0 projects

MARINFORSK-Marine ressurser og miljø

Fisheries induced evolution in Atlantic cod investigated by ancient and historic samples

I dette prosjektet har hovedmålet vært å kvantifisere de evolusjonære selektive effekter som industrielt fiske kan ha hatt på torsk, hvor vi sammenligner sekvenseringsdata fra historiske prøver med nålevende bestander av torsk. De historiske prøvene er fra det 20. århundre samt fra begynnelsen av...

Awarded: NOK 6.0 mill.

Project Period: 2011-2017

Location: Oslo

MILPAAHEL-Miljøpåvirkning og helse

Searching the origin of the insulin resistance syndrome

Persistent organic pollutants (POPs) are toxic and hazardous chemicals omnipresent in our environment and food chains. These pollutants are of particular public health concern since their bio-accumulate in humans for many years because of their resistance to metabolic degradation. Recently, expo...

Awarded: NOK 2.0 mill.

Project Period: 2011-2013

Location: Vestland

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Genetic architecture in Drosophila - The role of the Y chromosome in gene expression across the genome.

Understanding genetic architecture, the underlying basis of phenotypic traits, and its relationship to evolutionary change, is a major challenge for evolutionary biologists. Variation in gene expression is one of the most important factors causing phenoty pic variation. We will study the role of ...

Awarded: NOK 3.2 mill.

Project Period: 2011-2014

Location: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Biololgical methane oxidation by methanotrophic Verrucomicrobia under hot and acidic conditions; evolution of an ancient metabolic trait

Methylacidiphilum representerer en ny utviklingslinje av ekstremofile metanoksyderende bakterier tilhørende fylumet Verrucomicrobia. Disse bakteriene er ekstremt acidofile (syreelskende) og vokser i geotermale miljø med pH ned til 1 og under. De er moderat termofile (varmeelskende). Gruppen er fj...

Awarded: NOK 3.3 mill.

Project Period: 2011-2015

Location: Vestland

MILJØ2015-Norsk miljøforskning mot 2015

LAND: Partial migration of red deer and tick distribution at the altitudinal colonization border (TickDeer)

Det overordnete målet for prosjektet «TickDeer» er å forstå betydningen av hjortens trekk for flått og omvendt i områder nær den høydemessige begrensningen i utbredelse. (WP1) Omfattende data på flåttens fordeling (>15000) i landskapet har dannet basis for PhD graden til Lars Qviller (levert, dis...

Awarded: NOK 4.7 mill.

Project Period: 2011-2015

Location: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

The adaptive evolution of arthropod and vertebrate aquaporins: Deciphering the differential basis of water homeostasis

Innledende studier fokusert på å identifisere de genomiske repertoar av akvaporiner i et bredt spekter av prokaryote og eukaryote organismer for å legge grunnlaget for å forstå den evolusjonære historien til superfamilen, og for å identifisere alle akvaporin gener i lakselusa og sin vert, den atl...

Awarded: NOK 9.6 mill.

Project Period: 2011-2015

Location: Vestland

IS-AUR-Samarb.progr. Norge Frankrike

Genomic dissection of seed development

Parent of origin dependent expression plays an important role in seed development of flowering plants, and disruption of imprinted genes typically leads to developmental abnormalities often resulting in abortion of the seed. We have used a mutant in the A rabidopsis Cdc2/CDC28 homologue, CDKA;1 a...

Awarded: NOK 97,853

Project Period: 2011-2013

Location: Oslo

IS-BILAT-Mobilitet Norge-USA /Canada

Phylogeography of vent, seep and fall species in the North Atlantic

Hydrothermal vents are unique biological systems driven on geothermal energy instead of solar power. The vent fauna seems to be related to fauna inhabiting hydrocarbon seeps and whale- and wood-falls. New vent areas, representing a completely new biogeogr aphic region were recently discovered nor...

Awarded: NOK 0.32 mill.

Project Period: 2010-2011

Location: Vestland

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Characterization of the role of the small GTPase Rab7b in intracellular traffic.

Intracellular trafficking is regulated by Rab proteins. More than 60 human Rabs have been identified but until now there has been no Rab assigned to the transport from TGN to late endosomes/lysosomes. In our recent work (Progida et al, under revision), we show that Rab7b is a strong candidate fo...

