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BIOTEK2021-Bioteknologi for verdiskaping

eXploring the BIOactive PEPtide Space of arctic marine invertebrates

Målsetningen med prosjektet har vært å karakterisere og avdekke nye bioaktive peptider fra marine dyr/evertebrater fra Arktiske og sub-Arktiske områder og få kunnskap om struktur (gener) og virkemåter. Videre ønsket vi å utnytte denne kunnskapen i utvikling av lead forbindelser som kan anvendes i...

Tildelt: kr 7,0 mill.

Prosjektperiode: 2011-2017

Sted: Troms - Romsa - Tromssa

BIOTEK2021-Bioteknologi for verdiskaping

Development of technology for flow cytometry- and other cell-based, high-content, high-throughput analyses to support marine bioprospecting

ChemBioNet Norway - Norwegian Chemical Biology Platforms is a national network of HTS screening platforms (part of ESFRI-project EU-Openscreen) that support marine bioprospecting and drug screening. A joint application to the Infrastructure Programme for investments to support marine bioprospect...

Tildelt: kr 4,0 mill.

Prosjektperiode: 2011-2015

Sted: Oslo

BIOTEK2021-Bioteknologi for verdiskaping

Collaboration initiatives towards the developments of natural plant and marine based products for medical and biotechnological use

For thousand of years, humans have used plants to treat diseases, even though the active content of such plants materials were not known neither the mechanism of actions of such compounds. Indeed, many of such compounds from plant origin are still in clin ical practice today. The identification o...

Tildelt: kr 0,50 mill.

Prosjektperiode: 2011-2014

Sted: Troms - Romsa - Tromssa

BIOTEK2021-Bioteknologi for verdiskaping

Exploring Legal Conditions and Framework for Marine-based Bioprospecting and Innovation

Marin bioprospektering innebærer å lete etter og samle inn gener, biomolekyler og organismer fra det marine miljø. Dette kan være bakterier, alger og dyr som lever på havbunnen eller i vannsøylen og som har tilpasset seg de ekstreme forhold som finnes der. Det er store forventinger til at marin b...

Tildelt: kr 5,3 mill.

Prosjektperiode: 2011-2016

Sted: Akershus

BIOTEK2021-Bioteknologi for verdiskaping

Mining of a Norwegian biogoldmine through metagenomics

Varme kilder i dyphavet langs den Arktiske Midt-Atlantiske Spredningsryggen kan karakteriseres som noen av de mest ekstreme habitat funnet på norsk sektor. I dyp helt ned til 2400 meter under havoverflaten har vi oppdaget oaser av liv som livnærer seg på reduserte kjemiske forbindelser som følge ...

Tildelt: kr 5,4 mill.

Prosjektperiode: 2011-2015

Sted: Vestland

BIOTEK2021-Bioteknologi for verdiskaping

Establishment of a bioprospecting network: Searching for novel anti-cancer agents in plants and microorganisms.

The project will gather experts in the field of natural products chemistry, microbiology and bioactive compounds, cell and tumour biology to make a bioprospecting cluster. This cluster will work to shorten the translational pipeline from discovery of a bi oactivity to clinical trials. The main pa...

Tildelt: kr 0,23 mill.

Prosjektperiode: 2011-2013

Sted: Vestland

BIOTEK2021-Bioteknologi for verdiskaping

Purified heparin from marine raw materials

Hepmarin AS has developed and patented processes to produce Heparin, using marine species as raw material. These are more efficient and cheaper than existing technology, solves contamination issues through the use of a traceable raw material source, and w ill not have the ethical/religious issues...

Tildelt: kr 1,2 mill.

Prosjektperiode: 2011-2012

Sted: Oslo

BIOTEK2021-Bioteknologi for verdiskaping

Cell-based screening for small membrane permeable metal chelators of marine origin

Several human diseases involve iron dyshomeostasis, and metal accumulation of iron, copper, cadmium, mercury and lead in human organs affect our well-being, cause cancer and accelerate ageing of organs. Low-toxic compounds capable of removing potentially toxic metals from cells and tissue are th...

Tildelt: kr 5,4 mill.

Prosjektperiode: 2011-2017

Sted: Troms - Romsa - Tromssa

FUGE-Funksjonell genomforskn.i Norg

Malaria control in Africa using plant extracts - Project establishment support

In the current pilot project phase we want to establish an international interdisciplinary research group to develop a proposal for a 3-year main project with the aim of developing locally based phytomedicines and insecticides to control malaria in Africa . The research group consists of scientis...

Tildelt: kr 0,50 mill.

