0 projects

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FRIBIO-Biologi og biomedisin

Glutamate and lactate: Jason-faced actors in neurology

Excitatory amino acids play dual roles in the brain: they are physiological transmitters but have the potential to damage brain tissue. The same may be true for lactate, an important intermediate in cell metabolism. The project will study the roles of exc itatory amino acids and lactate transport...

Awarded: NOK 3.0 mill.

Project Period: 2006-2009

Location: Oslo

FRIBIO-Biologi og biomedisin

Dynamic 3-D modelling of the synaptic environment: The roles of transporters in controlling receptor activation and water transport

Prevention and cure of neurological diseases are hampered by a lack of knowledge of the underlying pathogenetic mechanisms which involve a complex system of transporter proteins. The primary objective of this proposal is to uncover how transporters limit activation of brain neurotransmitter recep...

Awarded: NOK 2.2 mill.

Project Period: 2006-2009

Location: Oslo

FRIBIO-Biologi og biomedisin

PPAR activation and mitochondrial function in obesity related diseases.

Disorders of lipid metabolism are intimately connected to many common, life-style related diseases. Obesity and obesity-related disorders, often referred to as the metabolic syndrome, is a serious condition with the presence of a number of risk factors li ke overweight, dyslipidaemia, hypertensio...

Awarded: NOK 3.1 mill.

Project Period: 2006-2010

Location: Vestland

PSYKISK-Psykisk helse

Coping and protection - A longitudinal study of children and their mothers

The principal objective is to attain knowledge about pathways to good social competence or mental health problems among children and their mothers. The longitudinal perspective implies studying health outcomes among children associated with age typical de velopment, and maternal health outcomes a...

Awarded: NOK 2.1 mill.

Project Period: 2006-2011

Location: Oslo

FRIMED-Klinisk medisin og folkehelse

Injury in newborn infants. Basic mechanisms related to oxidative stress and bilirubin encephalopathy

In this project we plan to continue our long term studies regarding basic mechanisms of brain injury in newborn infants. We have previously shown that oxidative stress both in preterm and term infants induces long term potential harmful effects that may affect growth and development. As the f...

Awarded: NOK 3.0 mill.

Project Period: 2006-2010

Location: Oslo

SIP-Strategiske instituttprogram

State Failure and Regional Insecurity: A NUPI and PRIO Strategic Collaboration Program

The project will bring together researchers from PRIO and NUPI to explore the linkages between state failure and regional security issues. The program will be founded on four case studies, focusing on Afghanistan, the Democratic Republic of Congo, Georgia and the Horn of Africa. They will focus ...

Awarded: NOK 4.2 mill.

Project Period: 2006-2010

Location: Oslo

FRIBIO-Biologi og biomedisin

Allopolyploid evolution in plants: patterns and processes within the genus Viola

This project aims at disentangling ?diploid? lineages in ancient polyploid groups using the genus Viola (Violaceae) as study object. Chromosome numbers, isozymes and our preliminary data on two low-copy nuclear RNA polymerase genes all suggest that the ma jority of temperate groups of Viola have ...

Awarded: NOK 2.7 mill.

Project Period: 2006-2009

Location: Oslo

FRIBIO-Biologi og biomedisin

Genetic basis and evolution of ventral plumage melanism in skuas (Stercorariidae)

The genetic basis of phenotypic change and adaptation is one of the major outstanding problems in evolutionary biology. Until recently it has been difficult to identify the genes involved, particularly in wild populations. The biochemical pathways of mela nin-based fur and plumage pigmentation ar...

Awarded: NOK 2.7 mill.

Project Period: 2006-2010

Location: Troms - Romsa - Tromssa

FRIBIO-Biologi og biomedisin

Did vascular plants and bryophytes survive the last ice age in Scandinavia?

Glacial survival versus postglacial immigration of the Scandinavian alpine flora has been debated for more than 100 years, and has recently received increased attention with the development of molecular tools. Many vascular plant species occur disjunctly on both sides of the North Atlantic Ocean,...

Awarded: NOK 5.0 mill.

Project Period: 2006-2010

Location: Oslo

FRIBIO-Biologi og biomedisin

Signal evolution: adaptation and constraint

A central challenge in evolutionary biology is to understand what determines the reliability and flexibility of animal signals. We investigate signal evolution and signal discrimination in two contexts, mate choice and mimicry, with focus on how adaptatio n is affected by learning, plasticity, va...

Awarded: NOK 4.8 mill.

Project Period: 2006-2009

Location: Oslo

BEDSAM-Bedriftens samfunnsansvar

International developments, dissemination and implementation of CSR in the Norwegian clothing sector

By a trial research design this project aims to follow the Norwegian branch organisations engagement in the national and international development of Corporate Social Responsibility (CSR) and to study how these processes disseminates and influences the cl othing branch in Norway at the chain and ...

