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FRIMED2-FRIPRO forskerprosjekt, medisin og helse

The GABA-betaine transporter (BGT1): protection against alcoholic liver disease

Alkoholmisbruk og høy fettinntak medfører et antall helseproblemer inkludert leversykdom (alkoholindusert leversykdom, ALD; non-alkoholisk leversykdom, NALD). Metioninmetabolismen er forstyrret i ALD/NALD, og både alkohol og mye fett øker behovet for betain. Leveren kan skaffe seg betain enten ve...

Awarded: NOK 9.0 mill.

Project Period: 2015-2022

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Understanding the System of Neurotransporters

The proposed project is a system-biology approach to transport across brain plasma membranes focusing on neurotransmitter inactivation and water transport. The primary aim is to prepare the ground for a large scale approach to understand what all the hund reds of transporter and ion channels do t...

Awarded: NOK 5.3 mill.

Project Period: 2007-2011

Location: Oslo

FRIBIO-Biologi og biomedisin

Dynamic 3-D modelling of the synaptic environment: The roles of transporters in controlling receptor activation and water transport

Prevention and cure of neurological diseases are hampered by a lack of knowledge of the underlying pathogenetic mechanisms which involve a complex system of transporter proteins. The primary objective of this proposal is to uncover how transporters limit activation of brain neurotransmitter recep...

Awarded: NOK 2.2 mill.

Project Period: 2006-2009

Location: Oslo

YFF-Yngre, fremragende forskere

Toppforskning - Inaktivering av glutamat

...

Awarded: NOK 4.5 mill.

Project Period: 2004-2007

Location: Oslo

BIOFYS-Fysiologiske og anatomiske fag

Sabbatical/Forskningstermin: Crystallization of a glutamate transporter

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Awarded: NOK 0.14 mill.

Project Period: 2004-2005

Location: Oslo

FUGE-Funksjonell genomforskn.i Norg

Transgenic models in neuroscience: Uncovering the secrets of the hippocampal formation

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Awarded: NOK 8.0 mill.

Project Period: 2004-2009

Location: Oslo

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