Contaminant of emerging concern (CECs) such as antibiotics, pathogens and antimicrobial resistant (AMR) bacteria in water bodies associated to intensive ?sh and inland animal farming, represent a great threat to the environment and human health. AMROCE aims at reducing antibiotic pollution and spread of AMR bacteria in the entire water cycle through a platform of novel antibiotic-free antimicrobial products. AMROCE will develop antimicrobial/antibio?lm ?sh cage nets and wastewater ?ltration membranes through polymer bulk and surface nano-engineering. Marine-derived antimicrobial agents and antibio?lm enzymes will be nano-formulated as alternative to antibiotics for ?sh and animal feed supplement. Human and environmental nanosafety during the manufacturing and use of the novel nanotechnology-embedded products will be continuously evaluated to anticipate nanosafety issues.