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KOSK-Katalyse og organisk syntetisk kjemi

Modified carbohydrates from 3,3,4,4-tetraethoxy-1-butyne

Tildelt: kr 1,8 mill.

The purpose of this project is to explore the functionalisation of different alkenols (produced by coupling of 3,3,4,4-tetraethoxy-1-butyne with aldehydes and ketones and subsequent reduction), at the carbon-carbon double bond with the aim of obtaining ca rbohydrate derivatives, which are modified at C-3 or C-4 or at both. The project will focus on the introduction of amino and perfluoroalkyne groups at these positions, to give amino-sugar and perfluoroalkyl-sugar derivatives. Amino-sugar derivatives play an important role in the human immune system and are often found as substructures in natural products. Perfluoroalkyl-substituted sugar derivatives have properties which indicate that they should be useful as surfactants and e mulsifiers for biomedical applications.

Budsjettformål:

KOSK-Katalyse og organisk syntetisk kjemi

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