Prosjektperiode: 2011-2011

Sted: Akershus

FUGE-Funksjonell genomforskn.i Norg

System biology of microorganisms: Enterococcus faecalis and Lactobacillus plantarum

SysMO-LAB2 aims to extend and further develop comparative systems biology approaches to understand similarities and differences in fermentation behaviour of four Lactic Acid Bacteria (LAB). Lactococcus lactis, used in dairy food applications; Enterococcus faecalis, a major (fecal) contaminant in...

Tildelt: kr 5,5 mill.

Prosjektperiode: 2010-2014

Sted: Akershus

FUGE-Funksjonell genomforskn.i Norg

Application for support of the annual contact meeting of the Norwegian Biochemical Society.

...

Tildelt: kr 0,36 mill.

Prosjektperiode: 2010-2012

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

Synthetic and Systems Biology at SynBERC (USA): new ideas and possibilities for collaboration on genome-based bioprospecting

Initial mining of genomes of several bacteria isolated from the Trondheim fjord revealed great biotechnological potential of these microorganisms in terms of production of small molecules and enzymes. Preliminary data strongly suggest that only a very sma ll portion of this potential is realized ...

Tildelt: kr 31 999

Prosjektperiode: 2010-2010

Sted: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

Reflexive Systems Biology: towards an Appreciation of Biological, Scientific and Ethical Complexity

The ambitions of systems biology and synthetic biology are often stated in terms of prediction, control, design and fabrication of organisms. If possible, the ethical and social aspects involved may be huge, including those of biosafety and biosecurity. W e propose an advanced project combining S...

Tildelt: kr 4,9 mill.

Prosjektperiode: 2009-2014

Sted: Vestland

FUGE-Funksjonell genomforskn.i Norg

Identification of boar semen gender specific proteins and peptides

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Tildelt: kr 2,1 mill.

Prosjektperiode: 2009-2012

Sted: Rogaland

FUGE-Funksjonell genomforskn.i Norg

Genome sequencing of cod by exclusive use of ultra-high-throughput sequencing technology

We propose a project characterized by exclusive use of new ultra-high-throughput sequencing technology combined with state-of-the art bioinformatics algorithms designed for maximal exploitation of this technology. The project will be carried out in close collaboration with 454 Life Sciences, the...

Tildelt: kr 10,0 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

Identification of key antiviral and inflammatory modulators in Atlantic cod (Gadus morhua L.)

Atlantic cod has recently been introduced into aquaculture in Norway and is expected to constitute a major part of Norwegian fish farming within few years. Expansion of this industry faces many challenges, including disease problems. From farming of salmo nids we know that vaccination has been a ...

Tildelt: kr 5,3 mill.

Prosjektperiode: 2008-2011

Sted: Troms - Romsa - Tromssa

FUGE-Funksjonell genomforskn.i Norg

Information material for public health care professionals

We would like to produce information material for physicians, midwives and other health care workers who meet the couples before, during and after their pregnancy. We would like to make information folders and also write in journals read by the health car e professionals. We would also like to ma...

Tildelt: kr 0,15 mill.

Prosjektperiode: 2008-2010

Sted: Vestland

FUGE-Funksjonell genomforskn.i Norg

An integrative genomics approach to identify genes and biochemical pathways underlying complex traits in Atlantic salmon

Identifying the genes and biochemical pathways in salmon that are responsible for economically important traits is the primary focus of this application. While a wealth of phenotypic data is available (e.g. the salmon biobank) the ability to resolve causa tive genes and loci has been technology l...

Tildelt: kr 5,0 mill.

Prosjektperiode: 2008-2012

Sted: Akershus

FUGE-Funksjonell genomforskn.i Norg

Tissue Factor siRNA for treatment of melanoma metastasis

The project described herein covers the research and initial preclinical part of the project of developing a drug based on small interfering RNAs (siRNA) targeting Tissue Factor, a molecule known to be involved in the processes of blood clotting, metastas is and angiogenesis. The project has emph...

Tildelt: kr 1,9 mill.

Prosjektperiode: 2008-2011

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

Bioinformatics platform for the pharmacogenomic analysis of sequence variation in complex diseases

Traditional studies of complex disease and drug response have utilized a one gene one drug strategy. However because of highthroughput technology , the future trend of personalized medicine lies in understanding and modulating the complex responses involv ing many genes, their sequence variation ...

Tildelt: kr 3,5 mill.

Prosjektperiode: 2008-2011

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

The Norwegian plant transcriptional profiling centre

The Norwegian Arabidopsis Centre (FUGE-NARC) was established as a part of FUGE I. NARC provided national service in plant functional genomics and the service activity was shared between Univeristy of Life Sciences (UMB, transformation/genotyping), Univers ity of Oslo (Y2H, in situ hyb) and Norwe...

