regionen. Totalt har det vært samlet inn blodprøver fra ca 220 hunder, 31 hunder ...

Tildelt: kr 2,8 mill.

Prosjektperiode: 2010-2016

Sted: Akershus

FRIMEDBIO-Fri prosj.st. med.,helse,biol

The AlkB family of hydroxylases; unique roles in DNA, RNA and histone hydroxylation/demethylation.

This project is partly based upon the intriguing phenotype and breeding pattern of Alkbh1, Alkbh4 and Alkbh7 (AlkB homolog 1, 4 and 7) targeted mice. Alkbh1 targeting in mice cause sex-ratio distortion and asymmetric left-right eye development. Alkbh1 is highly expressed in embryonic stem (ES) c...

Tildelt: kr 6,8 mill.

Prosjektperiode: 2010-2015

Sted: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

A whole-genome approach to monogenic and type 1 diabetes: Copy-number variation and exome screening

Diabetes is an epidemically increasing, common disease with high morbidity. Recently, there has been a break-through in the identification of diabetes risk genes. Although the genome-wide association studies in type 2 diabetes have been successful in iden tifying common gene variants associated w...

Tildelt: kr 9,7 mill.

Prosjektperiode: 2010-2014

Sted: Vestland

BIONÆR-Bionæringsprogram

HESTEFORSK Immune reactivity in the intestinal mucosa of healthy horses and of horses with chronic inflammatory bowel disease (H0947249)

In the horse, the immune system of the intestine is only little explored and the knowledge of the immunopthogenesis of intestinal inflammation is poor, which is an obstacle to effective therapies. This project aims at new knowledge of (1) the normal immun ology of the intestinal lymhoid tissue an...

Tildelt: kr 0,53 mill.

Prosjektperiode: 2010-2015

Sted: Oslo

IS-MOBIL-Mobilitetsprogr.f.utl.Ph.D-stu

Hormone-dependent cancers in the female: Comparative genomics approaches in breast, ovarian, cervix and endometrial cancers

Cancer is said to be a genetic disease based on the large number of genome variations present in cancer cells. Cancers specific for women - breast, ovarian, cervical and endometrial - represent a major health problem due to their high incidence and mortal ity rates. DNA copy number alterations ...

Tildelt: kr 34 000

Prosjektperiode: 2009-2009

Sted: Ukjent Fylke

IS-BILAT-Mobilitet Norge-USA /Canada

Identification of immune cells trafficking in gingival lymphatic vessels to afferent lymph nodes during development of periodontal disease.

Lymphatic vessels are made for transportation of tissue fluid, extravasated protein and they have an important role in the body's immune defense: activated antigen presenting cells enter the initial lymphatics and are transported to lymph nodes where they stimulate T and B lymphocytes targeted f...

Tildelt: kr 0,24 mill.

Prosjektperiode: 2009-2010

Sted: Vestland

IS-MOBIL-Mobilitetsprogr.f.utl.Ph.D-stu

Global approach of transcriptome in the alveolar bone of a knock-in Msx2-/- murine model.

Vertebrate Muscle Segment homeobox genes (Msx) control development. Their functions in post-natal growth and homeostasis remain unexplored. The present project is dedicated to Msx2 in post-natal tooth and bone oral physiopathology. Arjeta Agailiu thesis (directed by Pr. Ariane Berdal) aims to p...

Tildelt: kr 21 999

Prosjektperiode: 2009-2010

Sted: Ukjent Fylke

NAERINGSPH-Nærings-phd

Development of Sonosensitive Liposomes for Drug Delivery

The main motive for developing liposomes as drug delivery systems for cytoctoxic drugs is to improve the low therapeutic-to-toxicity ratio associated wih conventional chemotherapy. The technology benefits from the well documented ability of nanoparticulat e or liposomal drugs to specifically accu...

Tildelt: kr 1,4 mill.

Prosjektperiode: 2009-2012

Sted: Oslo

IS-STP-Statsstipendprogram, utlendinger

Lorenzo Corrales, Yolanda Spania 08/09 Kulturavtalestipend

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Tildelt: kr 70 000

Prosjektperiode: 2009-2009

Sted: Oslo

IS-STP-Statsstipendprogram, utlendinger

Auner, Veronika STP 08/09 Østerrike

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Tildelt: kr 70 000

Prosjektperiode: 2009-2009

Sted: Ukjent Fylke

IS-DAAD-Forskerutveksl. Norge-Tyskland

Waldminghaus, Torsten DAADppp 2009 Tysk-norsk forskerutveksling

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Tildelt: kr 8 203

Prosjektperiode: 2009-2010

Sted: Oslo

PSYKISK-Psykisk helse

Longitudinal MRI Studies of Brain Morphology in Schizophrenia and Bipolar Disorder: Etiological Risk and Genetic Association.

Schizophrenia is often considered being a neurodevelopmental disease. The phenotype is heterogeneous with high heritability (80%) and unknown etiology and pathophysiology. Morphological brain abnormalities appear to be intrinsic features of the disease. I n previous scientific studies, abnormalit...

Tildelt: kr 5,4 mill.

Prosjektperiode: 2009-2013

Sted: Oslo

IS-DAAD-Forskerutveksl. Norge-Tyskland

Tho, Ingunn DAADppp 2008-09 Tysk-norsk forskerutveksling

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Tildelt: kr 90 000

Prosjektperiode: 2008-2010

Sted: Troms - Romsa - Tromssa

IS-AUR-Samarb.progr. Norge Frankrike

Reuter, Nathalie Aurora 2008-09 Fransk-norsk forskerutveksling

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Tildelt: kr 44 589

Prosjektperiode: 2008-2010

Sted: Vestland

IS-STP-Statsstipendprogram, utlendinger

Konig, Marton Ungarn STP07/08

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Tildelt: kr 0,10 mill.

Prosjektperiode: 2007-2008

Sted: Oslo

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