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TU-Tungt utstyr

Application for Advanced Scientific Equipment: HTS Bioimaging

Tildelt: kr 2,0 mill.

RATIONALE FOR EQUIPMENT INVESTMENT The ability to study gene function on a large scale and systematically rather than one-by-one or case-by-case is the essence of functional genomics. A major criticism of the FUGE 1 program by the international Evaluatio n Panel was the lack of truly high throughput functional genomic projects in Norway. In the case of the Molecular Imaging Center, the lack of dedicated infrastructure and local scientific projects targeting high throughput screening compromised this devel opment. "The most important recommendation is that MIC implements high throughput technologies in Bergen..." p82. FUGE Evaluation Report, FUGE Board, NFR (2006) Following the major recommendations of the FUGE Evaluation Panel, the MIC platform endeavors in FUGE II to build expertise in high throughput/high content imaging (HTS bioimaging). Through local projects and international collaborators, MIC/Bergen has the opportunity to establish HTS bioimaging as an integral part of the platform. To achieve th is, MIC/Bergen requires an investment into advanced equipment dedicated to HTS bioimaging technology. The equipment will be maintained by current MIC/Bergen staff in collaboration with dedicated local investigators and international experts. During the in itial phase of the program, HTS bioimaging technology will be established via local collaborating scientific groups (Lorens, Gerdes, Lundervold) and international experts (Pepperkok, Link, Rines, McLaughlin). In a second phase, MIC will make this technolo gy available to the general scientific community of Norway.

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