Tildelt: kr 2,3 mill.

Prosjektperiode: 2008-2013

Sted: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

The Proteomics Core Facility at the University of Tromsø as a node in the national consortium of proteomics platforms (NorProteomics)

The core facility for Proteomics in Tromsø has been fully operational since the end of 2004. The main purpose of the facility has been to serve research labs in the FUGE North region. The facility has 3 Mass spectrometer systems from Waters/Micromass. A M ALDI Micro MX, a Q-TOF Ultima Global with...

Tildelt: kr 1,3 mill.

Prosjektperiode: 2008-2012

Sted: Troms - Romsa - Tromssa

FUGE-Funksjonell genomforskn.i Norg

Advanced MR imaging, MR metabolomics, proteomics and genetic mapping of breast cancer - Clinical tools for personalized patient treatment

Breast cancer has the highest incidence and mortality of all malignant diseases among women globally. The heterogeneous nature of breast cancer results in different clinical presentations and outcomes, and patients show a diverse range of responses to a g iven treatment. Processes leading to more...

Tildelt: kr 5,2 mill.

Prosjektperiode: 2008-2011

Sted: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

A node of the FUGE platform for proteomics at the Biotechnology Centre of Oslo

Specialized proteomics service will be provided by the node at the Biotechnology Centre of Oslo for i.) quantitative proteomics ii.) clinical proteomics, and iii.) cell death proteomics. Quantitative proteomics will be performed either in cell culture by stable isotopic labeling of amino acids du...

Tildelt: kr 2,2 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

Postgenome glycomics: The structures, interactions, and functions of complex sugars attached to proteins and lipids

Glycome is a term meant to cover the whole set of glycans produced in a single organism (or tissue) in analogy to genome and proteome. This concept follows as a consequence of the development in the post-genome era, since glycans play critical roles in di verse biological phenomena. It seems evid...

Tildelt: kr 8,0 mill.

Prosjektperiode: 2008-2011

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

Salmon louse genome sequencing and functional studies on host parasite interactions

Copepods comprise the largest animal marine biomass but they have been poorly studied by molecular tools and no genome has so far been sequenced. Copepods are common as parasites on fishes and the salmon louse (Lepeophtheirus salmonis) is the most importa nt species in terms of economical signifi...

Tildelt: kr 6,0 mill.

Prosjektperiode: 2008-2011

Sted: Vestland

FUGE-Funksjonell genomforskn.i Norg

National-wide service and competence from the Rikshospitalet-Radiumhospitalet Proteomics Core Facility in a Norwegian proteomics consortium

The Proteomics Core Facility at Rikshospitalet-Radiumhospitalet (RR-PCF) is a core facility platform organized jointly by Rikshospitalet-Radiumhospitalet HF (RR) and the University of Oslo (UiO) through "Felles Forskningsutvalg" at the hospital. The RR-PC F is engaged in the development of proteo...

Tildelt: kr 1,5 mill.

Prosjektperiode: 2008-2012

Sted: Oslo

FUGE-Funksjonell genomforskn.i Norg

Norwegian Molecular Imaging Consortium - Bergen

The present-day Molecular Imaging Center in Bergen (MIC) is an open facility that offers a collection of state-of-the-art microscopy equipment and image processing tools. MIC initiated its services in 2003 and was set up as a cooperation between NTNU in T rondheim and the University of Bergen to ...

Tildelt: kr 9,2 mill.

Prosjektperiode: 2008-2012

Sted: Vestland

FUGE-Funksjonell genomforskn.i Norg

A National Service Platform for Global Analysis of Genome Structure and Function. The Norwegian Microarray Consortium (NMC)

The FUGE Microarray Platform is run by the Norwegian Microarray Consortium (NMC), based on a formal institutional collaboration between RR/UiO, NTNU, and UiB. We offer in-house production of standard and custom arrays, expression and genomic profiling ser vices (RNA or DNA in-DATA out) with diffe...

Tildelt: kr 9,7 mill.

Prosjektperiode: 2008-2013

Sted: Trøndelag - Trööndelage

FUGE-Funksjonell genomforskn.i Norg

Bacterial flagellin: a novel adjuvant for vaccine strategies

The focus will be on development of strongly protective vaccines aimed primarily to fish, but the knowledge generated will be highly relevant within vaccine development to mammalian species - as fish possess very similar immune defence mechanisms compared to mammalian species. This will be achie...

Tildelt: kr 5,3 mill.

Prosjektperiode: 2007-2011

Sted: Troms - Romsa - Tromssa

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