0 antall prosjekter

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Agronomic- and processing protocols in the production of sweet onions enriched in oligosaccharides and quercetin glucosides.

This project focuses on two new onion productions, aiming to increase the total onion consumption in Norway, through developing production- and postharvest protocols for two new onion productions, developing productions of onions that will be marketed bas ed on their consumer friendliness, taste ...

Tildelt: kr 10,2 mill.

Prosjektperiode: 2006-2010

Sted: Akershus

FRIMED-Klinisk medisin og folkehelse

Identification of genetic and environmental factors contributing to disease susceptibility and clinical presentation of multiple sclerosis

The aim of this project is to identify factors contributing to development of multiple sclerosis (MS) in a PhD project. MS is a debilitating inflammatory disease of the central nervous system. The etiology is unknown, but both genetic and environmental fa ctors are involved. Identification of the...

Tildelt: kr 2,0 mill.

Prosjektperiode: 2005-2009

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

From Divided Objects to Whole Subjects. Holistic Philosophy in Medicine.

In the project From Divided Objects to Whole Subjects a theoretical study shall be carried out with the aim of developing and imparting a perspective in medicine that has been given little attention in today’s medicine. This perspective is the one that co ncerns the sick person and that attempts ...

Tildelt: kr 1,9 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

PSYKISK-Psykisk helse

Risk and protective factors for psychiatric disorders and symptoms among preschoolers: A prospective community study

1.Young children have psychiatric disorders and they endure. The rate of psychiatric disorders in early childhood is between 9% and 21%, which is comparable with rates at other ages. Moreover, there is a strong continuity of disorders and symptoms from ye arly childhood into later childhood and a...

Tildelt: kr 6,1 mill.

Prosjektperiode: 2005-2010

Sted: Trøndelag - Trööndelage

PSYKISK-Psykisk helse

Suicide among children in Norway

Suicide among children below 16 years of age occurs infrequently, but in Norway this problem has been growing. Suicide ideations and threats from children are more often registered in clinical settings. There is a lack of knowledge concerning this issue i n the international community. There is a...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2005-2012

Sted: Oslo

PSYKISK-Psykisk helse

The causes and implementation of resilience

R.BUP's tasks are research and education to promote mental health in children and adolescents, with catchment area Eastern and Southern Norway. Activities focusing on resiliemce and coping have run for years. Examples are studies as: exploration of stress and resilience processess; longitudinal ...

Tildelt: kr 12,5 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

KREFT-Offentlig kreftprogram

EURAMOS- KREFT

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Tildelt: kr 0,73 mill.

Prosjektperiode: 2005-2013

Sted: Oslo

PSYKISK-Psykisk helse

Characterization of early trauma/dysmorphogenesis and adult neurodysfunction in schizophrenia – relation to adult brain morphology

Schizophrenia is considered to be a neurodevelopmental disease. Genetic factors as well as early-life environmental influences are implicated in its etiology. The aim of the doctoral project is to characterize patients with schizophrenia spectrum disorder with regard to history of obstetric comp...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

The role of Peptidyl Arginine Deiminase and protein citrullination in the pathogenesis of rheumatoid arthritis

Rheumatoid arthritis (RA) is a common multifactorial inflammatory disorder. It is characterised by a chronic synovial inflammation that destroys the affected joints and causes disability. The molecular basis of RA is largely unknown, but it is clear that the main genetic contribution to RA is by ...

Tildelt: kr 2,1 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Infections, prepregnant diet and other environmental factors as possible causes of hyperemesis gravidarum (HG).

Hyperemesis gravidarum (HG) is defined as severe, intractable nausea and vomiting in early pregnancy. The HG-patient suffers from dehydration, weight loss, ketonuri and a nutritional deficiency. HG affects 0,5-2,0% of pregnant women, and the etiology is u nknown. Until recently HG was believed to...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2005-2009

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Diet, vitamin A and K, genetics and orofacial clefts

Several factors have been shown to promote orofacial clefting eg genetic factors, teratogenes, maternal alcohol and cigarette use, herbicides and nutrient intake like folate and other B-vitamins. Our primary aim is to study the association between materna l dietary intakes of the first three mont...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

Functional studies of S100A4 - A Calcium-binding Protein with Metastasis-promoting Capacity

The calcium-binding protein S100A4 has convincingly been linked to the metastatic process, butt he exact mechanism of action is still unknown. The main purpose of the project is to study the molecular mechanisms behind some of the biological functions th at have been suggested tor the protein, a...

