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Dato fra ny til gammel

RUSMIDDEL-Rusmiddelforskning

Pilot study: prevalence of alcohol and drugs at the workplace

Alcohol and drug abuse affects society in many ways, e.g., health, social relations, safety, and productivity at the workplace. Alcohol is more significant in this respect than drugs because the use of alcohol is common and accepted by society. Testing of oral fluid (saliva) may be used to dete...

Tildelt: kr 1,00 mill.

Prosjektperiode: 2008-2009

Sted: Oslo

MILPAAHEL-Miljøpåvirkning og helse

Hearing loss and tinnitus: genetic and environmental effects

Depending on the criteria used 1/3 - 1/6 of the population experience hearing impairment. Tinnitus is defined as the sensation of sound without any outer sound stimulus present. Environmental risk factors such as noise exposure are frequently described fo r both the diseases. A genetic component ...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2008-2015

Sted: Oslo

PSYKISK-Psykisk helse

Preschool ADHD: Early characteristics, developmental trajectories, risk and protective factors in a prospective birth cohort

Background: ADHD is highly prevalent, characterized by age inappropriate levels of inattention, hyperactivity and impulsiveness. It represents a substantial threat to healthy social and academic development, and increased risk for psychiatric comorbidity. Knowledge about early characteristics, d...

Tildelt: kr 4,3 mill.

Prosjektperiode: 2008-2015

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Diabetes and diabetes precursors: detection, classification, prediction, genetics, complications and prevention. The Tromsö Study.

The incidence and prevalence of diabetes mellitus are increasing in many populations, and diabetes is now one of the most prevalent chronic diseases worldwide. Diabetes carries a great disease burden in terms of morbidity, mortality and costs. Most cases are classified as Type 2 diabetes, which h...

Tildelt: kr 3,0 mill.

Prosjektperiode: 2008-2011

Sted: Troms - Romsa - Tromssa

PSYKISK-Psykisk helse

Folate and fatty acids in early life and neurodevelopmental disorders: developmental language delay as an early marker

We intend to study the relationship between intake of folate and fatty acids during early life and the risk of neurodevelopmental disorders (ND) such as autism and attention deficit/ hyperactivity disorder (ADHD). Having language problems at the age of three is a strong predictor for neurodevel...

Tildelt: kr 5,2 mill.

Prosjektperiode: 2007-2013

Sted: Oslo

FOLKEHELSE-Folkehelse

Physical activity and chronic pain in HUNT 3 - A prospective cohort study

Regular physical activity promotes health. An inactive lifestyle may alter gene expression, influence negatively on several organ systems and thereby cause chronic disease and increase mortality. These conditions may be reversed by regular activity and in creased level of physical fitness. Physic...

Tildelt: kr 5,0 mill.

Prosjektperiode: 2007-2011

Sted: Trøndelag - Trööndelage

FRIMED-Klinisk medisin og folkehelse

Statistical modelling for infectious disease

We want to build a viable research group in statistical and mathematical modelling of infectious disease. We wish to make important original contributions to statistical methodology for analysis on infectious disease data, for the further purpose of aidin g, monitoring and understanding the sprea...

Tildelt: kr 2,8 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

FOLKEHELSE-Folkehelse

Past and current physical activity levels and the risk of fracture in a population based study with 25 years follow-up

Norway has the highest fracture incidence in the world, and data from Oslo indicate increasing incidence in both sexes to the end of 1990. Physical activity stimulate bone formation during growth and maintain bone strength and reduce bone loss in adulthoo d and old age. Physical activity througho...

Tildelt: kr 3,6 mill.

Prosjektperiode: 2007-2011

Sted: Troms - Romsa - Tromssa

MILGENHEL-Miljø, gener og helse

Cardiovascular morbidity and mortality: Effects of noise or air pollution or both?

Since road traffic is a source of both air pollutants and noise, it is very important to disentangle the health effects of the two very different types of environmental exposures related to road traffic. There are indications that both noise and air pollu tion are associated with increased risk o...

Tildelt: kr 2,9 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Psychosocial effects and understanding of increased risk for Type 1 Diabetes

With the rapid development in biotechnology and increasing knowledge about the relation between diseases and genetic variability, we are faced with both new opportunities and new dilemmas. Onset of a disease is dependent on several factors as genetic pene trance, combinations of genotypes and env...

