Life Sciences and Nano Sciences interact in two areas: in the evaluation of health and environmental effects derived from engineered nanomaterials, and in development and biological/clinical evaluation of nanoparticles with intended biological effects for application in medicine and biotechnology. It is essential that the safety of products containing nanomaterials can be certified with reliable, validated assays. Research efforts are under way to establish suitable test methods and to understand mechanis ms potentially leading to a detrimental impact of nanomaterials on human health and on the environment. However, this important field still urgently lacks sufficient trained personnel. The ITN 'Nanotechnology: Training Of Experts in Safety' (NanoTOES) wil l establish a network of research projects working towards the refinement and standardisation of existing methods, will develop novel assays, and will during this process provide interdisciplinary training to Early Stage Researchers (ESR) and Experienced Researchers (ER) working at the intersection of biosciences and nanosciences. A suite of methods developed and validated in the NanoTOES project shall have utility in characterising the biological effects of nanomaterials, including their impact on the en vironment, and will add significantly to our understanding of the biological actions of nanomaterials and their resultant effects on human health and the environment. Equally, the influence of biological entities (molecules, cells, tissues) on the propert ies of nanomaterials will be investigated.
Within NanoTOES, PhD student Anna Huk will work on the sub-project 'Assessment of genotoxic potential of nanoparticles, oxidative DNA damage and repair'.
NanoTOES is running from 01.11.2010 to 31.10.2014, wher eas the named sub-project started 01.05.2011 and will end 30.04.2014.