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2014

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About Prosjektbanken

2004

Utdannings- og forsk

Matematikk og naturvitenskap

Vestland

UoH-sektor

Frittstående prosjekter

Ingen søknadstype

Limb wounds in horses are common, however healing is exceedingly slow and fraught with complications. Contrary to body wounds, limb wounds demonstrate only a small amount of wound contraction. The specialist procedure of applying split-thickness skin grafts to limb wounds stimulates wound contraction by unknown mechanisms. The objective of this project is to identify those mechanisms to develop a treatment strategy for equine limb wounds for use in general  practice. Limb wounds are severely impacting animal welfare due to an extended healing/treatment duration, and the risk of euthanasia due to a poor functional outcome. By stimulating wound contraction, healing time will be reduced, and the functional outcome improved, directly benefitting the welfare of wounded horse and reducing treatment cost for the owner. Aim: To identify dermal components stimulating wound contraction, and to develop this knowledge into future state-of-the-art treatment of equine limb wounds for use in general practice. Hypotheses: i) Application of dermal fractions to collagen gels seeded with equine fibroblasts will increase gel contraction in vitro; ii) Application of dermal fractions to experimental limb wounds in vivo, will increase wound contraction resulting in a faster healing time versus wounds treated by conventional methods. Methods: i) The contractile effect of different dermal components will be assessed in a collagen gel/ fibroblast model; ii) Identified dermal components will be tested in a standardized experimental limb wound model in vivo (n=5). Ultimately, results from this project are expected to improve wound treatment in horses, directly impacting animal welfare by reducing healing time and improving the functional outcome of wounded horses. This will also directly benefit horse owners and caretakers and making veterinarians able to offer better treatment solutions.

HESTEFORSK - Raskere og bedre sårheling hos hest med autologe hudkomponenter

Effektene av fysisk og seksuell vold på ofre og deres familier kan være ødeleggende og vedvarende, med potensielt langvarige konsekvenser for fysisk og mental helse, utdanning, sysselsetting og bruk av velferdstjenester. Mens strafferettssystemet anses som en viktig del av offerets gjenopprettingsprosess, er det begrenset empirisk forskning på hvorvidt strafferettslige prosesser hjelper og/eller hindrer bedring langs disse ulike dimensjonene. I dette prosjektet vil vi adressere dette kunnskapshullet ved å bruke en kombinasjon av kvantitative og kvalitative forskningsmetoder. I de kvantitative analysene vil vi bruke administrative registerdata som dekker hele befolkningen sammen med kvasi-eksperimentelle metoder for å kunne trekke kausale slutninger. Vi vil også benytte maskinlæringsteknikker for prediksjon. De kvalitative analysene vil supplere de kvantitative analysene ved å gi kontekst til et komplekst felt av saker og ofre og ved å identifisere potensielle mekanismer mellom strafferettslige prosesser og utfall for ofrene. Samlet vil disse metodene gi en mer robust, representativ og nyansert forståelse av hvordan kontakt med strafferettssystemet påvirker offeret på tvers av flere viktige livsområder både på kort og lang sikt. Prosjektet ledes av Folkehelseinstituttet (FHI) med Frischsenteret og Universitetet i Oslo som partnere. Prosjektet har et rådgivende utvalg med medlemmer fra Nasjonalt kunnskapssenter om vold og traumatisk stress (NKVTS), ETH Zurich, Universitetet i Oslo, Frischsenteret, Universitetet i Bergen, og OsloMet. Det er også tilknyttet en brukergruppe bestående av personer og organisasjoner som er i kontakt med ofre for vold og overgrep.