Tildelt: kr 2,8 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Pregnancies and cancer risk - a prospective study based on Norwegian register data

In this project, associations between pregnancies and cancer risk will be examined. Focus will be on cancer forms known to be hormone-related, and also on some cancer types with less evidence for being susceptible to hormonal exposure. Our study is based on information from the Population registe...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2007-2010

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

Retinopathy and AMD in a general population. The Tromsø Study 2007.

The Tromsø VI survey is scheduled to take place October 2007- through 2008. A total of 11,000 - 16,000 adults in Tromsø will be invited (depending on funding). Many of those have participated in previous surveys, and data from those surveys will be used f or longitudinal analyses. As a subproject...

Tildelt: kr 1,4 mill.

Prosjektperiode: 2007-2010

Sted: Troms - Romsa - Tromssa

FRIMED-Klinisk medisin og folkehelse

Gene-environment interaction analyses and oral clefts in Norway

Norway has several large epidemiological studies with genetic bio-banks that may be used in etiologic research. Examples are the CONOR-cohort and the MoBa-cohort of children with mothers and fathers. Optimal analysis of such studies requires integration o f both genetic and environmental effects....

Tildelt: kr 2,8 mill.

Prosjektperiode: 2007-2011

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

THE HORDALAND WOMEN'S COHORT STUDY. A planned 15-year (1997-2012) follow up incidence study of urinary incontinence, and associated factors

Urinary incontinence (UI) is a common condition with a prevalence of about 25% of adult women, that affects the physical, psychosocial, and economic well-being. Longitudinal studies of incidence, remission and natural history are scarce. The Hordaland wo men's cohort study is an ongoing 15-year ...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2007-2011

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

Exposure expression profiles in a prospective cancer study - The Norwegian Women and Cancer postgenome cohort

From 1991 women in Norway has been recruited to participate in NOWAC by postal questionnaires. They are drawn at random from the population through the central person register. Follow-up on cancer and death is based on linkage to national registers. Altog ether 150 000 women aged 30-70 years at r...

Tildelt: kr 1,6 mill.

Prosjektperiode: 2007-2010

Sted: Troms - Romsa - Tromssa

FOLKEHELSE-Folkehelse

Is osteoporosis related to the risk of atherosclerosis and cardiovascular disease?

Cardiovascular disease (CVD) and osteoporosis are major causes of morbidity and mortality among elderly people. The two conditions have generally been considered unrelated. However, studies have indicated that arterial calcification is an active, organise d, regulated process similar to bone mine...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2006-2009

Sted: Troms - Romsa - Tromssa

MILGENHEL-Miljø, gener og helse

Food from the sea - health effects of organic pollutants and essential nutrients from marine food. The Norwegian Women and Cancer Study.

In the Norwegian Women and Cancer study (NOWAC), detailed dietary information is available in addition to a large biobank. Altogether 68 000 women aged 41-70 years at recruitment have been followed up for cancer incidence and mortality through linkages to national registers based on the unique n...

Tildelt: kr 2,7 mill.

Prosjektperiode: 2006-2009

Sted: Troms - Romsa - Tromssa

FOLKEHELSE-Folkehelse

The Hordaland Homocysteine and Health Studies - biobanks and follow-up studies

This is a joint application to cover staff (0.5 position) for project and data management, statistical and laboratory services plus running project expences for the Hordaland Homocysteine Study and the Hordaland Health Study. The Norwegian Research Counci l has previously provided such support an...

Tildelt: kr 2,0 mill.

Prosjektperiode: 2006-2009

Sted: Vestland

FOLKEHELSE-Folkehelse

The epidemiology of prescription drug use. A record-linkage study in Norway

Three surveys will form the basis of this project: a) The Cardiovascular Survey Progamme in Norway 1972-2004, b) The Youth part of a) 2000-2004, c) Norwegian Epidemiological Osteoporosis Studies (NOREPOS) 1994-2001. The information in these databases wil l be supplemented with information on soc...

Tildelt: kr 4,4 mill.

