0 antall prosjekter

Dato fra ny til gammel

NEVRONOR-Nasjonal satsing på nevrovitenskap f

The Autism Database

The prevalence of autism spectrum disorders (ASD) has increased approximately 10-fold over the past 20 years, now affecting about 60 pr 10 000 children. ASDs are highly heritable neurodevelopmental disorders, with environmental factors possibly functioni ng as triggers in genetically susceptible...

Tildelt: kr 1,00 mill.

Prosjektperiode: 2008-2013

Sted: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Prediction of fetal growth restriction by maternal perception of fetal activity

Fetal growth restriction (FRG) is a major challenge in obstetric care, and a significant risk for severe disabilities and death. Risk is reduced by early detection, but prediction in antenatal care is poor. FGR is associated with decreased fetal movements (DFM). Pregnant women universally perfor...

Tildelt: kr 4,6 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Night work, circadian gene polymorphisms and breast cancer risk among female nurses. A nested case-control study

Less than half of all breast cancers can be explained by known risk factors. Results from recent epidemiological studies have been largely consistent in suggesting a positive association between night work and increased risk of breast cancer in women. Th ese findings suggest a role of circadian ...

Tildelt: kr 3,2 mill.

Prosjektperiode: 2008-2011

Sted: Oslo

FRIMEDBIO-Fri prosjektstøtte for medisin, helse og biologi

Folate, Paternal Age and De Novo Genetic and Epigenetic Events.

De novo mutasjoner er endringer i arvematerialet (DNA) som oppstår i kjønnscellene eller tidlig i fosterutviklingen og som derfor er nye i den forstand at de ikke finnes hos foreldrene. Epigenetiske mekanismer er kjemiske endringer i arvematerialet som styrer hvorvidt et gen skrus av eller på, op...

Tildelt: kr 4,5 mill.

Prosjektperiode: 2008-2015

Sted: Oslo

MILPAAHEL-Miljøpåvirkning og helse

Type 1 Diabetes and the Hygiene Hypothesis (helminths and parasites, and symptomatic virus infections)

Type 1 Diabetes (T1D) is one of the most prevalent chronic diseases with childhood onset. The incidence of T1D has increased with 25% during the last three years, and threefold during the last generation. The disease has a multifactorial aetiology and app ears after a long period where the immune...

Tildelt: kr 3,0 mill.

Prosjektperiode: 2008-2011

Sted: Oslo

RUSMIDDEL-Rusmiddelforskning

A biomarker-based tool to monitor community drug use and abuse in Norway: Monitoring of substances of abuse in wastewater effluents

An estimate of the Norwegian situation for addictive drugs is based mainly on the following input: - Death and disease associated with the use of drugs - Crime associated with drugs (e.g. number of seizures of different drugs, amount of confiscated drugs and blood samples from drivers suspected f...

Tildelt: kr 4,3 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

RUSMIDDEL-Rusmiddelforskning

Pathways and consequences of alcohol, cannabis and prescription drug involvement. A longitudinal 13-year follow up of a population sample.

This research project has three main research questions. (1) What is the importance of alcohol and drug use debut age for later development of drug problems? (2) What are the risk factors for later cannabis use and what are the consequences of this use? ( 3) What are the risk factors for later us...

Tildelt: kr 3,5 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

IS-BILAT-Mobilitet Norge-USA /Canada

Maternal Corticotropin-releasing hormone levels during pregnancy and offspring levels of Adiponectin

Obesity and it's consequences are emerging as a prime threat to health in the western world. During the last 20 years the prevalence of obesity has increased in all age groups, including children. This has led the search for etiological clues. Several st udies have shown an association between l...

Tildelt: kr 33 000

Prosjektperiode: 2008-2008

Sted: Trøndelag - Trööndelage

PSYKISK-Psykisk helse

Preschool ADHD: Early characteristics, developmental trajectories, risk and protective factors in a prospective birth cohort

Background: ADHD is highly prevalent, characterized by age inappropriate levels of inattention, hyperactivity and impulsiveness. It represents a substantial threat to healthy social and academic development, and increased risk for psychiatric comorbidity. Knowledge about early characteristics, d...

Tildelt: kr 4,3 mill.

Prosjektperiode: 2008-2015

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Diabetes and diabetes precursors: detection, classification, prediction, genetics, complications and prevention. The Tromsö Study.

The incidence and prevalence of diabetes mellitus are increasing in many populations, and diabetes is now one of the most prevalent chronic diseases worldwide. Diabetes carries a great disease burden in terms of morbidity, mortality and costs. Most cases are classified as Type 2 diabetes, which h...