Victims of sexual and physical violence is one of the most vulnerable groups in our society. The criminal justice system (CJS) serves a critical role in providing assistance to victims of these crimes, enabling them to seek justice, protection, compensation, and closure. Yet, knowledge about whether the CJS helps or harms these victims is extremely limited. This project aims to remedy this by providing a comprehensive understanding of the role of the CJS in supporting and providing restoration for victims of physical and sexual violence in Norway. We will utilize a combination of quantitative and qualitative research methods across disciplines to study outcomes across multiple important life domains, both in the short and long run. For the quantitative analyses we will use exceptionally rich longitudinal administrative register data with full population coverage combined with state-of-the-art quasi-experimental methods for credible causal inference and predictive machine learning techniques. The qualitative analysis will be based on narrative interviews with victims, providing context and insights into how interactions with the CJS shape life stories. The results will yield a robust and nuanced understanding of how the different stages of the CJS impacts victims. This is particularly urgent given how the current emphasis on legal responses to assaults has caused a sense of obligation and civic duty for especially women to report incidents, while the chances of legal closure remain small. In addition to advancing the methods for quasi-experimental designs and machine learning within quantitative criminology, this project will provide valuable insights for policymakers, stakeholders, and practitioners working in the field of victim support and rehabilitation and may inform current legal reform efforts aimed at addressing these issues.

Helpful or harmful: The effects of criminal justice system contact on victims of sexual and physical violence

Hovedmålet med kreftbehandling er å eliminere kreftceller og dette er tradisjonelt oppnådd ved kirurgi, bruk av giftige medikamenter (cellegift) og stråling. En ny og betydningsfull tilnærming til kreftbehandling kalt immunterapi, har derimot fått mye oppmerksomhet det siste tiåret; Her forsøker leger og forskere å utnytte immunsystemet vårt for å målrettet  ødelegge kreftceller. En nøkkelaktør i denne banebrytende tilnærmingen er en gruppe «drapsmenn» i immunsystemet kjent som cytotoxiske T-lymfocytter (CTL-er). Disse cellene har en bemerkelsesverdig evne til å oppdage kreftceller ved å gjenkjenne unormale molekyler på overflaten av kreftcellene - molekyler som friske celler ikke har. Når CTL-er gjenkjenner kreftcellene ødelegger de dem ved å frigjøre giftige molekyler som initierer kreftcellenes selvdestruksjon. 
 
Selv om betydelige innsats har blitt dedikert til å forstå hvordan CTL-er aktiveres og hvordan de gjenkjenner kreftceller, vet vi mindre om de påfølgende hendelsene inne i kreftcellene som fører til deres død. Fra før vet vi at CTL-er kan initiere to forskjellige typer celledød i kreft: den første, kalt apoptose, er en stille og ordnet prosess der kreftcellene krymper og brytes opp uten å varsle immunsystemet; den andre, kalt pyroptose, er en mer dramatisk prosess som involverer dannelse av åpninger i cellemembranen, noe som fører til at cellene svulmer opp og sprekker. Under denne cellebristen blir innholdet inne i cellene frigitt i omgivelsene, og dette kan fungere som 'faretegn' som kan stimulere en sterkere immunrespons mot kreftcellene. Betydningen av denne cellebristen for å forsterke anti-tumorresponsene vil bli undersøkt i dette prosjektet. 
 
Videre er vi fascinert av muligheten for å avdekke ytterligere, ennå ukjente, former for celledød indusert av CTL-er. Utforsking av disse dødsrelaterte prosessene i kreftcellene kan potensielt øke effektiviteten av immunterapi og bidra betydelig i den pågående kampen mot kreft.

The primary goal of most cancer therapies is to induce cancer cell death. Immunotherapy relies on the cytotoxic activity of lymphocytes such as natural killer cells (NKs) and cytotoxic T lymphocytes (CTLs) to achieve this. While a significant amount of research in immunotherapy focuses on the events within cytotoxic lymphocytes or at the interface between cytotoxic lymphocytes and cancer cells, less is known about the molecular mechanisms that orchestrate cancer cell death, particularly in the case of CTL-mediated death.
CTLs are known to induce two types of cell death in cancer: non-inflammatory apoptosis and proinflammatory pyroptosis. Pyroptotic cancer cells release proinflammatory signals that attract immune cells to the tumor site, thereby enhancing the anti-tumor response. Cell lysis is a common outcome of pyroptotic cell death. It is unclear whether lysis can be decoupled from pyroptosis in cancer cells and whether the proinflammatory properties of pyroptotic cancer cell death depend on lysis. Moreover, it remains unknown whether CTLs can induce other forms of cell death in cancer, apart from apoptosis and pyroptosis.
Studying the mechanisms of CTL-mediated cancer cell death is challenging because CTLs selectively target cells expressing specific antigens. However, given the critical role of CTLs in immunotherapy, it is essential to deepen our understanding of CTL-induced cancer cell death.
This project aims to develop novel methodologies to investigate the death mechanisms that are initiated by CTLs. In addition, we will identify new pathways and mediators involved in CTL-induced cancer cell death. Furthermore, we will assess the contribution of proinflammatory cell death and lysis in promoting anti-tumor responses in vivo. Overall, this research will improve our knowledge of the molecular mechanisms of CTL-mediated cancer cell death and potentially reveal novel targets to enhance the efficacy of cancer immunotherapy.

