0 projects

STAMCELLER-Stamcelleforskning

Principles of stem cell pathway heterogeneity in tumor sub-populations

There is an ongoing debate on heterogeneity of stem cell parameters in tumor cells and the existence of tumor stem cells. The enclosed project proposal uses cell cycle parameters and stem cell pathways to analyze and determine mechanisms for creating and maintaining cell heterogeneity in tumors....

Awarded: NOK 3.0 mill.

Project Period: 2009-2012

Location: Oslo

RBGRUNTEKN-Res.bas.grunnbev.tekn-ind.inst

Grunnbevilgning Stiftelsen SINTEF (Tekn.-ind.)

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Awarded: NOK 2.2 bill.

Project Period: 2009-2022

Location: Trøndelag - Trööndelage

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Nordic Network for Studies in Pediatric Obsessive- Compulsive Disorder (OCD) Neurobiology, Genetics and Treatment

OCD a serious often chronic condition with onset mostly in childhood and adolescence entails considerable suffering and impairment. Adult OCD is the 10:th most common reason for disability from illness and most adults with OCD report onset in childhood or adolescence. The etiology involves inter...

Awarded: NOK 1.5 mill.

Project Period: 2008-2013

Location: Oslo

GLOBHELS-Global helse

Developing vaccines against diarrhea caused by Enterotoxigenic Escherichia coli and Shigella (EntVac)

Diarrhea and dysentery are important killers of children in developing countries. These diseases also contribute to malnutrition. Vaccines give a very favorable return on public health investment, and a polyvalent anti-diarrheal vaccine would greatly impr ove this investment case. But efforts to ...

Awarded: NOK 15.2 mill.

Project Period: 2008-2014

Location: Vestland

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Dissecting molecular properties of honey bee vitellogenin (Vg): a protein acting at the intersection between social behavior and aging

The honey bee provides opportunities for cutting-edge studies of the molecular basis for complex social traits. Our group has made substantial contributions to the understanding of honey bee behavior and aging by identifying a socially controlled pathway that affects social activities and aging r...

Awarded: NOK 4.1 mill.

Project Period: 2008-2012

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Genome sequencing of cod by exclusive use of ultra-high-throughput sequencing technology

We propose a project characterized by exclusive use of new ultra-high-throughput sequencing technology combined with state-of-the art bioinformatics algorithms designed for maximal exploitation of this technology. The project will be carried out in close collaboration with 454 Life Sciences, the...

Awarded: NOK 10.0 mill.

Project Period: 2008-2012

Location: Oslo

NANOMAT-Nanoteknologi og nye materialer

Laccase-Nanoparticle Conjugates for the Elimination of endocrine disrupting chemicals from wastewater in bioreactors.

The following NANOMAT project represents the Norwegian part of the MATERA project called LANCE. The overall objective of this project is to develop a new method for the elimination of very persistent xenobiotics, such as endocrine disrupting chemicals, du ring the wastewater treatment. The concep...

Awarded: NOK 3.5 mill.

Project Period: 2008-2011

Location: Trøndelag - Trööndelage

EUROSTARS-EUROSTARS

Pain Detector E4260

Med-Storms unique Pain Detector is the only medical device available for recording and quantify pain during pain management. The clinical and technical development of the Pain Detector will address the demand for the mandatory pain recording and treatmen t in the US. Pain is difficult to manage ...

Awarded: NOK 1.5 mill.

Project Period: 2008-2011

Location: Oslo

HAVBRUKS-Havbruk - en næring i vekst

InNoVacc. Indo-Norway platform for developing candidate vaccines to invertebrate, piscine and avian species.

Vaccination is essential to large-scale control of infectious diseases affecting commercial aquatic and avian farming. Nevertheless, modern aquaculture lacks effective vaccines against several pathogens due to lack of understanding of their immune system and development of effective immunostimula...

Awarded: NOK 33.0 mill.

Project Period: 2008-2013

Location: Oslo

BIA-Brukerstyrt innovasjonsarena

Development of anti-cancer drug candidate using biosynthetic and chemical engineering

Leukemia is one of the major types of cancer with over 330.000 new incidences each year worldwide. Therapeutic options for treating leukemia are relatively limited, and there exists an unmet need in safe and efficient anti-leukemic drugs. The major goal o f the proposed project is to develop an a...

Awarded: NOK 4.2 mill.