Prosjektperiode: 2006-2010

Sted: Oslo

MILPAAHEL-Miljøpåvirkning og helse

The Nordic-Swiss Childhood Brain Tumour Study

During the last decade, the use of mobile telephones has increased dramatically in large parts of the world. It has been hypothesized, that children should be more vulnerable to radio frequency electromagnetic field exposures from mobile telephones than a dults, but no epidemiological studies of ...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2006-2011

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

True exposure, measurement error and risk estimation in clinical and epidemiologic research

In epidemiology as well as in clinical studies our main interest lies in the estimation of the effect of exposure on disease. Most exposure data are subject to measurement error, and when ignored, they will bias our estimates of exposure-disease associati ons. It is important to understand the si...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2006-2009

Sted: Oslo

IS-BILAT-Mobilitet Norge-USA /Canada

Effect of SNPs in genes related to DNA stability and metabolism of fish and meat related mutagens on colorectal cancer risk

I propose to take advantage of an unique ongoing study to explore how polymorphisms in low penetrance metabolic and DNA repair genes may modulate diet-cancer associations. The study is carried out in USA and deals with colorectal cancer (CRC) in relation to fish- and meat related mutagens exposur...

Tildelt: kr 0,14 mill.

Prosjektperiode: 2006-2006

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Do socio-economic community factors affect mortality in Norway? An analysis based on unique multilevel longitudinal data.

The intention is to find out whether community characteristics exert an effect on an adult person's cause-specific mortality, above and beyond that of the person's individual characteristics. The focus will be on socio-economic community factors, such as average income and education and unemploym...

Tildelt: kr 0,90 mill.

Prosjektperiode: 2006-2008

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Hormone replacement therapy, gene expression profile and breast cancer

The project is mainly a collaboration between the University of Tromsø and INSERM, France. We will pool together information from the E3N cohort of about 100 000 French female teachers with the 150 000 participants in the Norwegian Women and Cancer study , NOWAC, both started in the early nineti...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2006-2008

Sted: Troms - Romsa - Tromssa

AS-HEL-Samfunnsmedisin og helsetj.

Statistical methods for investigating disease candidate genes: SNP haplotype association analyses, with orofacial clefts as a case study

Background: Over the last few years the availability and use of densely spaced SNPs (Single Nucleotide Polymorphisms) in genetic mapping and association studies has exploded. The candidate genes suggested by full genome scans or by functional studies need to be tested in separate epidemiological...

Tildelt: kr 0,11 mill.

Prosjektperiode: 2005-2006

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Norwegian Epidemiological Osteoporosis Studies. Why does the risk of osteoporotic fractures vary within Norway?

Norway has the world’s highest incidence of osteoporotic fractures. This large public health problem has severe consequences for the individual and for society. Bone mineral density (BMD) is the most widely used measure of bone strength. In spite of larg e regional differences in fracture risk, ...

Tildelt: kr 2,2 mill.

Prosjektperiode: 2005-2008

Sted: Vestland

PSYKISK-Psykisk helse

Long-term study #4 of the Norwegian survivors from the capsized oil rig in the North Sea, The "Alexander L Kielland"-Disaster

This will be the fourth study of the Norwegian survivors from the “Alexander L Kielland”-disaster. The study will draw data from prior studies with regards to disaster exposure, psychiatric symptoms, personality and childhood as well as health insurance d ata. Participants are survivors from th...

Tildelt: kr 1,7 mill.

Prosjektperiode: 2005-2012

Sted: Trøndelag - Trööndelage

MILGENHEL-Miljø, gener og helse

Air pollution, pregnancy outcomes and complications in Oslo 1992-2002

There is increasing evidence that current levels of urban air pollution can cause adverse health effects in humans. So far, the scientific documentation of fetal effects of urban air pollution is limited. However, the research question if ambient air poll ution can increase the risk of perinatal ...

Tildelt: kr 1,9 mill.

Prosjektperiode: 2005-2009

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Pregnancy, one-carbon metabolism and related single nucleotide polymorphisms

The proposed project is possible/feasible because of two parallel ongoing scientific activities in Norway: First, the Norwegian Mother and Child Cohort Study (NMCCS) is currently collecting information on life-style, diet, anthropometric measures and bloo d samples and have recruited about 38,000...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2005-2010

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

Caesarean delivery; indications and consequences

In Norway the occurrence of caesarean section (CS) has increased from 1.8% in 1967 to 15.7% in 2002, when almost 9000 CSs were performed. The increase may be attributed to changing indications for CS, a changing panorama of implications during delivery, a nd changing attitudes among women. A CS i...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2005-2008

Sted: Vestland

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