Optisk ikke-invasiv vevsdiagnose

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A novel diagnostic imaging concept [Optical Transfer Diagnosis (OTD)] is being developed for non-invasive diagnosis of skin cancer, and is in the process of being commercialized. The OTD technolgy is based on illuminating a selected area of tissue from se veral directions with light of several wavelengths and detecting the reflected light in several observation directions. The goal of this R&D project is to further develop the OTD technology for diagnosis of cancer or other serious illnesses on tissue surf aces inside the human body. The R&D effort encompasses development of forward models for calculation of reflected light from the tissue when the illumination and the optical properties of the tissue are known, development of bio-optical models that descri bes the connection between optical properties and relevant physiological and morphological parameters, development of tissue specific inverse methods for determining the optical properties of the tissue and thereby also the relevant physiologigal and morp hological parameters from measurements of the reflected light, development of diagnostic tools based on correlation between pathological results from biopsies and diagnostic results determined by the OTD technology, and clinical investigations, including biopsies to test and avaluate the OTD technology in practical use.