203 projects

Date from new to old

HELSEFORSKNING-Helseforskning

Development Of Patient-derived organoid PLatforms for Evading Resistances in Lung Cancer

Lung cancer remains the leading cause of cancer death globally. Despite advancements in targeted therapies for oncogene drivers like EGFR and KRAS mutations, both intrinsic and acquired resistance ultimately limit their effectiveness. While in vitro studies using 2D cultures have identified resis...

Awarded: NOK 3.5 mill.

Project Period: 2025-2028

Location: Trøndelag - Trööndelage

FOFORMIDLING-FOFORMIDLING

Forskningstorg om kropp og sinn

Forskningsmiljøer fra flere helserelaterte institusjoner ved UiO samarbeider om å gi publikum en engasjerende dag med kunnskap og aktiviteter om kropp og sinn gjennom å lage og bemanne boder med forskjellige forskningsaktiviteter. Kunnskap om hva som gir god helse og bærekraftig behandling av u...

Awarded: NOK 40,000

Project Period: 2025-2025

Location: Oslo

HELSEFORSKNING-Helseforskning

Mechanisms of resilience and vulnerability to environmental challenges in mental health

Childhood adversities can have a profound impact on mental health, extending far into adulthood. These early challenges, such as trauma or neglect, can increase the likelihood of experiencing mood disorders or anxiety later in life. However, the story isn't the same for everyone. While some indiv...

Awarded: NOK 3.3 mill.

Project Period: 2025-2028

Location: Oslo

FOFORMIDLING-FOFORMIDLING

Forsker Grand Prix UiO MED 2025

Hovedmålsetningen med dette prosjektet er opplysende og engasjerende forskningsformidling for publikum, både under prosjektperioden og gjennom deltakernes videre forskningskarriere. 10 deltagere får en fantastisk mulighet til å lære mer om hvordan de når fram med budskapet sitt til et stort publi...

Awarded: NOK 0.10 mill.

Project Period: 2025-2025

Location: Oslo

UTVIKLING-UTVIKLING

Advancing tuberculosis diagnosis in children and adults by developing point-of-care optical devices

Tuberculosis (TB) remains a persistent global health challenge, especially for low and middle-income countries (LLMICS). A significant obstacle in controlling TB is the unavailability of a point-of-care TB diagnostic test. Currently used diagnostic tests necessitate advanced and expensive laborat...

Awarded: NOK 12.0 mill.

Project Period: 2025-2029

Location: Vestland

HELSEFORSKNING-Helseforskning

Biocide Impact on Antimicrobial Resistance in Enterobacterales in One Health settings

Antimicrobial resistance (AMR) is now a common occurrence in many settings, such as hospitals, food production sectors , the environment, and in the human and animal populations. As these settings are interconnected, AMR can be transmitted between them, either by the bacteria itself, or by the ge...

Awarded: NOK 3.4 mill.

Project Period: 2025-2027

Location: Akershus

SYSTEMET-INT-SYSTEMET-INT

Raskere og bedre sårheling hos hest med autologe hudkomponenter

Limb wounds in horses are common, however healing is exceedingly slow and fraught with complications. Contrary to body wounds, limb wounds demonstrate only a small amount of wound contraction. The specialist procedure of applying partial-thickness skin grafts to limb wounds stimulates wound contr...

Awarded: NOK 0.15 mill.

Project Period: 2025-2025

Location: Akershus

FORSKNINGSINFRA-FORSKNINGSINFRA

Norwegian Brain Initiative (NORBRAIN) – a large-scale infrastructure for 21st century neuroscience: Stage 4

Neuroscience is one of a few scientific disciplines where Norway is at the leading edge. The discipline is currently evolving faster than almost any other discipline, and this development is reflected in the steady invention of new technology for investigation of the brain. A condition for mainta...

Awarded: NOK 80.3 mill.

Project Period: 2025-2034

Location: Trøndelag - Trööndelage

LANDBASERT-LANDBASERT

HESTEFORSK - Raskere og bedre sårheling hos hest med autologe hudkomponenter

Limb wounds in horses are common and are notoriously difficult to treat due to their slow healing rate and the frequent occurrence of healing complications such as infection and exuberant granulation tissue formation. Consequently, limb wounds cause significant animal suffering, as well as repres...

Awarded: NOK 0.98 mill.

Project Period: 2024-2027

Location: Akershus

FORMIDLING-Allmennrettet formidling

Forskningstorg om kropp og sinn. Premier til forskningstorgets quiz og til markedsføring av torget, quizen og premier.

Forskningsmiljøer fra fire ulike helserelaterte institusjoner ved UiO samarbeider om å gi publikum en engasjerende dag med kunnskap og aktiviteter om kropp og sinn gjennom å lage boder med forskjellige forskningsaktiviteter. Her er det mulighet for alle typer aktiviteter som egner seg for å eng...