Awarded: NOK 3.1 mill.

Project Period: 2006-2010

Location: Rogaland

FRIBIO-Biologi og biomedisin

Coeliac disease (CD) and rheumatoid arthritis (RA); mapping the shared features in order to understand autoimmunity

There has been a huge advance in the understanding of coeliac disease (CD) in recent years. Our group has made several important contributions to this improved understanding. Research done by other groups has started to unravel aspects of the pathogenesis of rheumatoid arthritis (RA) that at sev...

Awarded: NOK 2.9 mill.

Project Period: 2006-2009

Location: Oslo

GLOBHELS-Global helse

Strengthening human resources for health. A study of health worker availability and performance in Tanzania

Shortage of health personnel and poor health worker performance are among the most pressing problems of health systems in low-income countries. This proposal represents a strategic initiative to provide evidence that will be valuable in addressing these f undamental problems. The initiative is a ...

Awarded: NOK 9.6 mill.

Project Period: 2006-2012

Location: Vestland

FRIMEDBIO-Fri prosj.st. med.,helse,biol

Cell cycle regulation: the role of replication clamps and interacting proteins

DNA replication is executed by enzymes called polymerases. The polymerases are tethered to the DNA template by binding to so-called clamps, which are doughtnut-shaped protein complexes encircling the DNA. The clamps are being loaded onto the DNA by clamp loaders, another protein complex. All orga...

Awarded: NOK 2.3 mill.

Project Period: 2006-2013

Location: Oslo

FRINAT-Matematikk og naturvitenskap

Life in the volcanic crust of the early Earth: conditions, timing and depth

Over the past decade, our group has provided convincing evidence that alteration of basaltic glass in pillow lavas of modern and ancient oceanic crust is partially controlled by microbial activity. As a result, bioactivity may have important implications for global chemical fluxes and the evoluti...

Awarded: NOK 5.5 mill.

Project Period: 2006-2010

Location: Vestland

VERDIKT-Kjernekomp.og verdiskaping IKT

Cross-Layer Optimization of Short-Range Wireless Sensor Networks

In this summary mainly the planned research of the Norwegian side is targeted. One important task will be the co-optimization of link adaptation schemes and node circuitry power consumption, for low-complexity energy-efficient transmission in short-rang e WSNs. The Finnish team will take the ma...

Awarded: NOK 5.7 mill.

Project Period: 2006-2009

Location: Trøndelag - Trööndelage

HAVBRUKS-Havbruk - en næring i vekst

Jern og toksiske blandsoner i norske settefiskanlegg - bruk av silikat-lut som tiltaksmiddel

Ulike kilder kan bidra til forhøyet nivå av Fe i driftsvann ved settefiskanlegg: jernholdig grunnvann eller humøst overflatevann som råvann, samt fôr-rester og blod/feaces fra fisk. Fe kan foreligge i ulike fysisk-kjemiske tilstandsformer, fra enkle ioner til komplekser, kolloider og partikler. ...

Awarded: NOK 5.7 mill.

Project Period: 2006-2009

Location: Akershus

FRIBIO-Biologi og biomedisin

The Biosynthesis of NAD in Humans: Isozymes and Subcellular Compartmentation

NAD is essential for energy transduction. It is also a key molecule in a variety of central signaling pathways. Nevertheless, surprisingly little is not known about its biosynthesis. Our recent research has established that NAD biosynthesis is absent from the cytosol: the three human isoforms of...

Awarded: NOK 3.1 mill.

Project Period: 2006-2009

Location: Vestland

SIP-Strategiske instituttprogram

Tillit som betingelse for samarbeid og utvikling i Nord

Prosjektet skal utvikle kompetanse om Nordområdeproblematikk gjennom teoretisk refleksjon og empiriske undersøkelser av sosiale/menneskelige vilkår for tillitsbygging, samarbeid og utvikling i Nordområdene. Gjennom å bruke tillit som inntak til å fokuse re på sosial organisering og sosiale rela...

Awarded: NOK 3.0 mill.

Project Period: 2006-2009

Location: Troms - Romsa - Tromssa

FRIBIO-Biologi og biomedisin

Inferring regional patterns from local dynamics using spatially explicit simulation modelling and remote sensing data

The availability and quality of field data is one of the most severe limitations to studies of spatio-temporal population processes such as cyclic dynamics and population synchrony. We propose here an approach that will overcome many limitations concernin g data adequacy and which can dramaticall...

Awarded: NOK 3.3 mill.