T-cell-mediated proinflammatory cell death and lysis in cancer

Prosjektet tar sikte for å styrke og mobilisere utvalgte nærmiljøer i Ringerike kommune. Hensikten er å fremme sosial bærekraft i lokalsamfunn for en bedre og mer effektiv offentlig sektor. 

Ringerike kommune ønsker å samarbeide med Folkelig AS om en innsiktsfase for å etablere samarbeidskonstellasjoner og kartlegge innbyggerbehovet i et utvalgt nærmiljø. Vi ønsker å danne et godt grunnlag for å designe et hovedprosjekt for Ringerike kommune.

Prosjektet kan bidra med forskningsbasert kunnskap om hvilke nærmiljøkvaliteter som gir bedre ressursbruk og måloppnåelse knyttet til kommunens utfordringer. Kommunen ønsker å utvikle en modell sammen med lokalbefolkningen, sosiale entreprenører og forskningsmiljøer. Dette vil resultere i en skalerbar modell som kan benyttes i flere nærmiljøer i fremtiden. For å møte fremtidens utfordringsbilde ønsker kommunen å tenke innovativt om hvordan vi implementerer folkehelsetiltak.

Felleskapsutvikling og inkludering i Ringerike: En bærekraftig nærmiljøsatsing

The high seas are those marine areas under no State's jurisdiction. So far, all marine renewable energy (RE) activity is being conducted under State's jurisdiction. However, recent advances in technology are raising the prospect of carrying out RE activity on the high seas. Currently, only seabed mining activities in the Area have been regulated. The Area is the seabed and ocean floor beyond the limits of State's jurisdiction. From the legal viewpoint, the main gap is a lack of an international regulatory framework, informed by participatory mechanisms and supported by scientific evidence, for RE activities on the high seas, especially regarding their environmental and social impacts.  The primary project objective (O) is to provide the scientific community and policymakers with science-informed and indigenous knowledge-based recommendations in support of the development of  RE regulation on the high seas.  Two specific Os are set to complement the primary O, namely: O1 To advance the use of systematic consultation processes that facilitates research at the crossroads of marine sciences and law.  O2 To advance critical knowledge and understanding of environmental pressing issues comparable to the regulation of RE on the high seas, such as deep-sea mining in the Area. A multistep innovative methodology will be adopted, by integrating marine scientific knowledge, consultative processes, and advanced critical research in the subject matter. A case study (interdisciplinary and participatory) involving marine scientists, indigenous and coastal communities and policy makers will be conducted onboard the Research Vessel KronPrins Haakon at the beginning of the project. The case study outcomes will be analysed through critical legal analysis to build a knowledge base for policy recommendations.  The project will advance the PI’s career in an international research environment, allowing her to generate independent, high-quality, and reproducible results.   

