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MAMMOGRAFI-Evaluering av Mammografiprogr

Overdiagnosis in the Mammography Breast Cancer Screening Programme in Norway

Tildelt: kr 0,73 mill.

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We plan to retreive data from Norwegian agencies on breast cancer incidence by region, age group and calendar period, along with data on screening exposure by the same factors. In addition, we plan to obtain individual screening data, including numbers sc reened, cancers detected, interval cancers, and tumours diaognised in non-attenders. We shall estimate the effect of screening on long-term cumulative incidence of disease, including at least ten years after the upper age limit for screening. An excess in cumulative incidence still observed years after stopping screening can reasonably be attributed to overdiagnosis. We shall also estimate overdiagnosis explicitly from multistate disease progression models. For this we shall use both conventional statis tical estimation and inference, and microsimulation techniques.

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MAMMOGRAFI-Evaluering av Mammografiprogr

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