5 392 antall prosjekter

STAMCELLER-Stamcelleforskning

Tissue engineering in bone defects: Development of porous copolymer scaffolds stimulating stem cell growth and bone regeneration

For repair of bone defects, tissue engineering would be to combine cells capable of osteogenic activity with an appropriate scaffold. Mesenchymal stem cells are multipotential cells that are capable of differentiating into different type of cells dependin g on culture condition. The selection of ...

Tildelt: kr 3,4 mill.

Prosjektperiode: 2007-2010

Sted: Vestland

STAMCELLER-Stamcelleforskning

Genome plasticity of somatic stem cells

Chromatin organization in stem cells arises from distinct combinations of epigenetic marks resulting in genomic plasticity. Mesenchymal stem cells (MSCs) have received intense attention due to their perceived potential use in regenerative medicine. Nothin g is known, however, on epigenetic marks ...

Tildelt: kr 4,9 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

TU-Tungt utstyr

Isothermal Titration Calorimeter

An important aspect within biological chemistry research projects at the University of Stavanger (UiS) is to identify and characterize protein-protein as well as protein-nucleic acid interactions. In these projects, including signal transduction in plant nitrogen metabolism (Prof. C. Lillo), ch...

Tildelt: kr 1,3 mill.

Prosjektperiode: 2007-2009

Sted: Rogaland

SIP-NHD-Strategiske instituttprogram finansiert av NHD

Microtechnological research platform

The project utilizes the production facilities at SINTEF MiNaLab as a tool for University research. This production line is fully ISO sertified and offers state-of-the-art equipment for silicon based MEMS production. The project funds both production of d evices and training of students. The mai...

Tildelt: kr 21,0 mill.

Prosjektperiode: 2007-2010

Sted: Trøndelag - Trööndelage

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Kvalitet og mattrygghet i den pelagiske verdikjeden - verdioptimalisering gjennom økt kompetanse

Forskningsaktiviteten i det avsluttede prosjektet "Pelagisk kvalitet - fra hav til fat" har avdekket en rekke kritiske punkter, både ombord og i mottaksanlegg, som er av stor betydning for kvaliteten og mattryggheten for pelagisk fiskeråstoff. Et av de vi ktigste kriteriene for å kunne definere k...

Tildelt: kr 5,3 mill.

Prosjektperiode: 2007-2009

Sted: Ukjent Fylke

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Identification of molecular markerks associated with winter survival in the cultivated strawberry

Vinterskade i jordbær er et stort problem for norske jordbærprodusenter. Det medfører, i gjennomsnitt, en årlig avlingsreduksjon på minst 20%. Av denne grunn er foredling av jordbærsorter med bedre resistens mot frost ett av de viktigste foredlingsmål i G raminors foredlingsprogram. Skandinavia e...

Tildelt: kr 1,6 mill.

Prosjektperiode: 2007-2011

Sted: Innlandet

SIP-LMD-SIP finansiert av Landbruksog matdepartementet

Phytophthora diseases in Rosaceae: Plant resistance and plant-pathogen interactions

Each year strawberry- and raspberry producers experience serious economical losses due to fungal or oomycete diseases. In this project we will address two such diseases, strawberry crown rot (Phytophthora cactorum) and raspberry root rot (Phytophthora fra gariae var. rubi). An efficient control m...

Tildelt: kr 7,3 mill.

Prosjektperiode: 2007-2011

Sted: Akershus

SIP-LMD-SIP finansiert av Landbruksog matdepartementet

Functional genomics of wood degradation: strategies used by decay fungi against wood protection systems and natural host defence compounds

Fungal decay of wood products is a global problem that has been traditionally combated with chemical preservatives. There is currently a great demand for alternatives to contemporary chemical preservatives due to their toxicity to the environment, and the current Strategic Institute Program (SIP...

Tildelt: kr 10,1 mill.

Prosjektperiode: 2007-2010

Sted: Akershus

NANOMAT-Nanoteknologi og nye materialer

Modeling of particle deposition phenomena in heat exchangers

This project will be a Norwegian contribution to the European MATERA FOULSURFACE program, dealing the the physics of fine particle deposition in heat exchengers. The work in the proposed Norwegain activity will be on the modeling of the particle flow in t urbulent thermal boundary layers. The ma...

Tildelt: kr 1,2 mill.

Prosjektperiode: 2007-2010

Sted: Trøndelag - Trööndelage

STAMCELLER-Stamcelleforskning

Impact of DNA base lesion repair for stem cell maintenance

DNA damage (mutations) are the fundamental cause of all forms of cancer and a number of different but integrated processes operate to prevent genetic changes from occurring. These include cell cycle regulation, DNA replication, transcription, DNA repair, regulation and sanitation of nucleotide po...