Tildelt: kr 7,3 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

KREFTSATS-Særutlysning kreftmidler, historikk

MOLECULAR AND BIOLOGICAL STUDIES OF CANCER METASTASIS

Metastasis, cancer spread to other organs, is the principle cause of death of cancer patients. Early detection of metastatic tumor cells, development of new treatment strategies and knowledge about how to prevent cancer metastasis are some of the most cha llenging tasks in cancer research. Our pr...

Tildelt: kr 6,0 mill.

Prosjektperiode: 2005-2009

Sted: Oslo

GNBIO-Grunnleggende næringsrettet bioteknologi

Selection and characterization of novel cancer specific antibodies – utilization in diagnostic and therapeutic approaches

Objective: The main purpose is to identify and characterize novel breast cancer specific antibodies. Interesting candidates will be thoroughly characterized for their specificity. Fulfilling the specificity criteria their potential as diagnostic or progno stic markers will be investigated. Finall...

Tildelt: kr 4,0 mill.

Prosjektperiode: 2005-2010

Sted: Ukjent Fylke

FRIMED-Klinisk medisin og folkehelse

Generation, reproduction and birth outcome

Causes for disease late in life can be found in events around birth, but also in events before the birth itself. A huge interest in the determinants of birthweight has recently re-emerged due to consistent results showing increased risk of poor health out comes for individuals born with low birth...

Tildelt: kr 2,0 mill.

Prosjektperiode: 2005-2010

Sted: Vestland

STORFORSK-Store forskerinitierte prosjekter

Adipose Stem Cells: Molecular Basis of Pluripotency

Stem cells reside in many adult tissues and are responsible for maintaining tissue homeostasis. Adipose tissue-derived mesenchymal stem cells (ASCs) display sufficient plasticity to differentiate into cell types outside their predicted developmental linea ge. This might create opportunities for a...

Tildelt: kr 18,5 mill.

Prosjektperiode: 2005-2011

Sted: Oslo

ELSA-Etiske,rettslige og samf.m. as

The moral status of human embryos with special regard to stem cell research and therapy

This is a multidisciplinary project with contributions from biology, medicine, philosophy and theology. The background for the project are the developments going on within the fields of basic and clinical research on and clinical use of human stem cells. These new biotechnological possibilities h...

Tildelt: kr 2,7 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

MATJORD-Program for forskning innenfor jordbruksog matproduksjon

Beskytter melkeprodukter mot metabolsk syndrom?

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Tildelt: kr 0,67 mill.

Prosjektperiode: 2005-2009

Sted: Oslo

PSYKISK-Psykisk helse

Communication, somatisation and alexithymia. The impact of alexithymia for the process of somatisation in context of clinical communication

Background: Chronic health complaints are prevalent in general practice and in psychiatry and are often labelled as medically unexplained symptoms (MUS). Sensitisation has been proposed as an underlying neurobiological substrate for MUS. We suggest that a deficit in affect regulation, operationa...

Tildelt: kr 2,4 mill.

Prosjektperiode: 2005-2009

Sted: Oslo

PSYKISK-Psykisk helse

Antisocial behavior at threshold of adolescence: A longitudinal study of precursors, risk and protective factors from early preschool years

Antisocial behavior among children and adolescents lead to great human costs for the youths, families, and local communities that are affected. The economical costs for the society at large are considerable. The principal objective of the current project is to contribute with knowledge about deve...

Tildelt: kr 2,2 mill.

Prosjektperiode: 2005-2013

Sted: Oslo

STORFORSK-Store forskerinitierte prosjekter

Environmental Triggers of Type 1 Diabetes: The MIDIA Study (MIDIA is the Norwegian acronym for "Environmental Triggers of Type 1 Diabetes")

Type 1 diabetes is one of the most prevalent chronic diseases in childhood, and is the end-stage of a destructive inflammation of the insulin producing beta-cells in the pancreas. The disease is caused by unknown environmental factors affecting individu als at genetic risk. In contrast to other...

Tildelt: kr 19,6 mill.

