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FUGE-Funksjonell genomforskn.i Norg

Functional genomics studied by modern mass spectrometry

Tildelt: kr 7,4 mill.




2004 - 2009



The human genome in itself does not explain the intricate molecular details of human cells and the origins of human diseases. The observed amazing complexity is rather realized via dynamical alterations of the gene products, the proteins. Proteomics research in cell biology and biomedicine in the post-genome era focuses on the identification and detailed characterization of large sets of expressed proteins to elucidate protein function and dynamics. Mass spectrometry has developed as a key technology in that functional genomics endeavor. Burkhard Fleckenstein (BF), Institute of Immunology/UiO, applies for a career stipend to study functional genomics by means of modern mass spectrometry and proteomics. His ambition is to bring in his expertise to build up an own research group performing cutting edge science in protein/peptide analysis at the Gaustad campus (Rikshospitalet) in Oslo. BF is an expert in mass spectrometry. He was trained as a guest researcher in Prof Roepstorff’s laboratory in Odense/Denmark, who is heading one of the world’s leading groups in that field. This strong collaboration to Prof Roepstorff will continue. BF has an “open door” to the inspiring environment in Denmark, and Prof Roepstorff will follow the setup of the laboratory in Oslo with his invaluable advice. During his work BF will strongly interact with experimental biologists and clinicians on a local, national and international level.


FUGE-Funksjonell genomforskn.i Norg