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FRINATEK-Fri prosj.st. mat.,naturv.,tek

Responsive (bio)polymer matrices as Fabry-Perot cavities: A versatile platform for development of nanostructured (bio)polymer materials

Tildelt: kr 6,0 mill.

The project focuses on determination of high resolution swelling data of responsive, soft (bio)polymer materials by the application of an optical interferometric technique with nanometer precision in changes of the optical length of the soft materials. Ba sically, the responsive hydrogel materials will be integrated at the end of an optical fiber and the light sent through the fiber reflected at the fiber-soft material, and soft-material-surronding interfaces interfere and will be used for the analyses of the optical pathlength in the hydrogel. The reflected interference wave thus formed is the basis for the high resolution determination of the soft material making up the Fabry-Perot cavity. The materials characterization will be performed on developed bio functionalized polymer matrices suitable for continuous label-free biosensor applications, on (bio)polymer coated polymer cores for the high precision mechanical characterization of the (bio)polymer film when developing a barrier functionalities for livin g cell immobilization materials, and for the functional hydrogel response associated with drug delivery. The development of a functionalized hydrogels suitable for biospecific label-free detection focuses on biological macromolecules suitable for high sen sitive detection of DNA sequences, which is suitable for a number of potential applications. The fundamental technology platform described underpin development of bio-functionalized hydrogels as high resolution sensor materials, and control of barrier sel ectivity by nanostructured (bio)polymer interfaces.

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FRINATEK-Fri prosj.st. mat.,naturv.,tek