PSYKISK-Psykisk helse

Suicide among children in Norway

Suicide among children below 16 years of age occurs infrequently, but in Norway this problem has been growing. Suicide ideations and threats from children are more often registered in clinical settings. There is a lack of knowledge concerning this issue i n the international community. There is a...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2005-2012

Sted: Oslo

PSYKISK-Psykisk helse

The causes and implementation of resilience

R.BUP's tasks are research and education to promote mental health in children and adolescents, with catchment area Eastern and Southern Norway. Activities focusing on resiliemce and coping have run for years. Examples are studies as: exploration of stress and resilience processess; longitudinal ...

Tildelt: kr 12,5 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

KREFT-Offentlig kreftprogram

EURAMOS- KREFT

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Tildelt: kr 0,73 mill.

Prosjektperiode: 2005-2013

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Diet, vitamin A and K, genetics and orofacial clefts

Several factors have been shown to promote orofacial clefting eg genetic factors, teratogenes, maternal alcohol and cigarette use, herbicides and nutrient intake like folate and other B-vitamins. Our primary aim is to study the association between materna l dietary intakes of the first three mont...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

PSYKISK-Psykisk helse

Antisocial behavior at threshold of adolescence: A longitudinal study of precursors, risk and protective factors from early preschool years

Antisocial behavior among children and adolescents lead to great human costs for the youths, families, and local communities that are affected. The economical costs for the society at large are considerable. The principal objective of the current project is to contribute with knowledge about deve...

Tildelt: kr 2,2 mill.

Prosjektperiode: 2005-2013

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Generation, reproduction and birth outcome

Causes for disease late in life can be found in events around birth, but also in events before the birth itself. A huge interest in the determinants of birthweight has recently re-emerged due to consistent results showing increased risk of poor health out comes for individuals born with low birth...

Tildelt: kr 2,0 mill.

Prosjektperiode: 2005-2010

Sted: Vestland

STORFORSK-Store forskerinitierte prosjekter

Adipose Stem Cells: Molecular Basis of Pluripotency

Stem cells reside in many adult tissues and are responsible for maintaining tissue homeostasis. Adipose tissue-derived mesenchymal stem cells (ASCs) display sufficient plasticity to differentiate into cell types outside their predicted developmental linea ge. This might create opportunities for a...

Tildelt: kr 18,5 mill.

Prosjektperiode: 2005-2011

Sted: Oslo

GNBIO-Grunnleggende næringsrettet bioteknologi

Selection and characterization of novel cancer specific antibodies – utilization in diagnostic and therapeutic approaches

Objective: The main purpose is to identify and characterize novel breast cancer specific antibodies. Interesting candidates will be thoroughly characterized for their specificity. Fulfilling the specificity criteria their potential as diagnostic or progno stic markers will be investigated. Finall...

Tildelt: kr 4,0 mill.

Prosjektperiode: 2005-2010

Sted: Ukjent Fylke

STORFORSK-Store forskerinitierte prosjekter

Environmental Triggers of Type 1 Diabetes: The MIDIA Study (MIDIA is the Norwegian acronym for "Environmental Triggers of Type 1 Diabetes")

Type 1 diabetes is one of the most prevalent chronic diseases in childhood, and is the end-stage of a destructive inflammation of the insulin producing beta-cells in the pancreas. The disease is caused by unknown environmental factors affecting individu als at genetic risk. In contrast to other...

Tildelt: kr 19,6 mill.

Prosjektperiode: 2005-2011

Sted: Oslo

STORFORSK-Store forskerinitierte prosjekter

The TOP study - Identification of phenotypes and genetic susceptibility in severe mental disorders

Severe mental disorders (schizophrenia and bipolar/manic-depressive disorder) are major causes of disability worldwide, and rank as some of the most costly disorders to afflict humans. The etiology still remains elusive, but there is now overwhelming evid ence that genetic factors play a prominen...

Tildelt: kr 19,9 mill.

Prosjektperiode: 2005-2011

Sted: Oslo

YFF-Yngre, fremragende forskere

Molecular portraits of breast cancer: Translating genomics to the clinical practice

By using hierarchical clustering of global gene expression data, we were the first to identify five subtypes of breast tumors characterized by specific expression patterns. Our existing work has generated a rich and unique resource and knowledgebase from which to continue research. We will apply ...

Tildelt: kr 7,4 mill.

Prosjektperiode: 2005-2010

Sted: Oslo

KREFTSATS-Særutlysning kreftmidler, historikk

MOLECULAR AND BIOLOGICAL STUDIES OF CANCER METASTASIS

Metastasis, cancer spread to other organs, is the principle cause of death of cancer patients. Early detection of metastatic tumor cells, development of new treatment strategies and knowledge about how to prevent cancer metastasis are some of the most cha llenging tasks in cancer research. Our pr...

Tildelt: kr 6,0 mill.

Prosjektperiode: 2005-2009

Sted: Oslo

YFF-Yngre, fremragende forskere

Identification of phenotypes and genetic susceptibility in severe mental disorders

Severe mental disorders (schizophrenia and bipolar/manic-depressive disorder) are major causes of disability worldwide, and rank as some of the most costly disorders to afflict humans. The etiology still remains elusive, but there is now overwhelming evid ence that genetic factors play a prominen...

Tildelt: kr 8,3 mill.

Prosjektperiode: 2004-2010

Sted: Oslo

KREFTSATS-Særutlysning kreftmidler, historikk

Critical regulatory networks for tumor-vascular interactions and activated angiogenesis in urogenital cancers

Angiogenesis and tumor-vascular interactions are essential for tumor spread. We focus on this aspect since anti-angiogenic therapy avoid treatment resistance. Adhesion molecules are important for the ability of tumor cells to invade surrounding tumor stro ma and to enter the vascular systems (blo...

Tildelt: kr 6,6 mill.

Prosjektperiode: 2004-2009

Sted: Vestland

KREFTSATS-Særutlysning kreftmidler, historikk

Developmental biology of solid tumours may pave the way for advanced medicine

We study three human cancer diseases, colorectal cancer (CRC), testicular germ cell tumour (TGCT), and malignant peripheral nerve sheath tumour (MPNST), originating from different types of stem cells. All three diseases develop through morphologically def ined stages, and the stepwise molecular b...

Tildelt: kr 6,6 mill.

Prosjektperiode: 2004-2009

Sted: Oslo

PSYKISK-Psykisk helse

Characterization of Brain Morphology in Schizoprenia Spectrum Disorder using Magnetic Resonance Imaging and Computer Image Analysis

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Tildelt: kr 2,9 mill.

Prosjektperiode: 2004-2009

Sted: Oslo

PSYKISK-Psykisk helse

PsyGutNet - Forskningsnettverk om psykobiologiske aspekter av gastrointestinale lidelser

Magetarmlidelser representerer en stor belastning for det norske helsevesenet til tross for betydelig fremgang de siste årene. I tillegg til de rene patofysiologiske årsakene til disse lidelsene, finnes det god dokumentasjon for at psykologiske faktorer e r viktig både med hensyn til insidens og ...

Tildelt: kr 0,61 mill.