Tildelt: kr 3,0 mill.

Prosjektperiode: 2008-2011

Sted: Troms - Romsa - Tromssa

RUSMIDDEL-Rusmiddelforskning

Pilot study: prevalence of alcohol and drugs at the workplace

Alcohol and drug abuse affects society in many ways, e.g., health, social relations, safety, and productivity at the workplace. Alcohol is more significant in this respect than drugs because the use of alcohol is common and accepted by society. Testing of oral fluid (saliva) may be used to dete...

Tildelt: kr 1,00 mill.

Prosjektperiode: 2008-2009

Sted: Oslo

MILPAAHEL-Miljøpåvirkning og helse

Hearing loss and tinnitus: genetic and environmental effects

Depending on the criteria used 1/3 - 1/6 of the population experience hearing impairment. Tinnitus is defined as the sensation of sound without any outer sound stimulus present. Environmental risk factors such as noise exposure are frequently described fo r both the diseases. A genetic component ...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2008-2015

Sted: Oslo

PSYKISK-Psykisk helse

Folate and fatty acids in early life and neurodevelopmental disorders: developmental language delay as an early marker

We intend to study the relationship between intake of folate and fatty acids during early life and the risk of neurodevelopmental disorders (ND) such as autism and attention deficit/ hyperactivity disorder (ADHD). Having language problems at the age of three is a strong predictor for neurodevel...

Tildelt: kr 5,2 mill.

Prosjektperiode: 2007-2013

Sted: Oslo

FOLKEHELSE-Folkehelse

Physical activity and chronic pain in HUNT 3 - A prospective cohort study

Regular physical activity promotes health. An inactive lifestyle may alter gene expression, influence negatively on several organ systems and thereby cause chronic disease and increase mortality. These conditions may be reversed by regular activity and in creased level of physical fitness. Physic...

Tildelt: kr 5,0 mill.

Prosjektperiode: 2007-2011

Sted: Trøndelag - Trööndelage

FRIMED-Klinisk medisin og folkehelse

Statistical modelling for infectious disease

We want to build a viable research group in statistical and mathematical modelling of infectious disease. We wish to make important original contributions to statistical methodology for analysis on infectious disease data, for the further purpose of aidin g, monitoring and understanding the sprea...

Tildelt: kr 2,8 mill.

Prosjektperiode: 2007-2011

Sted: Oslo

FOLKEHELSE-Folkehelse

Past and current physical activity levels and the risk of fracture in a population based study with 25 years follow-up

Norway has the highest fracture incidence in the world, and data from Oslo indicate increasing incidence in both sexes to the end of 1990. Physical activity stimulate bone formation during growth and maintain bone strength and reduce bone loss in adulthoo d and old age. Physical activity througho...

Tildelt: kr 3,6 mill.

Prosjektperiode: 2007-2011

Sted: Troms - Romsa - Tromssa

MILGENHEL-Miljø, gener og helse

Cardiovascular morbidity and mortality: Effects of noise or air pollution or both?

Since road traffic is a source of both air pollutants and noise, it is very important to disentangle the health effects of the two very different types of environmental exposures related to road traffic. There are indications that both noise and air pollu tion are associated with increased risk o...

Tildelt: kr 2,9 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Pregnancies and cancer risk - a prospective study based on Norwegian register data

In this project, associations between pregnancies and cancer risk will be examined. Focus will be on cancer forms known to be hormone-related, and also on some cancer types with less evidence for being susceptible to hormonal exposure. Our study is based on information from the Population registe...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2007-2010

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

Psychosocial effects and understanding of increased risk for Type 1 Diabetes

With the rapid development in biotechnology and increasing knowledge about the relation between diseases and genetic variability, we are faced with both new opportunities and new dilemmas. Onset of a disease is dependent on several factors as genetic pene trance, combinations of genotypes and env...

Tildelt: kr 2,8 mill.

Prosjektperiode: 2007-2010

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

Retinopathy and AMD in a general population. The Tromsø Study 2007.

The Tromsø VI survey is scheduled to take place October 2007- through 2008. A total of 11,000 - 16,000 adults in Tromsø will be invited (depending on funding). Many of those have participated in previous surveys, and data from those surveys will be used f or longitudinal analyses. As a subproject...

Tildelt: kr 1,4 mill.

Prosjektperiode: 2007-2010

Sted: Troms - Romsa - Tromssa

FRIMED-Klinisk medisin og folkehelse

Gene-environment interaction analyses and oral clefts in Norway

Norway has several large epidemiological studies with genetic bio-banks that may be used in etiologic research. Examples are the CONOR-cohort and the MoBa-cohort of children with mothers and fathers. Optimal analysis of such studies requires integration o f both genetic and environmental effects....