Project Period: 2008-2010

Location: Trøndelag - Trööndelage

NEVRONOR-Nasjonal satsing på nevrovitenskap f

Building national and international networks in aquaporin research: from in vivo two-photon imaging to gene analysis in patient cohorts

A number of neurological and psychiatric diseases for which current therapies are nonexisting or inadequate involve deficiencies in water homeostasis or cerebral blood flow regulation. Examples are headache disorders, epilepsy and Alzheimer`s disease. The recent Nobel-recognized discovery of aqu...

Awarded: NOK 3.1 mill.

Project Period: 2008-2011

Location: Oslo

HAVBRUKS-Havbruk - en næring i vekst

Genomics in Aquaculture - International symposium at the Bodø University College

Aquaculture genomics has potential applications in improving performance traits, including increased disease resistance and growth rate. The number of genomic resources available for species of commercial interest has been increasing at a remarkable pace. These include framework genetic linkage ...

Awarded: NOK 0.20 mill.

Project Period: 2008-2010

Location: Nordland - Nordlánnda

EUROSTARS-EUROSTARS

4353 Environmently-friendly technology for collagen production from freshwater fish by-products

The main research and development work in the project includes: 1) technological research for development of technique for high-yield extraction of collagen from freshwater fish by-products using environmental-friendly regents, 2) technological research f or development of technique for purificat...

Awarded: NOK 0.90 mill.

Project Period: 2008-2011

Location: Trøndelag - Trööndelage

HAVBRUKS-Havbruk - en næring i vekst

Indo-Norwegian platform on fish and shellfish vaccine development

Infectious diseases have a significant impact on the sustainability of the aquaculture industry, that being in finfish or shellfish/shrimp production environments. The subsequent use of antibiotics, drugs, and chemical disinfectants cause concern at all l evels. The succesful vaccines for salmon ...

Awarded: NOK 44.0 mill.

Project Period: 2008-2013

Location: Troms - Romsa - Tromssa

NEVRONOR-Nasjonal satsing på nevrovitenskap f

ESF - Stress and Mental Health (EuroSTRESS) - støttes av NevroNor

Repetitive and uncontrollable stress is known to be a powerful risk factor for mental disorders. Whether an individual will respond adaptively or maladaptively to a stressor is de?ned by his/her genetics, developmental history and the environment in adult hood. In particular traumatic experiences...

Awarded: NOK 2.8 mill.

Project Period: 2008-2013

Location: Vestland

NAERINGSPH-Nærings-phd

Targeted lytic peptides - a new class of molecules designed for lysis of mitochondria in tumor cells

Despite monumental efforts in finding and developing cures, cancer is still a common and life threatening disease; one in three will get cancer and one in five will die of it. Lytix Biopharma AS is developing drugs for treatment of cancer and infection based on lytic peptides and peptidomimetic...

Awarded: NOK 1.1 mill.

Project Period: 2008-2014

Location: Oslo

BIONÆR-Bionæringsprogram

Food restrictions of allergic patients resolved by a novel type vaccine.

The project aims to improve the diagnostic tools for food allergy and the methods of detection of allergens in foods and, most importantly, to investigate a vaccine for food allergy. The current diagnostic tools include skin tests in which food extracts are applied to the skin. These methods are...

Awarded: NOK 4.4 mill.

Project Period: 2008-2013

Location: Akershus

MILPAAHEL-Miljøpåvirkning og helse

Nutrients, genes and epigenetic modification of DNA in relation to asthma and atopy.

This project is based on the Norwegian Mother and Child Cohort Study (MoBa). While limited human evidence is available on the association of childhood atopic diseases with maternal diet during pregnancy and gene methylation in the offspring, new murine st udies from our collaborators at the Natio...

Awarded: NOK 4.3 mill.

Project Period: 2008-2014

Location: Oslo

HAVBRUKS-Havbruk - en næring i vekst

Exploiting new knowledge of innate immunity in adjuvant research for bovine vaccines

Bovine tuberculosis is still a major problem in large parts of the world. The infection leads to cattle mortality and is also a zoonosis. The proximity between people and humans in small-holder farmers in countries like India make them especially at risk of catching bovine TB. While testing and s...

Awarded: NOK 6.8 mill.

Project Period: 2008-2013

Location: Akershus

MATPROG-Matprogrammet: Norsk mat fra sjø og land

Videreutvikling av produkttilpasset CO2-emitter tilpasset modifisert atmosfærepakket kjøttprodukter og ulike pakkemetoder for sjømatprodukt

Hovedmålet er økt kunnskap for å videreutvikle og utvide anvendelsesområdet til norsk produsert CO2-emitter for sjømat og kjøttprodukter. CO2-emitteren utvikler CO2-gass i pakningen som vil bidra til å beholde/øke produktkvaliteten og holdbarhet, samt red usere ineffektiv emballering og distribus...