Renewable energy on the high seas – science-informed and indigenous knowledge-based recommendations for regulatory and governance challenges

LaRiMiT - Landslide Risk Mitigation Toolbox

Optimization of Free Space Optical Communication Link based Drones for Search and Rescue Operations in the Arctic Region

The Arctic region is witnessing more frequent shipping accidents than ever which require accurate search and rescue operations. The existing communication systems use drones with radio frequency (RF) technology, which has limited bandwidth and cannot offer 4G/5G connectivity due to harsh weather constraints. It further limits the capacity of drones and affects the resolution of images and videos. The current research proposes to design free space optical communication (FSOC) link-based drones that can enhance connectivity between multiple drones and rescue ships as well as the capacity of drones to produce high resolution images and videos. The proposed FSOC-based drones can provide highspeed connectivity than the existing RF technology. The research will collect atmospheric turbulences data from the Arctic region and use it for designing the FSOC link. Furthermore, to enhance the capacity of FSOC-based drones, the research will design advanced multiplexing schemes (Mode Division Multiplexing and Orthogonal Code Division Multiple Access) and to ensure link stability, omnidirectional receiver will be designed. The research will further evaluate the performance of proposed FSOC link under the impact of various atmospheric turbulences. The expected outcomes of this research will lead to the optimisation of FSOC-based drones in expanding search areas and improving communication systems for SAR operations in the Arctic region.

Dette prosjektet, kalt Hukommelse for musikk, fokuserer på det økende antallet mennesker over hele verden som lever med demens, spesielt Alzheimer's sykdom (AD). AD starter typisk med hukommelsesproblemer og påvirker etter hvert daglige aktiviteter. Aktive musikkintervensjoner, spesielt sang, har vist positive effekter på humør, atferd og livskvalitet for personer med demens, men deres innvirkning på kognisjon er ikke godt forstått. Prosjektet har som mål å fylle dette kunnskapsgapet ved å studere effektene av å lære nye sanger på kognitiv, atferdsmessig og hjernemessig funksjon.

Studien vil omfatte hjemmeboende voksne over 65 år med AD fra Argentina, Østerrike og Norge. Deltakerne vil gjennomgå 5 måneder med intensiv musikalsk opplæring (to ganger i uken) og 5 måneder med minimal opplæring (en gang i måneden) i tilfeldig rekkefølge, med en to måneders pause imellom. Intervensjonene inkluderer å lære nye sanger med en personlig musikklærer. Generell kognisjon vil bli målt ved bruk av Alzheimer's Disease Assessment Scale - Cognitive (ADAS-cog), og hukommelse for musikk vil bli vurdert gjennom ulike metoder, inkludert atferdsoppgaver og hjerneaktivitet (EEG). Humør vil også bli evaluert i hver økt.

Målet er å inkludere 113 deltakere for å sikre pålitelig påvisning av meningsfulle effekter. Studien vil utforske hvordan humør og hukommelse for musikk bidrar til endringer i kognitive evner, og om disse effektene varierer basert på faktorer som kjønn, alder, AD-stadium, eller tidligere musikalsk opplæring og generell utdanning. Prosjektet vektlegger samarbeid mellom forskere, tjenesteytere og brukere for å sikre studiens relevans og anvendelighet.

The number of people living with dementia is increasing and is high in low, middle, and high-income countries. Alzheimer’s disease (AD), the most common type of dementia, manifests itself initially with cognitive impairment in memory domains, and later affects all activities of daily living. Active music interventions, particularly singing, can help to improve mood, behaviour problems, and quality of life. Too little is known about their effects on cognition, although some promising studies exist. The M4M project aims to fill this gap by measuring effects of learning new songs on clinical, behavioural and brain functioning. Specifically, M4M aims to examine changes in general cognitive functioning and memory for music in non-musician adults with AD undergoing intensive individual musical training based on singing novel songs, compared to minimal training.
        Home-dwelling adults with AD, 65 years or older, in 3 countries (Argentina, Austria, Norway), will receive 5 months of intensive intervention (2x/week) and 5 months of minimal intervention (1x/month), in random order, with a 2-month break in between. Interventions will entail learning new songs with an individual music teacher. At the end of each intervention period, general cognition will be measured with the Alzheimer's Disease Assessment Scale – Cognitive (ADAS-cog) by a person who is unaware of the intervention received. Memory for music will be tested with observations, behavioural tasks, and brain responses (EEG). Mood will be assessed in each session. We aim to include 113 participants; this will help us to reliably detect clinically meaningful effects. We will also examine how mood and memory for music lead to changes in cognitive abilities, and whether effects depend on sex, age, AD stage, or previous musical training or general education. M4M will be conducted in close collaboration between academic researchers, service providers, and service users to ensure relevance and applicability.