Awarded: NOK 23,000

Project Period: 2024-2025

Location: Oslo

REKRUTTERING-REKRUTTERING

Svinesjekk: Ny kunnskap for bedret tilsyn med norske svinebesetninger

Good animal welfare is an important factor in modern and sustainable food production. The public interest in animal welfare is increasing, both in Norway and internationally. There has been growing interest from consumers regarding where the food was made, the welfare of farmed animals and their ...

Awarded: NOK 2.0 mill.

Project Period: 2023-2026

Location: Innlandet

INTSAMARBEID-INTSAMARBEID

Impact of Diving on Vascular Health

Diving exposes the human body to physical stress that initiate a range of phyiological and biochemical responses. Much of the maritime and marine industry still completely rely on diving and will so for many years ahead. It is therefore key to understand possible negative health effects of this o...

Awarded: NOK 93,999

Project Period: 2023-2025

Location: Vestland

INNO-NAERING-INNO-NAERING

Ready-to-Use formulation of Sonazoid for contrast enhanced ultrasound imaging and therapy

Sonazoid is a world leading contrast agent for medical ultrasound (US) imaging comprising microbubbles, and is currently manufactured as a freezedried product, meaning that the end user (hospital nurse or pharmacy) has to reconstitute the product with water prior to use. Furthermore, the freezedr...

Awarded: NOK 16.0 mill.

Project Period: 2022-2026

Location: Oslo

HELSEFORSKNING-Helseforskning

Understanding brain circuit dysfunction in amblyopia using large-scale multimodal recordings in a new visuomotor task.

Some theories about brain function consider the brain as a prediction machine. Based on previous experience, our brains may perform an "autocompletion" function during pretty much every thing we do, and perhaps, think. Here we will study amblyopia, or best known as "lazy eye" in a mouse model to ...

Awarded: NOK 3.0 mill.

Project Period: 2022-2025

Location: Oslo

INTSAMARBEID-INTSAMARBEID

MoBaBrain: National network for brain development and increased societal impact

Childhood and adolescence are periods characterised by biological changes and major life transitions. For some individuals these periods are also associated with increased risk of developing mental disorders. Indeed, 50% of adult patients report having experienced symptoms before 14 years of age ...

Awarded: NOK 0.80 mill.

Project Period: 2022-2025

Location: Oslo

HELSEFORSKNING-Helseforskning

Ionophore coccidiostats: risk of CO-selectioN of antImicrobial resistance - Clinical impact and intervention strategies

Antimicrobial resistance is one of the world's most serious threats. Insight in the development, dispersal and prevention of antimicrobial resistance is of great importance for both public and animal health, food safety and sustainability. In Europe, ionophores are regulated as coccidiostats and...

Awarded: NOK 7.0 mill.

Project Period: 2022-2025

Location: Akershus

HELSEFORSKNING-Helseforskning

Use of phage applications to combat MRSA at the sow-piglet interface to reduce exposure of staff and contamination of the environment

The greatest risk of humans acquiring methicillin-resistant Staphylococcus aureus (MRSA) from livestock is through direct contact with infected animals or contaminated environments, including airborne exposure. In pig production, sows (female pigs) are at the top of the production chain and, once...

Awarded: NOK 0.91 mill.

Project Period: 2022-2025

Location: Akershus

POS-ERC-Støtte til ERC-søkere som oppnår god evaluering

FINALphagy-resubmission

When an organism experiences physiological stresses, such as nutrient starvation, it activates several mechanisms to promote its survival. One of these mechanisms is autophagy, which is a catabolic pathway conserved from yeast to man that functions as a recycling system during normal physiology, ...

Awarded: NOK 0.22 mill.

Project Period: 2021-2022

Location: Oslo

FRIPROSJEKT-FRIPROSJEKT

Rational vaccine design as an approach to protect against PMCV infection in salmon

Totivirus represent en group of viruses that typically infect protozoa, fungi, and some vertebrate species. Salmon are infected with a virus called piscine myocarditis virus (PMCV), which resembles totivirus and has acquired the ability to spread between hosts, a capability lacking in most totivi...

Awarded: NOK 12.0 mill.

Project Period: 2021-2029

Location: Ukjent Fylke

FRIPROSJEKT-FRIPROSJEKT

Multiomic 4-dimensional identification of novel treatment targets for bile duct inflammation

Primary sclerosing cholangitis (PSC) is a severe and chronic bile duct disorder without medical treatment. Therefore, there is a critical need for new targets for treatment, to define these properly an increased understanding of the disease process is needed. In general, development of disease is...

