1 027 antall prosjekter

PSYKISK-Psykisk helse

Longitudinal MRI Studies of Brain Morphology in Schizophrenia and Bipolar Disorder: Etiological Risk and Genetic Association.

Schizophrenia is often considered being a neurodevelopmental disease. The phenotype is heterogeneous with high heritability (80%) and unknown etiology and pathophysiology. Morphological brain abnormalities appear to be intrinsic features of the disease. I n previous scientific studies, abnormalit...

Tildelt: kr 5,4 mill.

Prosjektperiode: 2009-2013

Sted: Oslo

PSYKISK-Psykisk helse

Mothers of children with congenital heart disease (CHD): psychosocial problems from pregnancy through child age 3 years

Background: Mothers that are pregnant with, give birth to and take care of an infant with congenital heart disease (CHD) are at risk to develop serious psychological and social problems. Today, advanced surgery saves the life of ever more severely affecte d children with CHD. Yet, we know little ...

Tildelt: kr 6,4 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

PSYKISK-Psykisk helse

Ethnicity and mental health among youths: a longitudinal project

The research project will investigate social factors that may affect the development of mental health among youths from ethnic minority groups and from the majority population, with analyses distinguishing between the genders. Data will be collected in Dr ammen. Research indicates that perceived...

Tildelt: kr 2,4 mill.

Prosjektperiode: 2008-2011

Sted: Oslo

PSYKISK-Psykisk helse

Long term effects of early intervention in psychosis: Ten year follow-up of the TIPS study.

Mental illness is now the largest cause of disability in the developed countries, and schizophrenia is ranked among the leading causes of the total burden of disease worldwide. In addition to personal suffering, the disorder also represents a major proble m to society In spite of more than 75 000...

Tildelt: kr 1,9 mill.

Prosjektperiode: 2008-2011

Sted: Oslo

PSYKISK-Psykisk helse

Depression in adolescence. Precursors and developmental pathways from 18 months to 18 years.

The purpose of the project is to identify precursors, early predictors and developmental pathways to symptoms of depression in adolescence. We will also investigate gender differences related to development of mental health. The proposed project is base d on a longitudinal, prospective populati...

Tildelt: kr 3,1 mill.

Prosjektperiode: 2008-2011

Sted: Oslo

PSYKISK-Psykisk helse

Longitudinal studies of Major Depression Disorder and cognitive functioning and emotional information processing: predictors for relapse?

Kognitiv funksjon hos pasienter som opplever sin første episode av depresjon: Det foreliggende prosjektet har inkludert en gruppe mennesker som opplever å bli deprimert for første gang i sitt liv, og undersøkt kognitive funksjoner hos denne gruppen samm enliknet med en gruppe som ikke har vært d...

Tildelt: kr 3,2 mill.

Prosjektperiode: 2008-2015

Sted: Vestland

PSYKISK-Psykisk helse

Preschool ADHD: Early characteristics, developmental trajectories, risk and protective factors in a prospective birth cohort

Background: ADHD is highly prevalent, characterized by age inappropriate levels of inattention, hyperactivity and impulsiveness. It represents a substantial threat to healthy social and academic development, and increased risk for psychiatric comorbidity. Knowledge about early characteristics, d...

Tildelt: kr 4,3 mill.

Prosjektperiode: 2008-2015

Sted: Oslo

PSYKISK-Psykisk helse

Effectiveness of group and individual treatment of childhood anxiety disorders in ordinary community clinics. A randomized controlled trial.

Anxiety disorders (ADs) in childhood are common, may cause great suffering, and may persist into adulthood. Few children with an AD receive psychiatric treatment for their illness compared to children with ADHD and behavorial disorders. Knowledge of effec tive treatments and predictors of positiv...

Tildelt: kr 6,4 mill.

Prosjektperiode: 2008-2013

Sted: Oslo

PSYKISK-Psykisk helse

Suicidal behaviour in a cultural perspective

Although research on suicidal behaviour is quite abundant, we are still far from reaching a full understanding of the meaning(s) of such behaviour. In pursuit of this goal, we need to take cultural aspects into consideration. Two approaches to study the m eaning(s) of suicidal behaviour is to loo...

Tildelt: kr 3,6 mill.

Prosjektperiode: 2008-2011

Sted: Trøndelag - Trööndelage

PSYKISK-Psykisk helse

"Maternal leave, cash benefit and infant psychological difficulties: a longitudinal baseline study of 34 000 0-18 months old"

The extent to which homecare or day-care for infants may be beneficial or detrimental for subgroups of infants may depend on the family environment. The primary goal of this project will be to provide new information on childcare and infants? adaptation d uring the first 18 months of life. The pr...