Memory for Music: Effects of individual intensive musical training based on singing in non-musicians with Alzheimer’s disease

SCAPE (Scandinavian Association for Pollination Ecology) er en årlig konferanse for forskere og studenter innen pollineringsøkologi. Det forventes deltagere fra særlig Skandinavia og resten av Europa. Men vi forventer også deltagelse fra andre deler av verden som Nord-Amerika og Asia. Konferansen legger særlig vekt på å være en arena for yngre forskere. Årets konferanse er lagt til Lofthus, Hardanger, midt i et viktig fruktdistrikt som er avhengig av pollinering for gode fruktavlinger. En tre-dagers konferanse er planlagt for å samle og utveksle kunnskap innen pollineringsøkologi. Konferansen vil bestå av foredrag, postere og en guidet tur i frukthagene. Vi har invitert to foredragsholdere/"keynotes" til å holde lengre innlegg om henholdsvis plante-pollinator interaksjoner i forhold til bærekraftsmålene og pollinatorer i jordbrukslandskapet og betydningen av forvaltning og ulik praksis.

Det 38. møtet i Skandinavisk forening for pollineringsøkologi

Evaluation of thermohydraulic characteristic of printed circuit heat exchangers in pseudocritical region for supercritical CO2 cycle

Currently, 28.2% of the total EU-28 greenhouse gas emissions come from the power sector, a large contributor to greenhouse gas emissions. Consequently, the emphasis of the research in power generation has swung towards assessing highly efficient and greener power cycles. In this reference, the novel supercritical carbon dioxide Brayton cycle (sCO2-BC) is an ideal choice that outstrips other formally well-known power cycles (Brayton & Rankine cycles). In sCO2-BC, the role of the pre-cooler is critical. It serves as a sink to the power cycle and regulates the conditions at the compressor's inlet. The compressor's inlet temperature is intended to be maintained close to the critical temperature of carbon dioxide (CO2) to achieve greater cycle efficiencies. However, exceptionally higher values of the specific heat capacity of CO2 near its critical point (up to 40 times higher than water) require exceedingly high water flow rates on the cold side to achieve the desired exit temperatures of CO2. Consequently, the pre-cooler's pumping power requirements become high enough to deteriorate the cycle's performance. This problem can only be mitigated by exploring new channel geometries with enhanced thermohydraulic characteristics. Therefore, the proposed study plan to characterize the complex thermohydraulic characteristics in the pseudocritical region of CO2 using a multifaceted technique that includes, experimental, numerical, and machine learning techniques. The proposed work will provide a step forward to the success of sCO2-BC technologies that, in turn, will facilitate its integration with the green energy resources (generation-IV nuclear reactors and solar concentrated plants), helping to meet the EU's 2030 climate and energy framework goals of achieving at least 32% share for renewable energy.

Enhancing Reliability in Onboard Satellite Processor Technology for Multi-Domain Environmental Monitoring and Commercial Applications.

Midlene fra FORNY20-FORNY2020 fordelt på år

Midlene fra FORNY20-FORNY2020 fordelt på fylker

Midlene fra FORNY20-FORNY2020 fordelt på fagområde

Prosjektet "TychoBoB", som drives av Tycho Space Technologies sikter mot å fremme satellitteknologi som kan ha nytte i flere sektorer, inkludert miljøovervåkning og romutforskning. Sentralt i dette initiativet er utviklingen av en robust ombordprosessor som kan brukes på overvåkingsplattformer i verdensrommet, luftfart, og maritime miljøer.

Det primære målet er å oppgradere prosessorteknologien for å møte internasjonale standarder for pålitelighet, fastsatt av organisasjoner som den Europeiske Romfartsorganisasjonen (ESA).  Et sekundært, men like viktig mål, er å utvilke plattformen slik at den kan brukes i flere miljøer – enten i verdensrommet, i atmosfærer eller over og under havet. Denne kapabiliteten er spesielt avgjørende for overvåkning og beskyttelse av økosystemer, spesielt marine miljøer som ofte er vanskelige å overvåke og studere over tid.