Awarded: NOK 12.0 mill.

Project Period: 2021-2028

Location: Oslo

UTVIKLING-UTVIKLING

Improving implementation and operation of a One Health platform to combat rabies in Malawi

Dog-mediated rabies in humans is a completely preventable, deadly disease that disproportionately affects rural communities, particularly children, of economically disadvantaged areas of the world. It is not lack of science that stands in the way of successful rabies control, it is the failure ...

Awarded: NOK 12.0 mill.

Project Period: 2021-2026

Location: Akershus

FRIPROSJEKT-FRIPROSJEKT

Pack a pill in a PACA: PACA nanomedicines for targeting age-related changes in liver endothelium to prevent age-related diseases

When we age, we have numerous reduced, or even loss of, bodily functions. The liver is no exception - despite being one of the most robust organs in the body, the liver also ages. One such age-affected function is the communication between the blood and the liver's major cells, the hepatocytes. I...

Awarded: NOK 12.3 mill.

Project Period: 2021-2026

Location: Troms - Romsa - Tromssa

STIM-OA-Stimuleringstiltak for åpen tilgang

Dekking av UiTs utgifter til APC i gull OA-tidsskrifter for 2020

Delfinansiering av UiTs utbetalinger til finansiering av APC i gull OA-tidsskrifter fra UiTs publiseringsfond i regnskapsåret 2020.

Awarded: NOK 1.5 mill.

Project Period: 2021-2021

Location: Troms - Romsa - Tromssa

FRIPROSJEKT-FRIPROSJEKT

Immune-driven regeneration: harnessing regulatory T cells to enhance the efficacy of mesenchymal stem cell-based bone regeneration

Millions of people visit hospitals worldwide annually to receive bone grafts to treat bone diseases and defects. This raises a huge burden on any society. The discovery of stem cells, which are special cells from which all other functional cells are produced, has been a revolution in the bone reg...

Awarded: NOK 8.0 mill.

Project Period: 2021-2026

Location: Vestland

FRIPROSJEKT-FRIPROSJEKT

Axonal dysfunctions in Dravet Syndrome

Dravet syndrome is a severe form of childhood epilepsy. During an initial period of normal development, infants suffering from Dravet syndrome develop epileptic seizures at about half a year of age, often in combination with fever (so called febrile seizures). During the first years of life, pati...

Awarded: NOK 8.0 mill.

Project Period: 2021-2025

Location: Oslo

HELSEFORSKNING-Helseforskning

Tactile sensory impairment of C-LTMR afferents in preterm children

Gentle touch is an important part of maternal care: it comforts, calms, and enables regulation of arousal in newborns. A special group of nerve fibers is crucial for humans - like other mammals - to perceive and enjoy slow, pleasant stroking. These are called C-LTMR nerve fibers. This project has...

Awarded: NOK 4.2 mill.

Project Period: 2021-2025

Location: Oslo

HELSEVEL-H-Gode og effektive helse-, omsorgs- og velferdstjenester

One Health in the 21st Century 2021

Over the course of the past decade, a number of global agencies, including the World Health Organization, the Food and Agriculture Organization, the World Organisation for Animal Health, the United Nations Environment Programme, and the World Bank, have endorsed, mobilized, and advanced a number ...

Awarded: NOK 0.30 mill.

Project Period: 2021-2021

Location: Oslo

FRIPROSJEKT-FRIPROSJEKT

What is the role of astroglial calcium signaling in hippocampal memory encoding?

How do you remember what you did yesterday or even twenty years ago? A landmark discovery in memory research revealed that neural activity patterns of daily life experiences repeat themselves when we are asleep. Such reactivations, or replay, are important for long-term memory and is a well-accep...

Awarded: NOK 8.0 mill.

Project Period: 2021-2025

Location: Oslo

IS-AUR-Samarb.progr. mellom Norge og Frankrike

Exploring the interplay between textures and touch velocity in tactile perception.

This project aims to lay the ground for a larger project to investigate how texture and touch velocity shape subjective perception and experience. Together with early-career researchers, pilot data will be collected and analysed, before both groups meet for presentation of the data at the IASAT m...

Awarded: NOK 63,257

Project Period: 2021-2022

Location: Oslo

HAVBRUK2-Stort program for havbruksforskning

Mattrygghet:Developing fish-food safety control measures against antimicrobial resistance by reprogramming metabolism in farmed fish

Antimicrobial resistance (AMR) is one of the greatest public health threats facing humanity. Several microorganisms that were once susceptible to antibiotic treatment are now resistant to various antimicrobials. In the present study, we collected marine environmental samples and farmed fish sampl...

Awarded: NOK 4.8 mill.

Project Period: 2021-2025

Location: Akershus

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