Tildelt: kr 2,8 mill.

Prosjektperiode: 2007-2011

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

THE HORDALAND WOMEN'S COHORT STUDY. A planned 15-year (1997-2012) follow up incidence study of urinary incontinence, and associated factors

Urinary incontinence (UI) is a common condition with a prevalence of about 25% of adult women, that affects the physical, psychosocial, and economic well-being. Longitudinal studies of incidence, remission and natural history are scarce. The Hordaland wo men's cohort study is an ongoing 15-year ...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2007-2011

Sted: Vestland

FRIMED-Klinisk medisin og folkehelse

Exposure expression profiles in a prospective cancer study - The Norwegian Women and Cancer postgenome cohort

From 1991 women in Norway has been recruited to participate in NOWAC by postal questionnaires. They are drawn at random from the population through the central person register. Follow-up on cancer and death is based on linkage to national registers. Altog ether 150 000 women aged 30-70 years at r...

Tildelt: kr 1,6 mill.

Prosjektperiode: 2007-2010

Sted: Troms - Romsa - Tromssa

FOLKEHELSE-Folkehelse

Is osteoporosis related to the risk of atherosclerosis and cardiovascular disease?

Cardiovascular disease (CVD) and osteoporosis are major causes of morbidity and mortality among elderly people. The two conditions have generally been considered unrelated. However, studies have indicated that arterial calcification is an active, organise d, regulated process similar to bone mine...

Tildelt: kr 2,5 mill.

Prosjektperiode: 2006-2009

Sted: Troms - Romsa - Tromssa

MILGENHEL-Miljø, gener og helse

Food from the sea - health effects of organic pollutants and essential nutrients from marine food. The Norwegian Women and Cancer Study.

In the Norwegian Women and Cancer study (NOWAC), detailed dietary information is available in addition to a large biobank. Altogether 68 000 women aged 41-70 years at recruitment have been followed up for cancer incidence and mortality through linkages to national registers based on the unique n...

Tildelt: kr 2,7 mill.

Prosjektperiode: 2006-2009

Sted: Troms - Romsa - Tromssa

FOLKEHELSE-Folkehelse

The Hordaland Homocysteine and Health Studies - biobanks and follow-up studies

This is a joint application to cover staff (0.5 position) for project and data management, statistical and laboratory services plus running project expences for the Hordaland Homocysteine Study and the Hordaland Health Study. The Norwegian Research Counci l has previously provided such support an...

Tildelt: kr 2,0 mill.

Prosjektperiode: 2006-2009

Sted: Vestland

FOLKEHELSE-Folkehelse

The epidemiology of prescription drug use. A record-linkage study in Norway

Three surveys will form the basis of this project: a) The Cardiovascular Survey Progamme in Norway 1972-2004, b) The Youth part of a) 2000-2004, c) Norwegian Epidemiological Osteoporosis Studies (NOREPOS) 1994-2001. The information in these databases wil l be supplemented with information on soc...

Tildelt: kr 4,4 mill.

Prosjektperiode: 2006-2010

Sted: Oslo

MILPAAHEL-Miljøpåvirkning og helse

The Nordic-Swiss Childhood Brain Tumour Study

During the last decade, the use of mobile telephones has increased dramatically in large parts of the world. It has been hypothesized, that children should be more vulnerable to radio frequency electromagnetic field exposures from mobile telephones than a dults, but no epidemiological studies of ...

Tildelt: kr 1,8 mill.

Prosjektperiode: 2006-2011

Sted: Oslo

FRIMED-Klinisk medisin og folkehelse

True exposure, measurement error and risk estimation in clinical and epidemiologic research

In epidemiology as well as in clinical studies our main interest lies in the estimation of the effect of exposure on disease. Most exposure data are subject to measurement error, and when ignored, they will bias our estimates of exposure-disease associati ons. It is important to understand the si...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2006-2009

Sted: Oslo

IS-BILAT-Mobilitet Norge-USA /Canada

Effect of SNPs in genes related to DNA stability and metabolism of fish and meat related mutagens on colorectal cancer risk

I propose to take advantage of an unique ongoing study to explore how polymorphisms in low penetrance metabolic and DNA repair genes may modulate diet-cancer associations. The study is carried out in USA and deals with colorectal cancer (CRC) in relation to fish- and meat related mutagens exposur...

Tildelt: kr 0,14 mill.

Prosjektperiode: 2006-2006

Sted: Oslo

1 2 3 4 5 6 7