Ved å takle disse utfordringene vil "TychoBoB"-prosjektet fremme teknologisk innovasjon og bidra til sentrale sammfunnsoppdrag innenfor havrommet. Teknologien som utvikles kan sikre tilgang på essensiell data for miljøvern, forbedre sikkerheten og effektiviteten i maritime operasjoner, og utvide våre kapasiteter til bærekraftig bevaring av havressurser.

Reliability and multi-domain applications in a small satellite onboard processor.

The suggested conference will serve as a dedicated international meeting place for researchers interested in crowdfunding. Here, despite immense growth of interest in the field and publication volumes in recent years, crowdfunding-dedicated conferences have been rare outside practitioner circles. Hence, we will create a new dedicated forum for crowdfunding researchers across disciplines linking information systems, economics, finance, entrepreneurship, marketing, psychology and sociology researchers under one roof to exchange ideas and help develop the field both theoretically and practically. 

Furthermore, the conference will invite industry representatives and public policymakers to participate in panel discussions with researchers. Such discussions may facilitate better dialogue between these actors and allow to address the most urgent issues on each stakeholder's agenda in a complementary way.

The conference is expected to include research presentations on themes including the following: (1) crowdfunding adoption by fundraisers – drivers and barriers; (2) crowdfunding platform design and development; (3) artificial intelligence applications in crowdfunding; (5) drivers and barriers to contribution behaviour; (6) predictors of crowdfunding campaign success; (7) gender aspects in crowdfunding behaviour; (8) civic crowdfunding and public institution use of crowdfunding; (9) crowdfunding sustainability; (10) crowdfunding energy, renewable energy, and climate mitigation; (11) ethical issues in crowdfunding practice; (12) crowdfunding regulations and their implications for practice; and (13) collaboration and cooperation between traditional financial institutions and crowdfunding platforms.

The event will be organized as a two-day conference scheduled for 30.11-01.12.2022. Each day will follow a schedule of 3 sessions for paper presentations (5 papers in each) + 1 invited key note speech + 1 stakeholder panel discussion  + Lunch  + 3 coffee breaks .

International Conference on Crowdfunding Research

UiA will host the 7th Annual conference of the Europe-Mediterranean Research Business Institute (EMRBI) in Kristiansand during Fall 2014.

The conference attracts approximately 250 scholars and policy makers, within the fields of Economics, Business Admin istration, and Management. Participants arrive from all over the world, but primarily from European and Mediterranean countries.

The 2014 conference theme will be: The Future of Entrepreneurship - Emerging Challenges and Opportunities in Europe and Beyon d. 

Accordingly, while the conference will include multiple tracks welcoming studies from a variety of business and management disciplines, it will especially welcome submissions addressing both current knowledge domains of entrepreneurship, as well as f uture developments, challenges and opportunities for entrepreneurship in general, and in the European context in particular.
 
Such event is well timed to address urgent questions which involve academia, government and industry in a period of economic slo wdown and uncertainty in Europe.  This urgency and interest are captured by initiatives such as the European Community's Entrepreneurship 2020 Action Plan, as well as in various programs of Norwegian government bodies (i.e. Innovasjon Norge projects, Mer  Entreprenørskap, Ungt Entreprenørskap, etc.).

The event itself will be based on two days of intensive parallel sessions. Each day will have four 1,5 hour sessions. In each session, 5 thematic tracks will run in parallel. Each session will include of 4-5  paper presentations, and will be managed by a track chair and discussant. All in all, 150 papers are expected to be presented in 30 sessions.

0 projects

IKTPLUSS-IKT og digital innovasjon

International Conference on Crowdfunding Research

Awarded: NOK 99,999

Project Period: 2022-2022

Location: Agder

FRIHUMSAM-Fri prosj.st. hum og sam

Hosting the 7th Annual Conference of the Europe-Mediterranean Research Business Institute (EMRBI) at the University of Agder

Awarded: NOK 0.20 mill.

Project Period: 2014-2014

Location: Agder