Tildelt: kr 3,7 mill.

Prosjektperiode: 2008-2011

Sted: Oslo

PSYKISK-Psykisk helse

Immunity-linked genes in cognition and schizophrenia

Epidemiological data has clearly identified immune challenges during fetal and early life as a risk factor for developing psychiatric disorders such as schizophrenia and autism. Traditionally the brain was believed to be devoid of immunological responses as its ability to respond by the classical...

Tildelt: kr 5,0 mill.

Prosjektperiode: 2008-2010

Sted: Vestland

PSYKISK-Psykisk helse

Resource-oriented music therapy for psychiatric patients with low therapy motivation: Randomised controlled trial

Background Previous research has shown positive effects of music therapy for people with schizophrenia and other mental disorders. In clinical practice, music therapy is often offered to psychiatric patients with low therapy motivation, but little resear ch exists about this population. The aim ...

Tildelt: kr 6,1 mill.

Prosjektperiode: 2008-2011

Sted: Vestland

PSYKISK-Psykisk helse

Adolescent Mental Health: A Prospective Family Study

The aim of the research project is to improve the understanding of the social processes for developing mental health problems, such as depression and anxiety among Norwegian adolescents. Further, we want to examine the risk and protective factors such as social network, parental characteristica, ...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

PSYKISK-Psykisk helse

Utilizing the Internet to deliver mental health self-help interventions to underserved populations in rural areas

The overall objective of this project is to contribute to the knowledge necessary in developing effective Internet-based self-help programs for preventing mental health problems and new episodes. This will be accomplished through two complementary PhD sub -projects based on data from a randomized...

Tildelt: kr 4,5 mill.

Prosjektperiode: 2007-2014

Sted: Troms - Romsa - Tromssa

PSYKISK-Psykisk helse

Social Change, Health Care Intervention and Suicidality. - A Longitudinal Prospective Study of Suicidal behaviour.

1) Background Due to the lack of national statistics on suicide attempts in Norway, few studies have been published regarding the development of suicide attempts in the population. Since a main suicide prevention strategy in Norway is to provide follow-up for suicide attempters, there is a need ...

Tildelt: kr 2,2 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

PSYKISK-Psykisk helse

Mental disorders and developmental deviations in children (6-36 months) with congenital heart disease (CHD): a prospective case-control stud

Background: Congenital heart disease (CHD) occurs among 0.5-1.0% of newborns. Treatment possibilities have been dramatically improved during the past decade, leading to increased survival rates. How-ever, previous studies in CHD survivors suggest a higher risk of mental disorders, such as anxiet...

Tildelt: kr 5,3 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

PSYKISK-Psykisk helse

Folate and fatty acids in early life and neurodevelopmental disorders: developmental language delay as an early marker

We intend to study the relationship between intake of folate and fatty acids during early life and the risk of neurodevelopmental disorders (ND) such as autism and attention deficit/ hyperactivity disorder (ADHD). Having language problems at the age of three is a strong predictor for neurodevel...

Tildelt: kr 5,2 mill.

Prosjektperiode: 2007-2013

Sted: Oslo

PSYKISK-Psykisk helse

EARLY BIPOLAR DISORDER: CLINICAL AND BIOLOGICAL CHARACTERISTICS IN FIRST EPISODE MANIA

Bipolar disorder (BPD) is a severe psychiatric disorder characterized by manic and depressive episodes with periods of normal mood in between. Recent lines of evidence suggest that BPD is a more severe illness that previously believed and it is regarded as one of the most important factors contr...

Tildelt: kr 4,7 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

PSYKISK-Psykisk helse

Anxiety disorders in children- association with neurodevelopmental delay/disorder and temperament/personality. A clinical case-control study

Anxiety disorders (AD's) in childhood are common and may cause great suffering.Childhood AD's may persist into adulthood and knowledge of important risk factors for development and maintenance of these disorders is essential.The development of AD's is due to a complex interaction between biologi...

Tildelt: kr 5,4 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

PSYKISK-Psykisk helse

Integrating psychotherapy research and research on psychotherapy training

A promising line of research to improve the general effectiveness and efficacy of psychotherapy and to reduce dropout is to focus on the investigation of alliance formation and repair of alliance ruptures. This study draws upon five essential components: (1) focus on interpersonal process; (2) th...

Tildelt: kr 3,0 mill.