Tildelt: kr 5,0 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

BIA-Brukerstyrt innovasjonsarena

A new Computed Tomography (CT) detector with color/dual-energy features and substantially reduced patient X-ray dose

Computed Tomography (CT) is one of the most important medical diagnosis tools of today. World-wide there is a waste number of installations, a strong increase in sales, and it represents consequently a big industry for the manufacturers. The X-ray detecto r in the CT is the main part of the machi...

Tildelt: kr 6,3 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

RENERGI-Fremtidens rene energisystemer

Energieffektivt og miljøvennlig CO2-varmepumpesystem for næringsbygg

Målet med prosjektet er å utvikle, bygge og demonstrere et energieffektivt og miljøvennlig varmepumpesystem med karbondioksid (CO2) som arbeidsmedium for oppvarming og kjøling av næringsbygg. Gjennom dette skal det legges et kunnskapsmessig grunnlag for n orsk produksjon av denne type systemer. D...

Tildelt: kr 0,62 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

SIP-NHD-Strategiske instituttprogram finansiert av NHD

A systems biology approach to the understanding of antibiotic production in the model organism Streptomyces coelicolor

Systems Biology aims at understanding and predicting the properties of a biological system under targeted perturbations (e.g. genetic changes or changes in the external environment) with the use of integrated data analyses and mathematical modelling. It requires a multidisciplinary approach incl...

Tildelt: kr 5,7 mill.

Prosjektperiode: 2007-2010

Sted: Trøndelag - Trööndelage

FRINAT-Matematikk og naturvitenskap

Investigation of equiaxed dendritic alloy solidification by in-situ synchrotron X-radiography and phase-field modelling

Important aspects of alloy solidification is poorly understood due to lack of means to observe the microstructure formation processes in situ during solidification. A new method, developed by the applicant, for in-situ acquisition of high resolution sync hrotron X-radiograms will be used to obta...

Tildelt: kr 6,9 mill.

Prosjektperiode: 2007-2010

Sted: Trøndelag - Trööndelage

FRIBIO-Biologi og biomedisin

Contact meeting for the Norwegian Biochemical Society

The annual meeting of the Norwegian Biochemical Society has a world-wide reputation as an excellent meeting place for scientists, both on the scientific and the social level. They have been a tremendous success and is arguably the one meeting in Norway wh ich has contributed the most to the conta...

Tildelt: kr 0,36 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Psychosocial effects and understanding of increased risk for Type 1 Diabetes

With the rapid development in biotechnology and increasing knowledge about the relation between diseases and genetic variability, we are faced with both new opportunities and new dilemmas. Onset of a disease is dependent on several factors as genetic pene trance, combinations of genotypes and env...

Tildelt: kr 2,8 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

The ecological and evolutionary significance of seed banks in Arabidopsis thaliana

Many studies of the genetic structuring of annual, selfing Arabidopsis thaliana populations on various geographical scales have been performed in recent years. Some studies conclude that local populations may contain relatively high amounts of genetic var iability both in phenotypic traits and pu...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2007-2012

Sted: Trøndelag - Trööndelage

FRIBIO-Biologi og biomedisin

Fe-S Cluster Biogenesis in Plastids and Mitochondria in Plants

Iron-sulfur (Fe-S) clusters are essential, inorganic cofactors of Fe-S proteins involved in numerous vital developmental processes. Although simple in structure Fe-S clusters are not formed spontaneously but require an intricate interplay of a number of p roteins and in plants Fe-S cluster biogen...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2007-2010

Sted: Rogaland

FRIBIO-Biologi og biomedisin

Dynamics underlying astrocyte behaviour

For a long time astrocytes, the most abundant glial cell species, have been considered passive bystanders of neural activity. The picture that is now emerging is that astrocytes are critically involved in regulating brain function. Despite extensive exper imental efforts, a thorough understanding...

Tildelt: kr 2,6 mill.

Prosjektperiode: 2007-2009

Sted: Akershus

FRIBIO-Biologi og biomedisin

Functions of hippocampus and entorhinal cortex studied with viral vectors

Modern brain imaging methods have contributed enormously to contemporary knowledge about the particular brain systems involved in specific cognitive functions. Unfortunately, mechanistic insights have lagged behind, largely because brain mapping in humans lacks the spatial resolution required to...

Tildelt: kr 1,5 mill.

