0 projects

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Antibody glycosylation and bone loss in cancer

Myelomatose er en kreftform som skyldes opphopning av maligne plasmaceller i beinmargen. Plasmaceller er antistoffproduserende celler, og et av de viktigste diagnostiske kriteriene for myelomatose er funn av monoklonale antistoffer, såkalt M-komponent, i blodet til pasientene. Et annet særtrekk v...

Awarded: NOK 9.9 mill.

Project Period: 2018-2023

Location: Trøndelag - Trööndelage

STAMCELLER-Stamcelleforskning

Influence of inflammation and cancer on mesenchymal stem cell function

Impaired mesenchymal stem cell function and dysregulated osteoblastogenesis is a common feature of diseases such as multiple myeloma, breast cancer metastasizing to bone and some autoimmune diseases. The consequences for the affected patients are pain, fr equent fractures and severely reduced qua...

Awarded: NOK 3.4 mill.

Project Period: 2009-2013

Location: Trøndelag - Trööndelage