Awarded: NOK 3.4 mill.

Project Period: 2010-2013

Location: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Genome size, cell size and growth; searching for the causal links

We here aim both at exploring the causal links between growth rate, genome size and cell size and the evolutionary drivers for reduced genome size. There are likely several routes to genome size variability within and across taxa. Here, we are mainly inte rested in the observation that meiosis an...

Awarded: NOK 8.6 mill.

Project Period: 2010-2014

Location: Oslo

FORINFRA-Nasj.sats. forskn.infrastrukt

Research Infrastructure for High-Precision Palaeoecological Analyses

Palaeoecology is the ecology of the past and is concerned with the reconstruction of past flora, fauna, populations, communities, landscapes, and environments and with the understanding of the causes of observed changes seen in the palaeoecological record preserved as fossil pollen, seeds, and a...

Awarded: NOK 10.3 mill.

Project Period: 2010-2015

Location: Vestland

FUGE-Funksjonell genomforskn.i Norg

Application for support of the annual contact meeting of the Norwegian Biochemical Society.

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Awarded: NOK 0.36 mill.

Project Period: 2010-2012

Location: Oslo

HAVBRUKS-Havbruk - en næring i vekst

Cod Development CODE

CODE er en kunnskapsplattform der ni norske og flere internasjonale universiteter og forskningsinstitusjoner deltar. CODE har som hovedmål å få en dypere forståelse av utviklingsprosesser i torsk samt hvordan miljøfaktorer (ernæring og temperatur) påvirker utviklingen. En viktig del av arbeidet b...

Awarded: NOK 21.0 mill.

Project Period: 2010-2015

Location: Vestland

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Surviving without oxygen - from the role of hypoxia inducible factor to rebuilding a naturally damaged brain

While medical science has had a very limited success in counteracting the deleterious effects of ischemia/hypoxia in humans, evolution has repeatedly solved this problem. The best studied examples of anoxia tolerant animals are some North American freshwa ter turtles (genera Trachemys and Chrysem...

Awarded: NOK 6.4 mill.

Project Period: 2010-2013

Location: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Phytoplankton size: Climatic adaptation and long-term evolution

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Awarded: NOK 4.5 mill.

Project Period: 2010-2014

Location: Oslo

HAVKYST-Havet og kysten

Spatiotemporal variability in mortality and growth of fish larvae in the Lofoten-Barents Sea ecosystem

The potential risk for fisheries imposed by the proposed petroleum activities in the Lofoten area is currently a subject of intense political as well as scientific debate (Box I). This area is important for the earliest life stages of several fish species spawning along the west and north coasts...

Awarded: NOK 8.7 mill.

Project Period: 2010-2014

Location: Oslo

HAVBRUK2-Stort program for havbruksforskning

Translating the cod genome for aquaculture

In this period (6 months) we have essentially worked on the completion of papers base don results from the three WPs WP 1: We have written a paper on the new cod genome assembly (cod 2). The new version of the genome assembly is roughly 50-fold improved with respect to contingency. A new annot...

Awarded: NOK 6.0 mill.

Project Period: 2010-2016

Location: Oslo

FORINFRA-Nasj.sats. forskn.infrastrukt

Norwegian High-Throughput Sequencing Centre

This proposal to establish an internationally competitive Norwegian High-Throughput Sequencing Centre (NSC) is built upon the existing HTS instruments in Norway: the Illumina Genome Analyzer II (GAII), and the 454 (Roche) sequencing platforms at Institute of Medical Genetics (IMG) and Centre for...

Awarded: NOK 23.0 mill.

Project Period: 2010-2015

Location: Oslo

HAVBRUKS-Havbruk - en næring i vekst

The smolt probe - novel tools for assessment of smolt quality and marine performance in Atlantic salmon

Smolt quality is critical for successful salmon aquaculture, and poor smolt quality may generate a wide range of problems; increased mortality in seawater, increased vulnerability to diseases and poor growth, which in total represents a considerable loss. Therefore, the salmon industry continuou...

Awarded: NOK 2.5 mill.