Prosjektperiode: 2007-2009

Sted: Trøndelag - Trööndelage

FRIBIO-Biologi og biomedisin

Entorhinal grid cells and hippocampal memory

More than 30 years of research have pointed to the hippocampus as a key component of the brain's circuit for spatial representation. Although place-specific firing is undoubtedly the most conspicuous behavioural correlate of hippocampal principal neurons, hippocampal neurons also respond to a va...

Tildelt: kr 4,3 mill.

Prosjektperiode: 2007-2009

Sted: Trøndelag - Trööndelage

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Enhanced safety of Norwegian type dry fermented sausage with focus on enterohemorrhagic Escherichia coli

This project concerns safe production of Norwegian type dry fermented sausages (DFS). Two outbreaks in Norway this year, caused by enterohemorrhagic Escherichia coli (EHEC) and Salmonella Kedougou in DFS, emphasize the need to focus on enhanced safety of such products. Outbreaks may cause severe ...

Tildelt: kr 11,9 mill.

Prosjektperiode: 2007-2011

Sted: Akershus

BIONÆR-Bionæringsprogram

Safe grains: Mycotoxin prevention through resistant wheat and oats

In 2004 there were alarming levels of mycotoxins like DON and T-2/HT-2in Norwegian wheat and oats. In 2005 the latter levels in oats were prohibitive for e.g. horsefeed. The present proposal builds on a decade of Norwegian cereal breeding and research to introduce/identify resistance against the ...

Tildelt: kr 9,1 mill.

Prosjektperiode: 2007-2013

Sted: Akershus

PETROMAKS-Maksimal utnyttelse av petroleumsreserver

SMOOTHPIPE: Applied Surface Technology for Multiphase Pipelines

Pressure drop along the pipeline is the main obstacle to transportation of unprocessed or partly processed wellstream over long distances. Several parameters contribute to the pressure drop, e.g. liquid hold-up, precipitations, gas-liquid surface drag for ces and surface roughness. The project wi...

Tildelt: kr 7,2 mill.

Prosjektperiode: 2007-2010

Sted: Trøndelag - Trööndelage

BIONÆR-Bionæringsprogram

Technology and methods using high-density microarrays for detection of unknown genetic modifications in plants, fungi and bacteria

To ensure the safety of genetically modified organisms (GMOs) they are subjected to risk assessment prior to release into the environment and use in e.g. food production. Such known GMOs are considered to be as safe as conventional varieties. GMOs for whi ch publicly available descriptions are un...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2007-2012

Sted: Akershus

FRIBIO-Biologi og biomedisin

Competence-induced cell lysis in Streptococcus pneumoniae: Implications for horizontal gene transfer and virulence

Streptococcus pneumoniae have the ability to enter a transient phenotype termed competence for natural transformation, which enables the bacterial cells to take up free DNA from the surrounding environment. Recently, it was discovered that competent cells also aquire the ability to lyse neighbou...

Tildelt: kr 2,4 mill.

Prosjektperiode: 2007-2010

Sted: Akershus

BIA-Brukerstyrt innovasjonsarena

Produksjon av solbeskyttende karotenoider fra bakterier.

Produksjon av solbeskyttende karotenoider fra bakterier. De fleste solkremer beskytter dårlig mot stråling ved 360-500 nm (langbølget UVA og synlig blått lys), selv om det i de senere år er blitt fokusert også på disse bølgelengdene i forbindelse med mela nom hudkreft, fotoaldring og andre solind...

Tildelt: kr 6,8 mill.

Prosjektperiode: 2007-2010

Sted: Akershus

FRIBIO-Biologi og biomedisin

Metabolic scaling in teleosts

Metabolic scaling is a widely recognised problem in biology. The underlying causes for the disproportionate relationship between the metabolic rate of an organism and its body size have long puzzled scientists, and continue to be controversial. In recent years this fascinating subject has been tr...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2007-2010

Sted: Vestland

FRIBIO-Biologi og biomedisin

New therapeutic principles and biological mechanisms related to brain tumour cell invasion and angiogenesis

Primary gliomas represent one of the greatest challenges in neuro-oncology. Recent studies have identified so-called ?cancer stem cells? in several cancers. These cells have the capacity to proliferate and establish tumors in laboratory animals after inje ction of only a small number of cells. Mo...

Tildelt: kr 1,5 mill.

Prosjektperiode: 2007-2009

Sted: Vestland

FRIBIO-Biologi og biomedisin

Vaccine development for HIV and influenza

Aim: Based on the vaccibody principle developed by us, we wish to generate novel vaccines for important infectious diseases such as HIV and influenza. Background: Vaccination has had an enormous impact on health and longevity of humans world-wide. However , for some important diseases such as HIV...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2007-2010

Sted: Oslo