Project Period: 2006-2009

Location: Troms - Romsa - Tromssa

FRINAT-Matematikk og naturvitenskap

Rare-Earth Metal-Based Ziegler-Natta Catalysts. Structure-Reactivity Relations in Homogeneous and Heterogenized Catalysts

The long-term goal of the project is to systematically study the reaction pathways and activation sequences in empirically designed multicomponent Ziegler-Natta catalysts and, based on fundamental insights, to develop more efficient polymerization catalys ts. The focus of the predominantly synth...

Awarded: NOK 3.8 mill.

Project Period: 2006-2009

Location: Vestland

FRINAT-Matematikk og naturvitenskap

Synthesis of Agelasines, Asmarines and Analogs, and Evaluation of Their Bioactivities

Project summary Agelasines are 7,9-dialkylpurinium salts isolated from marine sponges (Agelas sp.) and asmarines are neutral purine derivatives isolated from Raspaila sp. sponges. These two classes of purine natural products are structurally related; they both contain terpenoid side chains. Up t...

Awarded: NOK 4.3 mill.

Project Period: 2006-2010

Location: Oslo

HAVBRUKS-Havbruk - en næring i vekst

Skeletal malformations in farmed salmon and cod: a functional approach to determine causalities and mechanisms

Skeletal deformities cause severe losses both in salmon and cod production. This research platform aims to gain further insight into the normal growth and development of the vertebral column of salmon, and how current culture techniques may disrupt norma l growth inducing bone related pathologic...

Awarded: NOK 16.0 mill.

Project Period: 2006-2010

Location: Troms - Romsa - Tromssa

SIP-Strategiske instituttprogram

Strategic Program on Global Health and Development

The strategic program at CMI is linked up to a larger research program on global health and development in Bergen. Within the SIP, one sub-project is directly linked to the larger project that focuses on mobilization of human resources within the health s ector in developing countries. The SIP al...

Awarded: NOK 2.1 mill.

Project Period: 2006-2010

Location: Vestland

HAVBRUKS-Havbruk - en næring i vekst

Optimizing the nutritional value of non-marine protein sources in extruded fish feed.

Considerable increases in the food fish demand, a shortage of fishmeal and fish oil and the occurrence of contaminants in marine feed ingredients have forced the aquaculture industry and the research community to explore other ingredients for farmed fish. Increased use of protein-rich ingredient...

Awarded: NOK 4.0 mill.

Project Period: 2006-2010

Location: Akershus

HAVBRUKS-Havbruk - en næring i vekst

Wave and current loads on net panels and net cages

SINTEF Fisheries and Aquaculture (SFH) has over the last five years developed a numerical model (3dNet) of a three dimensional net structure exposed to waves and current. This activity has been financed by the Research Council of Norway through two projec ts: 3 Dimensional netpen movement and moo...

Awarded: NOK 4.9 mill.

Project Period: 2006-2009

Location: Trøndelag - Trööndelage

HAVBRUKS-Havbruk - en næring i vekst

Production of all-female cod as a means to circumvent problems with early puberty in males: Studies on sex determination and differentiation

Early puberty is a major problem in cod farming both due to negative impact on production performance in on-growth farms, and due to risk of negative genetic impact on wild stocks following spawning in sea cages or after escape. Use of all-female stocks c an mitigate some of these problems. Howev...

Awarded: NOK 3.9 mill.

Project Period: 2006-2010

Location: Vestland

HAVBRUKS-Havbruk - en næring i vekst

Salmon louse vaccine - identification and evaluation of novel antigens

The salmon louse is one of the main problems for the salmon farming industry both in Norway and in other countries. Pesticides and different management measures currently control the salmon louse. However, only a few types of drugs are available for salmo n louse combat and there are several repo...

Awarded: NOK 9.6 mill.

Project Period: 2006-2010

Location: Vestland

SIP-Strategiske instituttprogram

Development and use of ensemble based data assimilation methods in atmospheric chemistry modelling

As an internationally recognized centre for research and expertise in air pollution and atmospheric chemistry, NILU provides technical premises for a sustainable management of the atmosphere. This ranges from assessment of air quality in urban environment s, to global chemistry in the stratospher...

Awarded: NOK 4.5 mill.

Project Period: 2006-2010

Location: Akershus

HAVBRUKS-Havbruk - en næring i vekst

Motivational states and coping ability as operational welfare indicators in farmed fish

To improve welfare of farmed fish there is a need to develop objective indicators that can be used to assess, manage and document welfare. The high number of individuals in aquaculture production units puts constraints on which indicators that are likely to be operational in the industry. Behavio...

Awarded: NOK 6.0 mill.

Project Period: 2006-2009

Location: Vestland

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