Awarded: NOK 1.5 mill.

Project Period: 2008-2010

Location: Møre og Romsdal

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Pelvic girdle pain in pregnancy: Endocrine risk factors, physical activity and prognosis.

Background: Pelvic girdle pain affects one in five pregnant women, gives rise to functional disabilities and is a major cause of sick leave in pregnancy. Hence, pelvic girdle pain should be regarded as a major women's health issue. Nevertheless, the aetio logy is poorly understood. Pregnancy repr...

Awarded: NOK 3.6 mill.

Project Period: 2008-2012

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Information material for public health care professionals

We would like to produce information material for physicians, midwives and other health care workers who meet the couples before, during and after their pregnancy. We would like to make information folders and also write in journals read by the health car e professionals. We would also like to ma...

Awarded: NOK 0.15 mill.

Project Period: 2008-2010

Location: Vestland

NEVRONOR-Nasjonal satsing på nevrovitenskap f

The Autism Database

The prevalence of autism spectrum disorders (ASD) has increased approximately 10-fold over the past 20 years, now affecting about 60 pr 10 000 children. ASDs are highly heritable neurodevelopmental disorders, with environmental factors possibly functioni ng as triggers in genetically susceptible...

Awarded: NOK 1.00 mill.

Project Period: 2008-2013

Location: Oslo

NAERINGSPH-Nærings-phd

Percutaneous access and connection to visceral organs

Surgical treatment of inflammatory bowel diseases (ulcerative colitis and Crohns disease), familiar polyposis and large bowel cancer often requires partial or total removal of the affected organ with formation of a stoma for collection of the intestinal c ontents. For patients with congenital mal...

Awarded: NOK 1.4 mill.

Project Period: 2008-2012

Location: Oslo

HAVBRUKS-Havbruk - en næring i vekst

Transmission and reservoirs of Francisella piscicida. Implications for wild and farmed cod.

A new species of Francisella (F. piscicida), causing mortality in farmed cod (Gadus morhua), was isolated autumn 2004 from farmed cod in Rogaland. In 2005 this bacterium was isolated from several cod farms in Rogaland, Hordaland, Møre og Romsdal, Nordland and Denmark and from Atlantic salmon in ...

Awarded: NOK 2.2 mill.

Project Period: 2008-2013

Location: Vestland

HAVBRUKS-Havbruk - en næring i vekst

Francisella philomiragia subsp. noatunensis infection in farmed cod (Gadus morhua): Diagnosis, characterisation, and environmental studies

Farming of marine fish species in Norway is currently going through what may be described as a boom period. A combination of technological innovation in the field of larval production, combined with regulated wild-fisheries and concurrent favourable marke t prices, have made farming of marine spe...

Awarded: NOK 3.3 mill.

Project Period: 2008-2011

Location: Akershus

FUGE-Funksjonell genomforskn.i Norg

Identification of key antiviral and inflammatory modulators in Atlantic cod (Gadus morhua L.)

Atlantic cod has recently been introduced into aquaculture in Norway and is expected to constitute a major part of Norwegian fish farming within few years. Expansion of this industry faces many challenges, including disease problems. From farming of salmo nids we know that vaccination has been a ...

Awarded: NOK 5.3 mill.

Project Period: 2008-2011

Location: Troms - Romsa - Tromssa

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Activity-dependent plasticity in visual cortex

A major question in neuroscience is how appropriate connections are formed when the brain develops. It is well established that neural circuits are fine-tuned by experience during 'critical periods' in early postnatal life. In the visual system, closing o ne eye for only a few days during a criti...

Awarded: NOK 2.7 mill.

Project Period: 2008-2012

Location: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Speciation processes in fungi examined through experimental and empirical approaches

Although more than 100.000 fungal species exist, fungi are largely missing in the speciation debate. Speciation theory is based mainly on research on animals and plants and little is known whether fungi conform to general models of speciation. Four differ ent boreal/nemoral wood-decay species com...

Awarded: NOK 3.3 mill.

Project Period: 2008-2012

Location: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

B-cell lymphomagenesis in Ung-deficient mice: collaboration between chronic antigenic stimulation and DNA repair deficiency

The importance of responding appropriately to DNA damage is highlighted by the frequent development of human disease, most notably cancer, in cells where this response is compromised. Here, we ask whether endogenous DNA damage, such as uracil in DNA, can contribute to activation of the DNA damage...

Awarded: NOK 6.4 mill.

Project Period: 2008-2013

Location: Oslo