Prosjektperiode: 2005-2011

Sted: Oslo

STORFORSK-Store forskerinitierte prosjekter

The TOP study - Identification of phenotypes and genetic susceptibility in severe mental disorders

Severe mental disorders (schizophrenia and bipolar/manic-depressive disorder) are major causes of disability worldwide, and rank as some of the most costly disorders to afflict humans. The etiology still remains elusive, but there is now overwhelming evid ence that genetic factors play a prominen...

Tildelt: kr 19,9 mill.

Prosjektperiode: 2005-2011

Sted: Oslo

YFF-Yngre, fremragende forskere

Molecular portraits of breast cancer: Translating genomics to the clinical practice

By using hierarchical clustering of global gene expression data, we were the first to identify five subtypes of breast tumors characterized by specific expression patterns. Our existing work has generated a rich and unique resource and knowledgebase from which to continue research. We will apply ...

Tildelt: kr 7,4 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

YFF-Yngre, fremragende forskere

The ethics of priority setting in global health

Background: It is widely acknowledged that the distribution of scarce health care resources should satisfy two goals: allocative efficiency and fairness. However, there exist little evidence and guidance on how efficiency could be incorporated with fairne ss. This is both a theoretical problem an...

Tildelt: kr 7,0 mill.

Prosjektperiode: 2004-2011

Sted: Vestland

YFF-Yngre, fremragende forskere

Identification of phenotypes and genetic susceptibility in severe mental disorders

Severe mental disorders (schizophrenia and bipolar/manic-depressive disorder) are major causes of disability worldwide, and rank as some of the most costly disorders to afflict humans. The etiology still remains elusive, but there is now overwhelming evid ence that genetic factors play a prominen...

Tildelt: kr 8,3 mill.

Prosjektperiode: 2004-2010

Sted: Oslo

KREFTSATS-Særutlysning kreftmidler, historikk

Critical regulatory networks for tumor-vascular interactions and activated angiogenesis in urogenital cancers

Angiogenesis and tumor-vascular interactions are essential for tumor spread. We focus on this aspect since anti-angiogenic therapy avoid treatment resistance. Adhesion molecules are important for the ability of tumor cells to invade surrounding tumor stro ma and to enter the vascular systems (blo...

Tildelt: kr 6,6 mill.

Prosjektperiode: 2004-2009

Sted: Vestland

KREFTSATS-Særutlysning kreftmidler, historikk

Developmental biology of solid tumours may pave the way for advanced medicine

We study three human cancer diseases, colorectal cancer (CRC), testicular germ cell tumour (TGCT), and malignant peripheral nerve sheath tumour (MPNST), originating from different types of stem cells. All three diseases develop through morphologically def ined stages, and the stepwise molecular b...

Tildelt: kr 6,6 mill.

Prosjektperiode: 2004-2009

Sted: Oslo

PSYKISK-Psykisk helse

Anorexia nervosa: Pasientens opplevelse

Formål: Med basis i pasienters subjektive erfaring, beskrive variasjon og utvikle teoretiske modeller ("begrepskart") for å forstå psykologiske kvaliteter av sentral betydning for sekundær og tertiær forebygging og klinisk behandling av spiseforsty rrelsen anorexia nervosa (AN). Unders...

Tildelt: kr 1,7 mill.

Prosjektperiode: 2004-2011

Sted: Oslo

PSYKISK-Psykisk helse

Characterization of Brain Morphology in Schizoprenia Spectrum Disorder using Magnetic Resonance Imaging and Computer Image Analysis

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Tildelt: kr 2,9 mill.

Prosjektperiode: 2004-2009

Sted: Oslo

RUSMIDDEL-Rusmiddelforskning

Barn som har vært eksponert for rusmidler i fosterlivet: reguleringsforstyrrelser og samspillvansker i første leveår

Prosjektet innebærer en prospektiv, longitudinell undersøkelse av barn eksponert for rusmidler i fosterlivet, med spesielt fokus på reguleringsvansker og samspillsproblemer i første leveår. For å undersøke spesifisiteten av samspillsvansker hos barn ekspo nert for rusmidler i fosterlivet, blir de...

Tildelt: kr 2,4 mill.

Prosjektperiode: 2004-2011

Sted: Oslo