FRIMEDBIO-Fri prosj.st. med.,helse,biol
B-cell lymphomagenesis in Ung-deficient mice: collaboration between chronic antigenic stimulation and DNA repair deficiency
The importance of responding appropriately to DNA damage is highlighted by the frequent development of human disease, most notably cancer, in cells where this response is compromised. Here, we ask whether endogenous DNA damage, such as uracil in DNA, can contribute to activation of the DNA damage...