Project Period: 2010-2012

Location: Vestland

HAVBRUKS-Havbruk - en næring i vekst

The salmon in a warmer world: Aerobic scope of Atlantic salmon at different temperatures

Norway can expect rising water temperatures, and the potential effect of this on the performance of farmed and wild Atlantic salmon (Salmo salar) is presently not understood. Long before a rise in water temperature reach the critical temperature (Tc) that is immediately leathal, it will affect t...

Awarded: NOK 3.3 mill.

Project Period: 2010-2013

Location: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Characterization of plant associated AlkB-like demethylases

AlkB-proteinet hos bakterier er et enzym som reparerer, dvs fjerner, skadelige metylgrupper i cellens arvestoff. Metylerende stoffer finnes både inne i celler og i miljøet, og AlkB motvirker derfor de negative effektene av slike stoffer. Multicellulære organismer, f. eks. planter og mennesker, ha...

Awarded: NOK 6.8 mill.

Project Period: 2009-2015

Location: Oslo

IS-NAD-Samarbeid med NORAD-land

Birkeland, Nils-Kåre. Norsk spesialist til India 2009

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Awarded: NOK 10,000

Project Period: 2009-2009

Location: Vestland

IS-STP-Statsstipendprogram, utlendinger

Simaiakis, Stylianos, Hellas, statsstipend 2008/09

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Awarded: NOK 70,000

Project Period: 2009-2009

Location: Vestland

IS-NAD-Samarbeid med NORAD-land

Cao, Yonghong, Kina. statsstipend 2008/09

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Awarded: NOK 0.13 mill.

Project Period: 2009-2009

Location: Vestland

HAVBRUKS-Havbruk - en næring i vekst

Effects of dietary composition, rearing regimes and seasonal growth patterns on muscle softness and gaping in Atlantic salmon.

The primary objective for the present knowledge-building project is to reveal the causal mechanisms behind the fillet gaping and muscle softness, observed in Atlantic salmon. We will run experimental feeding trials, where the outcomes of the previous obje ctive will be combined with the state-of-...

Awarded: NOK 2.0 mill.

Project Period: 2009-2013

Location: Vestland

HAVBRUKS-Havbruk - en næring i vekst

New feeding strategies for Atlantic halibut and cod larvae to increase the output of high quality juveniles in production systems

The aim of the project is to establish new feeding strategies for halibut and cod larvae in the live-prey stage to improve growth, survival and quality in production systems. The project is based on break-through results in a pilot study where we demonstr ated that by controlling diurnal light an...

Awarded: NOK 3.8 mill.

Project Period: 2009-2012

Location: Vestland

HAVBRUKS-Havbruk - en næring i vekst

Fish welfare assessment through brain function: Impacts of environmental stress on brain plasticity and behaviour

Developing reliable measures of fish welfare is a priority within Norway and the EU. Although fish welfare definitions vary, a key aim is to provide environments that minimize stressors that impact health and the animal?s mental function. In mammals, prol onged stress can affect brain function to...

Awarded: NOK 3.1 mill.

Project Period: 2009-2012

Location: Vestland

FRIMEDBIO-Fri prosj.st. med.,helse,biol

The muscle excitation-transcription coupling

The composition of muscle is related to the risk of developing life style diseases such as obesity and type II diabetes. Muscle is a permanent tissue, but the phenotype can nevertheless be changed by changing the pattern of activity such as by exercise. C hanges in the pattern of action potential...

Awarded: NOK 6.2 mill.

Project Period: 2009-2014

Location: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Molecular mechanisms of androgen action

Androgens are essential for a wide range of important biological processes. These include the development and maintenance of male reproductive organs, hair cycle and skeletal muscle, as well as regulation of lipid metabolism and bone remodelling. Androgen s are implicated in pathological processe...

Awarded: NOK 6.2 mill.

Project Period: 2009-2013

Location: Oslo

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Maturation of the electrophysiological and intracellular signaling systems in teleost gonadotropes during puberty

Hovedmålet til dette prosjektet er å belyse hvordan reguleringsmekanismen til de hormonproduserende gonadotrope cellene i hypofysen modnes under pubertetsutviklingen, med fokus på komponenter som deltar i elektrofysiologisk signalisering trigget av frigjø ringshormonet GnRH. Vi bruker torsk og me...

Awarded: NOK 6.6 mill.

Project Period: 2009-2014

Location: Oslo