Prosjektperiode: 2007-2015

Sted: Oslo

PSYKISK-Psykisk helse

Chronic skin diseases, depression, self-esteem and body image among adolescents in Oslo

Negative self-evaluation is central in the maintenance of depression, and low self-esteem among depressed individuals is described with experienced feelings of inadequacy, inferiority, worthlessness and incompetence. Self-esteem related to body image is s alient among adolescents especially femal...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2006-2010

Sted: Oslo

PSYKISK-Psykisk helse

Major depression, cognitive function and cortisol

Our knowledge of the relationships between depression, cortisol levels and daily cortisol profiles, and cognitive impairment in a long-term perspective is scant. We aim to study these relationships over two years in patients with MDD diveded in to subgrou ps of patients with a first time episode,...

Tildelt: kr 3,0 mill.

Prosjektperiode: 2006-2014

Sted: Vestland

PSYKISK-Psykisk helse

The effects of serotonin polymorphisms and gender on cognitive control and brain function in major depression and healthy subjects.

Major depressive disorders (MDD) present a significant mental health concern to individuals and to our society and there is strong evidence that women are diagnosed with MDD twice as much as men. Cognitive functioning is the main outcome variable of this project. However, there is a considerable ...

Tildelt: kr 3,3 mill.

Prosjektperiode: 2006-2011

Sted: Oslo

PSYKISK-Psykisk helse

Phenotyping of adolescents with bipolar disorder and with schizophrenia in a longitudinal study

The currently used categorical ICD-10 and DSM-IV diagnoses play an important part in many areas of clinical psychiatry and psychiatric research. However, recent focus in genetic research on the severe mental disorders increases the need for theoretical co nstructs that are more precise descriptio...

Tildelt: kr 0,72 mill.

Prosjektperiode: 2006-2008

Sted: Vestland

RUSMIDDEL-Rusmiddelforskning

The Karolinska Project for Early Treatment of Women with Alcohol Addiction (EWA). Mortality and Morbidity 15-25 years after treatment

Summary: This is a unique, prospective longitudinal study of 420 women with alcohol addiction who were treated within a specialized woman only treatment program (EWA) that was started in 1981. Based on a randomised design, 100 of the eligible women were t reated at EWA, while another 100 were ref...

Tildelt: kr 3,8 mill.

Prosjektperiode: 2006-2011

Sted: Ukjent Fylke

PSYKISK-Psykisk helse

Family-based Treatment of Depressed Adolescents: An Empirical Study with Norwegian Adolescents in Specialty Mental Health Care

Depression disorder affects 9-11% of Norwegian and Scandinavian adolescents. The prevalence is higher (61%) for those in mental health care. Depression and affective disorders in adolescence have negative consequences for the individual, family and the so ciety at large. There is an emerging body...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2006-2009

Sted: Rogaland

PSYKISK-Psykisk helse

Supporting Patient Communication and Coping with Illness in Childhood Cancer

Children with cancer experience complex physical, psychosocial, and behavioural symptoms/problems due to the illness treatment, uncertain diagnosis, and medical procedures. To help children cope with their problems and prevent psychological distress, we d eveloped the support system, Peds-CHOICE,...

Tildelt: kr 3,7 mill.

Prosjektperiode: 2006-2011

Sted: Oslo

RUSMIDDEL-Rusmiddelforskning

Alcohol problems and depression: A 15-year longitudinal, nationwide study of mental health among Norwegian doctors.

Background: Concurrent depressive disorder and abuse of alcohol is common in the general population, and longitudinal studies that clarify this interplay over time and identify risk factors are highly required. Health care workers and in particular doctor s show high levels of depressive symptoms...

Tildelt: kr 4,2 mill.

Prosjektperiode: 2006-2012

Sted: Oslo

PSYKISK-Psykisk helse

Effects of integrated and comprehensive treatment to persons with mental disorders and substance use disorders.

Patients with co-occurring substance abuse and mental disorders are characterized by high suicide and treatment drop-out rates, and long-lasting interpersonal, work, school, health and legal problems. And because mental disorders and substance misuse inte ract and co-excists, it is important to p...

Tildelt: kr 4,7 mill.

Prosjektperiode: 2006-2009

Sted: Trøndelag - Trööndelage

PSYKISK-Psykisk helse

SUSCEPTIBILITY GENES FOR SCHIZOPHRENIA AND BIPOLAR DISORDER: TRANSLATING FUNCTIONAL GENOMICS TO CLINICAL PSYCHIATRY.

Schizophrenia (SCZ) and bipolar (BP) disorder are severe mental disorders, which are both ranked among the leading causes of the total burden of diseases worldwide. Despite decades of research devoted to psychotic illnesses, the understanding of underlyin g biological mechanisms is inadequate and...

Tildelt: kr 5,2 mill.

Prosjektperiode: 2006-2010

Sted: Vestland